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Immunology

D-Index
77
Citations
28373
World Ranking
1795
National Ranking
884

Overview

Huang-Ge Zhang is affiliated with the University of Louisville in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology, with notable activity across specialized subfields such as Molecular Biology, Immunology, Epidemiology, Infectious Diseases, and Developmental Neuroscience.

The scientist's work concentrates on several main topics including extracellular vesicles in disease, immune cells in cancer, gut microbiota and health, neurogenesis and neuroplasticity mechanisms, microRNA in disease regulation, immunotherapy and immune responses, as well as clinical research studies related to COVID-19.

Frequent co-authors collaborating with Huang-Ge Zhang include Jun Yan, Jingyao Mu, Kumaran Sundaram, Mukesh K. Sriwastva, and Michael L. Merchant.

The scientist's publications often appear in journals such as iScience, Nature Communications, Theranostics, SSRN Electronic Journal, and Small.

Recent papers authored or co-authored by Huang-Ge Zhang include:

  • Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming (2021, Cell Metabolism)
  • High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance (2021, Nature Communications)
  • Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis (2023, Nature Immunology)
  • Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis (2022, Theranostics)
  • A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients (2021, JCI Insight)

Best Publications

  • A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

    Dongmei Sun;Xiaoying Zhuang;Xiaoying Zhuang;Xiaoyu Xiang;Xiaoyu Xiang;Yuelong Liu

  • Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

    Xiaoying Zhuang;Xiaoyu Xiang;William Grizzle;Dongmei Sun

  • Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation.

    Yihua Cai;Xiaoyan Shen;Chuanlin Ding;Chunjian Qi

  • Grape exosome-like nanoparticles induce intestinal stem cells and protect mice from DSS-induced colitis.

    Songwen Ju;Jingyao Mu;Terje Dokland;Xiaoying Zhuang

  • Induction of myeloid-derived suppressor cells by tumor exosomes

    Xiaoyu Xiang;Anton Poliakov;Cunren Liu;Yuelong Liu

  • Correction: Corrigendum: Differential developmental requirement and peripheral regulation for dermal Vγ4 and Vγ6T17 cells in health and inflammation

    Yihua Cai;Feng Xue;Chris Fleming;Jie Yang

  • Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity

    Kimihisa Ichikawa;Weimin Liu;Limin Zhao;Zheng Wang

  • Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles

    Jingyao Mu;Xiaoying Zhuang;Qilong Wang;Hong Jiang

  • Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

    Rajbir Singh;Sandeep Chandrashekharappa;Sobha R. Bodduluri;Becca V. Baby

  • Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function

    Cunren Liu;Shaohua Yu;Kurt Zinn;Jianhua Wang

  • Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit

    Baomei Wang;Xiaoying Zhuang;Zhong Bin Deng;Hong Jiang

  • Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming.

    Samantha M. Morrissey;Fan Zhang;Chuanlin Ding;Diego Elias Montoya-Durango

  • Tumor Exosomes Inhibit Differentiation of Bone Marrow Dendritic Cells

    Shaohua Yu;Cunren Liu;Kaihong Su;Jianhua Wang

  • MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

    Yun Teng;Yi Ren;Xin Hu;Xin Hu;Jingyao Mu

  • Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

    Qilong Wang;Xiaoying Zhuang;Jingyao Mu;Zhong-Bin Deng

  • Exosomes: A Novel Pathway of Local and Distant Intercellular Communication that Facilitates the Growth and Metastasis of Neoplastic Lesions

    Huang-Ge Zhang;William E. Grizzle

  • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host

    Cunren Liu;Shaohua Yu;John Kappes;Jianhua Wang

  • Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase

    Zhongbin Deng;Yuan Rong;Yun Teng;Jingyao Mu

  • Exosomes and Cancer: A Newly Described Pathway of Immune Suppression

    Huang-Ge Zhang;William E. Grizzle

  • Regulation of apoptosis proteins in cancer cells by ubiquitin

    Huang-Ge Zhang;Jianhua Wang;Xinwen Yang;Hui-Chen Hsu

Frequent Co-Authors

John D. Mountz
John D. Mountz University of Alabama at Birmingham
Jun Yan
Jun Yan University of Louisville
William E. Grizzle
William E. Grizzle University of Alabama at Birmingham
Donald R. Miller
Donald R. Miller University of Louisville
Tong Zhou
Tong Zhou University of Alabama at Birmingham
David T. Curiel
David T. Curiel Washington University in St. Louis
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham
Craig J. McClain
Craig J. McClain University of Louisville
Xiang Zhang
Xiang Zhang University of Louisville
Stephen Barnes
Stephen Barnes University of Alabama at Birmingham

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Related Online Degrees & Career Pathways

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