D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 54 Citations 8,171 109 World Ranking 1677 National Ranking 107

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Immune system

The scientist’s investigation covers issues in Factor H, Complement system, Immunology, Complement C3b Inactivator Proteins and Atypical hemolytic uremic syndrome. Her Factor H research incorporates themes from Complement factor I, Borrelia burgdorferi and Molecular biology. The Complement factor I study combines topics in areas such as Complement factor B and CD46.

Her work deals with themes such as Penetrance, Innate immune system and Glomerulonephritis, which intersect with Complement system. Her Immunology study which covers Gene that intersects with Etiology. As a member of one scientific family, Christine Skerka mostly works in the field of Complement C3b Inactivator Proteins, focusing on Microbiology and, on occasion, Immune system.

Her most cited work include:

  • Complement regulators and inhibitory proteins. (865 citations)
  • Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency (285 citations)
  • The Molecular Basis of Familial Hemolytic Uremic Syndrome: Mutation Analysis of Factor H Gene Reveals a Hot Spot in Short Consensus Repeat 20 (262 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Factor H, Complement system, Microbiology, Immunology and Alternative complement pathway. Her Factor H study incorporates themes from Complement factor I and Molecular biology. Her Complement system study combines topics in areas such as Plasma protein binding and Cell biology.

Her Microbiology research includes themes of Innate immune system, Immune system, Borrelia burgdorferi and Complement. Her Immunology study frequently draws connections to adjacent fields such as Gene. Her Complement component 2 study integrates concerns from other disciplines, such as Complement control protein, CD46, Complement factor B and Complement membrane attack complex.

She most often published in these fields:

  • Factor H (44.93%)
  • Complement system (38.16%)
  • Microbiology (32.85%)

What were the highlights of her more recent work (between 2016-2021)?

  • Complement system (38.16%)
  • Immunology (27.54%)
  • Factor H (44.93%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Complement system, Immunology, Factor H, Immune system and Cell biology. Her Complement system research focuses on Alternative complement pathway in particular. As a part of the same scientific family, she mostly works in the field of Immunology, focusing on Glomerulopathy and, on occasion, Atypical hemolytic uremic syndrome, Vasculitis and Context.

Her Factor H study is focused on Genetics in general. The concepts of her Immune system study are interwoven with issues in Computational biology, Gene, Virulence and Candida albicans. Her studies deal with areas such as Receptor, FOXP3, Cytokine and Complement as well as Cell biology.

Between 2016 and 2021, her most popular works were:

  • ApoE attenuates unresolvable inflammation by complex formation with activated C1q (86 citations)
  • Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator (43 citations)
  • Kallikrein Cleaves C3 and Activates Complement. (40 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

The scientist’s investigation covers issues in Complement system, Immunology, Microbiology, Cell biology and Plasmin. Christine Skerka works in the field of Complement system, focusing on Complement factor B in particular. She has researched Immunology in several fields, including Lupus nephritis, Membranoproliferative glomerulonephritis, Membranous nephropathy and Transcriptome.

Her work in the fields of Microbiology, such as Corpus albicans, intersects with other areas such as CD16. Her Cell biology research is multidisciplinary, incorporating perspectives in Alternative complement pathway, C3-convertase, Cytokine and FOXP3. Her Plasmin study combines topics from a wide range of disciplines, such as Cell, Phagocytosis, Aspergillus fumigatus, Cell damage and Plasminogen activator.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Complement regulators and inhibitory proteins.

Peter F. Zipfel;Peter F. Zipfel;Christine Skerka.
Nature Reviews Immunology (2009)

1195 Citations

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency

Mihály Józsi;Christoph Licht;Stefanie Strobel;Svante L. H. Zipfel.
Blood (2008)

351 Citations

Deletion of Complement Factor H–Related Genes CFHR1 and CFHR3 Is Associated with Atypical Hemolytic Uremic Syndrome

Peter F Zipfel;Matthew Edey;Stefan Heinen;Mihály Józsi.
PLOS Genetics (2007)

337 Citations

The Molecular Basis of Familial Hemolytic Uremic Syndrome: Mutation Analysis of Factor H Gene Reveals a Hot Spot in Short Consensus Repeat 20

Jessica Caprioli;Paola Bettinaglio;Peter F. Zipfel;Barbara Amadei.
Journal of The American Society of Nephrology (2001)

315 Citations

Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins

Peter Kraiczy;Jens Hellwage;Christine Skerka;Heiko Becker.
Journal of Biological Chemistry (2004)

312 Citations

Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and Factor H.

Peter Kraiczy;Christine Skerka;Michael Kirschfink;Volker Brade.
European Journal of Immunology (2001)

307 Citations

Factor H–related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation

Stefan Heinen;Andrea Hartmann;Nadine Lauer;Ulrike Wiehl.
Blood (2009)

297 Citations

Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countries

H P H Neumann;M Salzmann;B Bohnert-Iwan;T Mannuelian.
Journal of Medical Genetics (2003)

291 Citations

Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)

Maria Asuncion Abrera-Abeleda;Carla Nishimura;Jenna L.H. Smith;Sanjjev Sethi.
Journal of Medical Genetics (2005)

285 Citations

Complement and diseases: defective alternative pathway control results in kidney and eye diseases.

Peter F. Zipfel;Stefan Heinen;Mihály Józsi;Christine Skerka.
Molecular Immunology (2006)

280 Citations

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