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Molecular Biology

D-Index
90
Citations
31031
World Ranking
732
National Ranking
395

Overview

Lester F. Lau is affiliated with the University of Illinois at Chicago in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Molecular Biology, Hepatology, Immunology, Surgery, and Radiology, Nuclear Medicine, and Imaging.

The scientist's work centers on several main topics including Connective Tissue Growth Factor Research, Liver physiology and pathology, Renal and related cancers, Tissue Engineering and Regenerative Medicine, Diet, Metabolism, and Disease, Liver Disease Diagnosis and Treatment, and Cancer, Lipids, and Metabolism.

Lester F. Lau has contributed to a range of recent papers, some of which include:

  • Fructose stimulated de novo lipogenesis is promoted by inflammation, 2020, Nature Metabolism
  • Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2, 2022, JCI Insight
  • CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling, 2020, Nature Communications
  • Cellular communication network factor 1-stimulated liver macrophage efferocytosis drives hepatic stellate cell activation and liver fibrosis, 2022, Hepatology Communications
  • Neuronally differentiated macula densa cells regulate tissue remodeling and regeneration in the kidney, 2024, Journal of Clinical Investigation

Lester F. Lau frequently collaborates with other researchers. Notable co-authors include:

  • Naiyuan Cheng
  • KH Kim
  • Georgina Gyarmati
  • Urvi Nikhil Shroff
  • Anne Riquier-Brison

The primary venues where Lester's work is published include:

  • Methods in molecular biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Metabolism
  • JCI Insight
  • Nature Communications

Best Publications

  • MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

    Hong Sun;Catherine H. Charles;Lester F. Lau;Nicholas K. Tonks

  • Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc

    Lester F. Lau;Daniel Nathans

  • The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

    Joon Il Jun;Lester F. Lau

  • A gene activated by growth factors is related to the oncogene v-jun

    Kevin Ryder;Lester F. Lau;Daniel Nathans

  • Rapid and preferential activation of the c-jun gene during the mammalian UV response.

    Yoram Devary;Roberta A. Gottlieb;Lester F. Lau;Michael Karin

  • A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences

    Barbara A. Christy;Lester F. Lau;Daniel Nathans

  • The CCN family of angiogenic regulators: the integrin connection.

    Lester F Lau;Stephen C.-T Lam

  • Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

    Lester F. Lau;D. Nathans

  • Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo.

    Alexander M. Babic;Chih-Chiun Chen;Lester F. Lau

  • Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

    Joon Il Jun;Lester F. Lau

  • Functions and mechanisms of action of CCN matricellular proteins.

    Chih Chiun Chen;Lester F. Lau

  • CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth.

    Alexander M. Babic;Maria L. Kireeva;Tatiana V. Kolesnikova;Lester F. Lau

  • A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily.

    Thomas G. Hazel;Daniel Nathans;Lester F. Lau

  • Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction.

    D P Bartel;M Sheng;L F Lau;M E Greenberg

  • CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity

    Fan E. Mo;Andrew G. Muntean;Chih Chiun Chen;Donna B. Stolz

  • Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition.

    Dimitri G. Pestov;Žaklina Strezoska;Lester F. Lau

  • An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

    Barbara A. Christy;Laura K. Sanders;Lester F. Lau;Neal G. Copeland

  • The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts.

    Chih-Chiun Chen;Ningyu Chen;Lester F. Lau

  • Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion.

    Maria L. Kireeva;Fan E. Mo;George P. Yang;Lester F. Lau

  • Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: Coordinate regulation with c-fos or c-myc (growth factors/gene expression/mRNA stability/protooncogenes)

    Lester F. Lau;Daniel Nathans

Frequent Co-Authors

Pradip Raychaudhuri
Pradip Raychaudhuri University of Illinois at Chicago
Robert H. Costa
Robert H. Costa University of Illinois at Chicago
Daniel Nathans
Daniel Nathans Johns Hopkins University
Angela L. Tyner
Angela L. Tyner University of Illinois at Chicago
Bernard Perbal
Bernard Perbal Université Paris Cité
Jeffrey W. Roberts
Jeffrey W. Roberts Cornell University
Ray Wu
Ray Wu Cornell University
Maria B. Grant
Maria B. Grant University of Alabama at Birmingham
Herman Yeger
Herman Yeger University of Toronto
Andrew Leask
Andrew Leask University of Saskatchewan

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