His primary scientific interests are in Borrelia burgdorferi, Microbiology, Cell biology, Virology and Factor H. Particularly relevant to Borrelia is his body of work in Borrelia burgdorferi. His Microbiology research integrates issues from Fibronectin, Plasma protein binding, Complement system and Plasminogen activator.
His Cell biology research is multidisciplinary, relying on both Perforin, Jurkat cells, Chemokine and GZMB. His studies deal with areas such as Humoral immunity, Antibody, Antigen and Spirochaetaceae as well as Virology. His Factor H study combines topics in areas such as Complement factor I, Complement factor B, Biochemistry, Binding site and Molecular biology.
Reinhard Wallich spends much of his time researching Borrelia burgdorferi, Microbiology, Virology, Factor H and Cell biology. Reinhard Wallich combines subjects such as Lyme disease, Pathogen and Antigen with his study of Borrelia burgdorferi. His research integrates issues of Alternative complement pathway, Borrelia, Immune system and Complement in his study of Microbiology.
His research in Virology intersects with topics in Recombinant DNA, Humoral immunity, Borrelia Burgdorferi Infection, Epitope and Innate immune system. Reinhard Wallich has researched Factor H in several fields, including Complement factor I and Complement factor B. The concepts of his Cell biology study are interwoven with issues in Cytotoxic T cell, Granzyme B, Granzyme K, GZMB and Molecular biology.
Reinhard Wallich mostly deals with Microbiology, Cell biology, Immune system, Borrelia burgdorferi and Complement system. The various areas that he examines in his Microbiology study include Complement, Plasma protein binding, Borrelia, Lyme disease and Binding site. In his research on the topic of Cell biology, Complement receptor is strongly related with Classical complement pathway.
His Immune system research also works with subjects such as
His primary areas of investigation include Complement system, Microbiology, Factor H, Cell biology and Borrelia burgdorferi. His Complement system study incorporates themes from Innate immune system, Glycoprotein and Candida albicans. The Microbiology study combines topics in areas such as Plasminogen activator, Complement component 5, Vitronectin and Plasma protein binding.
His studies examine the connections between Factor H and genetics, as well as such issues in Complement factor B, with regards to C3-convertase, Alternative complement pathway, Complement factor I and Virology. His study in Cell biology is interdisciplinary in nature, drawing from both Granzyme K, Secretion, Lymphocytic choriomeningitis, Granzyme and Virus. His Borrelia burgdorferi research includes elements of Recombinant DNA, Kringle domain, Immune system, Function and Lyme disease.
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Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes.
Gabriele Köllisch;Behnam Naderi Kalali;Verena Voelcker;Reinhard Wallich.
Immunology (2005)
Factor H–related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
Stefan Heinen;Andrea Hartmann;Nadine Lauer;Ulrike Wiehl.
Blood (2009)
Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins
Peter Kraiczy;Jens Hellwage;Christine Skerka;Heiko Becker.
Journal of Biological Chemistry (2004)
Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response
Sunil S. Metkar;Cheikh Menaa;Julian Pardo;Julian Pardo;Baikun Wang.
Immunity (2008)
The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor
Hans Fuchs;Reinhard Wallich;Markus M. Simon;Michael D. Kramer.
Proceedings of the National Academy of Sciences of the United States of America (1994)
An Avian Reservoir (Turdus merula) of the Lyme Borreliosis Spirochetes
Pierre-Françcois Humair;Danièle Postic;Reinhard Wallich;Lise Gern.
Zentralblatt Fur Bakteriologie-international Journal of Medical Microbiology Virology Parasitology and Infectious Diseases (1998)
Recombinant Outer Surface Protein A from Borrelia burgdorferi Induces Antibodies Protective against Spirochetal Infection in Mice
Markus M. Simon;Ulrich E. Schaible;Michael D. Kramer;Christoph Eckerskorn.
The Journal of Infectious Diseases (1991)
Apoptotic Pathways Are Selectively Activated by Granzyme A and/or Granzyme B in CTL-mediated Target Cell Lysis
Julián Pardo;Alberto Bosque;Reina Brehm;Reinhard Wallich.
Journal of Cell Biology (2004)
Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family
Peter Kraiczy;Jens Hellwage;Christine Skerka;Michael Kirschfink.
European Journal of Immunology (2003)
Functional characterization of BbCRASP-2, a distinct outer membrane protein of Borrelia burgdorferi that binds host complement regulators factor H and FHL-1.
Kristina Hartmann;Carsten Corvey;Christine Skerka;Michael Kirschfink.
Molecular Microbiology (2006)
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