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Medicine

D-Index
116
Citations
59308
World Ranking
4304
National Ranking
2351

Overview

William E. Grizzle is affiliated with the University of Alabama at Birmingham in the United States. Their research activity spans multiple fields including biochemistry, genetics and molecular biology, medicine, and engineering, with a particular focus on biomedical engineering, cancer research, molecular biology, oncology, and pulmonary and respiratory medicine.

The scientist's work encompasses a range of topics centered on cancer theranostics, imaging techniques, cancer diagnostics, and drug delivery systems. Key thematic areas include:

  • Nanoplatforms for cancer theranostics
  • Photoacoustic and ultrasonic imaging
  • Cancer genomics and diagnostics
  • Breast cancer treatment studies
  • Nanoparticle-based drug delivery
  • Extracellular vesicles in disease
  • Advanced nanomaterials in catalysis

William E. Grizzle has contributed to numerous peer-reviewed papers, including the following selected publications:

  • Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations, 2020, published in Cancers
  • Toxicity Assessment of Mesoporous Silica Nanoparticles upon Intravenous Injection in Mice: Implications for Drug Delivery, 2022, published in Pharmaceutics
  • Active Targeting Significantly Outperforms Nanoparticle Size in Facilitating Tumor-Specific Uptake in Orthotopic Pancreatic Cancer, 2021, published in ACS Applied Materials & Interfaces
  • Diabetes, Obesity, and Inflammation: Impact on Clinical and Radiographic Features of Breast Cancer, 2021, published in International Journal of Molecular Sciences
  • Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression, 2020, published in Oncogene

Their research outputs have appeared frequently in journal venues such as Cancer Research, Cancers, Chem, Cancer Epidemiology Biomarkers & Prevention, and Biotechnic & Histochemistry. The distribution of publications highlights recurring contributions to Cancer Research and Cancers journals.

  • Cancer Research
  • Cancers
  • Chem
  • Cancer Epidemiology Biomarkers & Prevention
  • Biotechnic & Histochemistry

Collaboration has been an important aspect of their work, with frequent co-authors including Lacey R. McNally, William M. MacCuaig, Molly McNally, Ajay N. Jain, and Clayton Yates, reflecting sustained interdisciplinary partnerships within the research community.

  • Lacey R. McNally
  • William M. MacCuaig
  • Molly McNally
  • Ajay N. Jain
  • Clayton Yates

Best Publications

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

    Dongmei Sun;Xiaoying Zhuang;Xiaoying Zhuang;Xiaoyu Xiang;Xiaoyu Xiang;Yuelong Liu

  • Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

    Xiaoying Zhuang;Xiaoyu Xiang;William Grizzle;Dongmei Sun

  • Detection of high incidence of K- ras oncogenes during human colon tumorigenesis

    Kathleen Forrester;Concepcion Almoguera;Kyuhyung Han;Kyuhyung Han;William E. Grizzle

  • The national lung screening trial: Overview and study design

    Constantine A. Gatsonis;Denise R. Aberle;Christine D. Berg;William C. Black

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Induction of myeloid-derived suppressor cells by tumor exosomes

    Xiaoyu Xiang;Anton Poliakov;Cunren Liu;Yuelong Liu

  • Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group.

    Melissa K. Tuck;Daniel W. Chan;David Chia;Andrew K. Godwin

  • Modern age pathology of pulmonary arterial hypertension.

    Elvira Stacher;Brian B. Graham;James M. Hunt;Aneta Gandjeva

  • Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function

    Cunren Liu;Shaohua Yu;Kurt Zinn;Jianhua Wang

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • SIRT1 Is Significantly Elevated in Mouse and Human Prostate Cancer

    Derek M. Huffman;William E. Grizzle;Marcas M. Bamman;Marcas M. Bamman;Jeong Su Kim;Jeong Su Kim

  • Tumor Exosomes Inhibit Differentiation of Bone Marrow Dendritic Cells

    Shaohua Yu;Cunren Liu;Kaihong Su;Jianhua Wang

  • Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance

    Zhong-Bin Deng;Anton Poliakov;Robert W. Hardy;Ronald H. Clements

  • Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.

    Robert Bookstein;Pascale Rio;Steven A. Madreperla;Frank Hong

  • Exosomes: A Novel Pathway of Local and Distant Intercellular Communication that Facilitates the Growth and Metastasis of Neoplastic Lesions

    Huang-Ge Zhang;William E. Grizzle

  • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host

    Cunren Liu;Shaohua Yu;John Kappes;Jianhua Wang

Frequent Co-Authors

Huang-Ge Zhang
Huang-Ge Zhang University of Louisville
Heidi L. Weiss
Heidi L. Weiss University of Kentucky
Albert F. LoBuglio
Albert F. LoBuglio University of Alabama at Birmingham
Ronald D. Alvarez
Ronald D. Alvarez Vanderbilt University Medical Center
David T. Curiel
David T. Curiel Washington University in St. Louis
Ajay P. Singh
Ajay P. Singh University of South Alabama
John D. Mountz
John D. Mountz University of Alabama at Birmingham
Gene P. Siegal
Gene P. Siegal University of Alabama at Birmingham
Jeffrey Schlom
Jeffrey Schlom National Institutes of Health
Tong Zhou
Tong Zhou University of Alabama at Birmingham

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