The scientist’s investigation covers issues in Factor H, Complement system, Immunology, Complement C3b Inactivator Proteins and Atypical hemolytic uremic syndrome. Her Factor H research incorporates themes from Complement factor I, Borrelia burgdorferi and Molecular biology. The Complement factor I study combines topics in areas such as Complement factor B and CD46.
Her work deals with themes such as Penetrance, Innate immune system and Glomerulonephritis, which intersect with Complement system. Her Immunology study which covers Gene that intersects with Etiology. As a member of one scientific family, Christine Skerka mostly works in the field of Complement C3b Inactivator Proteins, focusing on Microbiology and, on occasion, Immune system.
Her primary areas of investigation include Factor H, Complement system, Microbiology, Immunology and Alternative complement pathway. Her Factor H study incorporates themes from Complement factor I and Molecular biology. Her Complement system study combines topics in areas such as Plasma protein binding and Cell biology.
Her Microbiology research includes themes of Innate immune system, Immune system, Borrelia burgdorferi and Complement. Her Immunology study frequently draws connections to adjacent fields such as Gene. Her Complement component 2 study integrates concerns from other disciplines, such as Complement control protein, CD46, Complement factor B and Complement membrane attack complex.
Her primary scientific interests are in Complement system, Immunology, Factor H, Immune system and Cell biology. Her Complement system research focuses on Alternative complement pathway in particular. As a part of the same scientific family, she mostly works in the field of Immunology, focusing on Glomerulopathy and, on occasion, Atypical hemolytic uremic syndrome, Vasculitis and Context.
Her Factor H study is focused on Genetics in general. The concepts of her Immune system study are interwoven with issues in Computational biology, Gene, Virulence and Candida albicans. Her studies deal with areas such as Receptor, FOXP3, Cytokine and Complement as well as Cell biology.
The scientist’s investigation covers issues in Complement system, Immunology, Microbiology, Cell biology and Plasmin. Christine Skerka works in the field of Complement system, focusing on Complement factor B in particular. She has researched Immunology in several fields, including Lupus nephritis, Membranoproliferative glomerulonephritis, Membranous nephropathy and Transcriptome.
Her work in the fields of Microbiology, such as Corpus albicans, intersects with other areas such as CD16. Her Cell biology research is multidisciplinary, incorporating perspectives in Alternative complement pathway, C3-convertase, Cytokine and FOXP3. Her Plasmin study combines topics from a wide range of disciplines, such as Cell, Phagocytosis, Aspergillus fumigatus, Cell damage and Plasminogen activator.
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Complement regulators and inhibitory proteins.
Peter F. Zipfel;Peter F. Zipfel;Christine Skerka.
Nature Reviews Immunology (2009)
Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency
Mihály Józsi;Christoph Licht;Stefanie Strobel;Svante L. H. Zipfel.
Deletion of Complement Factor H–Related Genes CFHR1 and CFHR3 Is Associated with Atypical Hemolytic Uremic Syndrome
Peter F Zipfel;Matthew Edey;Stefan Heinen;Mihály Józsi.
PLOS Genetics (2007)
The Molecular Basis of Familial Hemolytic Uremic Syndrome: Mutation Analysis of Factor H Gene Reveals a Hot Spot in Short Consensus Repeat 20
Jessica Caprioli;Paola Bettinaglio;Peter F. Zipfel;Barbara Amadei.
Journal of The American Society of Nephrology (2001)
Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins
Peter Kraiczy;Jens Hellwage;Christine Skerka;Heiko Becker.
Journal of Biological Chemistry (2004)
Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and Factor H.
Peter Kraiczy;Christine Skerka;Michael Kirschfink;Volker Brade.
European Journal of Immunology (2001)
Factor H–related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
Stefan Heinen;Andrea Hartmann;Nadine Lauer;Ulrike Wiehl.
Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countries
H P H Neumann;M Salzmann;B Bohnert-Iwan;T Mannuelian.
Journal of Medical Genetics (2003)
Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)
Maria Asuncion Abrera-Abeleda;Carla Nishimura;Jenna L.H. Smith;Sanjjev Sethi.
Journal of Medical Genetics (2005)
Complement and diseases: defective alternative pathway control results in kidney and eye diseases.
Peter F. Zipfel;Stefan Heinen;Mihály Józsi;Christine Skerka.
Molecular Immunology (2006)
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