D-Index & Metrics Best Publications
John A. Badwey

John A. Badwey

Brigham and Women's Hospital
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Phosphorylation

John A. Badwey spends much of his time researching Biochemistry, Superoxide, Protein kinase A, Protein kinase C and Cell biology. His study in the field of Superoxide release is also linked to topics like Text mining. His Superoxide research is multidisciplinary, incorporating perspectives in Polyunsaturated fatty acid, Arachidonic acid, Lipid signaling and Hydrogen peroxide.

In the field of Protein kinase A, his study on Akt/PKB signaling pathway overlaps with subjects such as Vascular smooth muscle contraction. His MAP2K7 research extends to the thematically linked field of Protein kinase C. When carried out as part of a general Cell biology research project, his work on NADPH oxidase complex, Phosphorylation, NADPH oxidase and Wortmannin is frequently linked to work in MAPK1, therefore connecting diverse disciplines of study.

His most cited work include:

  • Active Oxygen Species and the Functions of Phagocytic Leukocytes (980 citations)
  • Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. (205 citations)
  • cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils. (183 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Biochemistry, Superoxide, Cell biology, Kinase and Phosphorylation. His study in Protein kinase C, Protein kinase A, Mitogen-activated protein kinase kinase, MAP2K7 and c-Raf is carried out as part of his studies in Biochemistry. His work deals with themes such as Phagocytosis, Oxidase test, Phorbol and Stimulation, which intersect with Superoxide.

His biological study spans a wide range of topics, including Receptor and Cofilin. John A. Badwey combines subjects such as Molecular biology and Chemotaxis with his study of Kinase. His studies in Phosphorylation integrate themes in fields like Proinflammatory cytokine and Peptide.

He most often published in these fields:

  • Biochemistry (75.90%)
  • Superoxide (45.78%)
  • Cell biology (51.81%)

What were the highlights of his more recent work (between 2000-2013)?

  • Cell biology (51.81%)
  • Phosphorylation (39.76%)
  • Kinase (48.19%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, Phosphorylation, Kinase, Biochemistry and Molecular biology. His Cell biology research includes themes of Calmodulin and Cofilin, Actin cytoskeleton. His study in Phosphorylation is interdisciplinary in nature, drawing from both Receptor and Chemotaxis.

His biological study deals with issues like Signal transduction, which deal with fields such as Proinflammatory cytokine. Many of his studies on Biochemistry apply to Stereochemistry as well. His study looks at the relationship between Molecular biology and fields such as Diacylglycerol kinase, as well as how they intersect with chemical problems.

Between 2000 and 2013, his most popular works were:

  • Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis (118 citations)
  • A Molecular Defect in Intracellular Lipid Signaling in Human Neutrophils in Localized Aggressive Periodontal Tissue Damage (92 citations)
  • A Stable Aspirin-Triggered Lipoxin A4 Analog Blocks Phosphorylation of Leukocyte-Specific Protein 1 in Human Neutrophils (58 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Phosphorylation
  • Biochemistry

His primary areas of study are Molecular biology, Phosphorylation, Cell biology, Chemotaxis and Inflammation. John A. Badwey focuses mostly in the field of Molecular biology, narrowing it down to matters related to Kinase and, in some cases, Intracellular. Superoxide is closely connected to Signal transduction in his research, which is encompassed under the umbrella topic of Chemotaxis.

His study with Superoxide involves better knowledge in Biochemistry. His work in Inflammation tackles topics such as Periodontitis which are related to areas like Protein kinase C. His Phosphatase research incorporates themes from Staurosporine, Calmodulin, Cofilin and Phospholipase C.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Active Oxygen Species and the Functions of Phagocytic Leukocytes

John A. Badwey;Manfred L. Karnovsky.
Annual Review of Biochemistry (1980)

1590 Citations

Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin.

J A Badwey;J T Curnutte;J M Robinson;C B Berde.
Journal of Biological Chemistry (1984)

311 Citations

cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.

J A Badwey;J T Curnutte;M L Karnovsky.
Journal of Biological Chemistry (1981)

292 Citations

Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis

M. Karima;A. Kantarci;T. Ohira;H. Hasturk.
Journal of Leukocyte Biology (2005)

193 Citations

Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate.

J T Curnutte;J A Badwey;J M Robinson;M J Karnovsky.
Journal of Biological Chemistry (1984)

191 Citations

Superoxide release by neutrophils: Synergistic effects of a phorbol ester and a calcium ionophore

John M. Robinson;John A. Badwey;Manfred L. Karnovsky;Morris J. Karnovsky.
Biochemical and Biophysical Research Communications (1984)

177 Citations

Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils

Jiabing Ding;C. J. Vlahos;Ruichun Liu;R. F. Brown.
Journal of Biological Chemistry (1995)

174 Citations

The NADPH oxidase complex of phagocytic leukocytes: a biochemical and cytochemical view.

John M. Robinson;John A. Badwey.
Histochemistry and Cell Biology (1995)

143 Citations

A Molecular Defect in Intracellular Lipid Signaling in Human Neutrophils in Localized Aggressive Periodontal Tissue Damage

Karsten Gronert;Alpdogan Kantarci;Bruce D. Levy;Clary B. Clish.
Journal of Immunology (2004)

142 Citations

Protein phosphorylation associated with the stimulation of neutrophils. Modulation of superoxide production by protein kinase C and calcium

Paul G. Heyworth;John A. Badwey;John A. Badwey.
Journal of Bioenergetics and Biomembranes (1990)

141 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing John A. Badwey

Charles N. Serhan

Charles N. Serhan

Brigham and Women's Hospital

Publications: 27

Bernard M. Babior

Bernard M. Babior

Scripps Research Institute

Publications: 26

Thomas E. Van Dyke

Thomas E. Van Dyke

Harvard University

Publications: 26

Kathleen G. Morgan

Kathleen G. Morgan

Boston University

Publications: 25

John T. Curnutte

John T. Curnutte

Scripps Research Institute

Publications: 23

Alfred I. Tauber

Alfred I. Tauber

Boston University

Publications: 22

Gary M. Bokoch

Gary M. Bokoch

Scripps Research Institute

Publications: 22

Antonio Ferrante

Antonio Ferrante

University of Adelaide

Publications: 22

Mark T. Quinn

Mark T. Quinn

Montana State University

Publications: 20

Mary C. Dinauer

Mary C. Dinauer

Washington University in St. Louis

Publications: 19

Anthony W. Segal

Anthony W. Segal

University College London

Publications: 18

William M. Nauseef

William M. Nauseef

University of Iowa

Publications: 17

Sergio Grinstein

Sergio Grinstein

University of Toronto

Publications: 16

Manfred L. Karnovsky

Manfred L. Karnovsky

Harvard University

Publications: 15

Algirdas J. Jesaitis

Algirdas J. Jesaitis

Montana State University

Publications: 15

Bruce D. Levy

Bruce D. Levy

Brigham and Women's Hospital

Publications: 14

Trending Scientists

Xiang Cheng

Xiang Cheng

Peking University

Garrett Birkhoff

Garrett Birkhoff

Harvard University

Bryan W. Karney

Bryan W. Karney

University of Toronto

Shu Seki

Shu Seki

Kyoto University

Marc Ouellette

Marc Ouellette

Université Laval

Roger A. Leigh

Roger A. Leigh

University of Cambridge

Alan R. Longhurst

Alan R. Longhurst

Bedford Institute of Oceanography

Meritxell Gros

Meritxell Gros

Catalan Institute for Water Research

Janine I. Rossato

Janine I. Rossato

Federal University of Rio Grande do Norte

Lorna W. Role

Lorna W. Role

Stony Brook University

Jane L. Mathias

Jane L. Mathias

University of Adelaide

Peter Zwanzger

Peter Zwanzger

Ludwig-Maximilians-Universität München

Martine Hébert

Martine Hébert

University of Quebec at Montreal

Robert N. Foley

Robert N. Foley

University of Minnesota

Richard N. Jones

Richard N. Jones

Brown University

Linda Weiss

Linda Weiss

University of Sydney

Something went wrong. Please try again later.