D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 110 Citations 36,433 462 World Ranking 2449 National Ranking 1419

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Enzyme
  • Gene

His primary areas of study are Internal medicine, Endocrinology, Immunology, Alcoholic liver disease and Liver injury. His research on Internal medicine frequently connects to adjacent areas such as Gastroenterology. His Endocrinology research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine and Zinc deficiency.

Craig J. McClain focuses mostly in the field of Alcoholic liver disease, narrowing it down to matters related to Liver function and, in some cases, Liver regeneration. His Liver injury study combines topics in areas such as Necrosis, Oxidative stress, Intestinal permeability and Pathogenesis. In his work, Antioxidant, Glutathione, IC50, Phosphorylation and IκB kinase is strongly intertwined with Pharmacology, which is a subfield of Tumor necrosis factor alpha.

His most cited work include:

  • Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients (481 citations)
  • Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin. (384 citations)
  • Cytokines in alcoholic liver disease. (345 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Internal medicine, Endocrinology, Liver injury, Alcoholic liver disease and Gastroenterology. Steatosis, Fatty liver, Alcoholic hepatitis, Tumor necrosis factor alpha and Cytokine are the core of his Internal medicine study. His Endocrinology research is multidisciplinary, incorporating elements of Inflammation, Nonalcoholic fatty liver disease and Fructose.

His Liver injury study combines topics from a wide range of disciplines, such as Alcohol, Biochemistry and Hepatocyte. His work deals with themes such as Liver disease and Pathology, which intersect with Alcoholic liver disease. His Liver disease research is multidisciplinary, relying on both Chronic liver disease and Cirrhosis.

He most often published in these fields:

  • Internal medicine (62.15%)
  • Endocrinology (40.25%)
  • Liver injury (29.10%)

What were the highlights of his more recent work (between 2017-2021)?

  • Internal medicine (62.15%)
  • Alcoholic liver disease (26.27%)
  • Endocrinology (40.25%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Internal medicine, Alcoholic liver disease, Endocrinology, Liver injury and Pharmacology. His Internal medicine study combines topics from a wide range of disciplines, such as Gastroenterology and Alcohol. Craig J. McClain studied Alcoholic liver disease and Fatty liver that intersect with Fibrosis.

His Endocrinology research is multidisciplinary, incorporating elements of Fructose, Gut flora, Downregulation and upregulation, Hepatocyte and Programmed cell death. His Liver injury study deals with Ethanol intersecting with Fatty acid. His work deals with themes such as Rolipram, Metabolome, Proinflammatory cytokine and Liver fibrosis, which intersect with Pharmacology.

Between 2017 and 2021, his most popular works were:

  • Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota (137 citations)
  • Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota (137 citations)
  • Intestinal HIF-1α deletion exacerbates alcoholic liver disease by inducing intestinal dysbiosis and barrier dysfunction (44 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Gene

His main research concerns Alcoholic liver disease, Internal medicine, Liver injury, Endocrinology and Liver disease. Craig J. McClain has included themes like Steatosis, Steatohepatitis, Fatty liver and Gerontology in his Alcoholic liver disease study. His Steatosis research is multidisciplinary, relying on both Nonalcoholic fatty liver disease, Gene expression and Pharmacology.

His biological study spans a wide range of topics, including Gastroenterology, Apoptosis and Alcohol use disorder. His Liver injury research includes themes of Alcohol, Liquid diet, Alcohol abuse, Alcoholic hepatitis and Excretion. In the subject of general Endocrinology, his work in Ileum is often linked to Lactobacillus rhamnosus, thereby combining diverse domains of study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients

Alexander Khoruts;Laura Stahnke;Craig J. McClain;George Logan.
Hepatology (1991)

656 Citations

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin.

Ina Bergheim;Synia Weber;Miriam Vos;Sigrid Krämer.
Journal of Hepatology (2008)

581 Citations

Cytokines in alcoholic liver disease.

Craig J. McClain;Shirish Barve;Ion Deaciuc;Marcelo Kugelmas.
Seminars in Liver Disease (1999)

527 Citations

Green Tea Polyphenols Block Endotoxin-Induced Tumor Necrosis Factor-Production and Lethality in a Murine Model

Fajun Yang;Willem J. S. de Villiers;Craig J. McClain;Gary W. Varilek.
Journal of Nutrition (1998)

470 Citations

The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6.

Fajun Yang;Helieh S. Oz;Shirish Barve;Shirish Barve;Willem J. S. de Villiers.
Molecular Pharmacology (2001)

449 Citations

Abnormal zinc metabolism in type II diabetes mellitus

William B. Kinlaw;Allen S. Levine;John E. Morley;Stephen E. Silvis.
The American Journal of Medicine (1983)

447 Citations

Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study

Irina A. Kirpich;Natalia V. Solovieva;Svetlana N. Leikhter;Natalia A. Shidakova.
Alcohol (2008)

416 Citations

Cytokines and Alcoholic Liver Disease

Craig McClain;Daniell Hill;Jack Schmidt;Anna Mae Diehl.
Seminars in Liver Disease (1993)

388 Citations

Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes.

Swati Joshi-Barve;Shirish S. Barve;Kiranmayi Amancherla;Leila Gobejishvili.
Hepatology (2007)

385 Citations

Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment.

Lara Bull-Otterson;Wenke Feng;Irina Kirpich;Yuhua Wang.
PLOS ONE (2013)

366 Citations

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