What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Phosphorylation
Cell biology, Signal transduction, Biochemistry, Protein kinase B and Protein kinase C are his primary areas of study.
Alex Toker specializes in Cell biology, namely Kinase.
His studies deal with areas such as Cancer and Cancer research as well as Signal transduction.
His work in Protein kinase B is not limited to one particular discipline; it also encompasses PI3K/AKT/mTOR pathway.
The various areas that Alex Toker examines in his PI3K/AKT/mTOR pathway study include Molecular biology and Motility.
His study focuses on the intersection of Protein kinase C and fields such as MAP2K7 with connections in the field of ASK1, MAP kinase kinase kinase, Casein kinase 2, Actin cytoskeleton and Protein-Serine-Threonine Kinases.
His most cited work include:
- Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate (1335 citations)
- Signalling through the lipid products of phosphoinositide-3-OH kinase (1196 citations)
- AKT/PKB Signaling: Navigating the Network (1191 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Cell biology, Cancer research, Protein kinase B, PI3K/AKT/mTOR pathway and Signal transduction.
His Biochemistry research extends to the thematically linked field of Cell biology.
His biological study spans a wide range of topics, including Cancer cell, Cancer, Breast cancer, Triple-negative breast cancer and Chemotherapy.
His Protein kinase B research incorporates elements of Carcinogenesis, Ubiquitin ligase and PTEN.
He has researched PI3K/AKT/mTOR pathway in several fields, including Cell growth and Kinase activity.
His Signal transduction course of study focuses on Transcription factor and Tumor progression.
He most often published in these fields:
- Cell biology (51.16%)
- Cancer research (43.60%)
- Protein kinase B (35.47%)
What were the highlights of his more recent work (between 2016-2020)?
- Cancer research (43.60%)
- PI3K/AKT/mTOR pathway (33.72%)
- Protein kinase B (35.47%)
In recent papers he was focusing on the following fields of study:
Alex Toker mostly deals with Cancer research, PI3K/AKT/mTOR pathway, Protein kinase B, Triple-negative breast cancer and Cancer.
His Cancer research research is multidisciplinary, relying on both Cancer cell, Breast cancer and Cancer gene.
PI3K/AKT/mTOR pathway is a subfield of Cell biology that Alex Toker tackles.
His Cell biology research focuses on Hypoxia and how it connects with Cell culture and Glutathione.
Protein kinase B is a primary field of his research addressed under Signal transduction.
His research in Kinase focuses on subjects like Phosphorylation, which are connected to Nuclear protein and Sterol regulatory element-binding protein.
Between 2016 and 2020, his most popular works were:
- AKT/PKB Signaling: Navigating the Network (1191 citations)
- PI3K signaling in cancer: beyond AKT. (163 citations)
- Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer. (79 citations)
In his most recent research, the most cited papers focused on:
Alex Toker spends much of his time researching PI3K/AKT/mTOR pathway, Cancer research, Cancer, Breast cancer and Triple-negative breast cancer.
His study on PI3K/AKT/mTOR pathway is covered under Cell biology.
The AKT1 research Alex Toker does as part of his general Cell biology study is frequently linked to other disciplines of science, such as Demethylase, therefore creating a link between diverse domains of science.
His Cancer research research integrates issues from Fusion gene and Point mutation.
His Cancer study combines topics in areas such as Aspirin, AMPK, Combination therapy and Endocrinology.
His work investigates the relationship between Breast cancer and topics such as mTORC1 that intersect with problems in Cell, Insulin resistance, Neuroscience, Kinase and Disease.
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