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Microbiology

D-Index
51
Citations
7148
World Ranking
4374
National Ranking
1690

Overview

Richard T. Marconi is affiliated with Virginia Commonwealth University Medical Center in the United States. Their research primarily focuses on vector-borne infectious diseases, with particular attention to Lyme disease and related topics within immunology, microbiology, and medicine.

The main fields of study in their work include:

  • Medicine
  • Immunology and Microbiology

Their subfields of study cover:

  • Parasitology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • Ecology, Evolution, Behavior and Systematics
  • Insect Science

Main topics addressed in Marconi's research encompass:

  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Vector-Borne Animal Diseases
  • Mosquito-borne diseases and control
  • Insect symbiosis and bacterial influences
  • Oral microbiology and periodontitis research
  • Toxin Mechanisms and Immunotoxins

Their recent representative papers include:

  • Recent Progress in Lyme Disease and Remaining Challenges, 2021, Frontiers in Medicine
  • Human and Veterinary Vaccines for Lyme Disease, 2020, Current Issues in Molecular Biology
  • Development and Optimization of OspC Chimeritope Vaccinogens for Lyme Disease, 2020, Vaccine
  • VANGUARD®crLyme: A Next Generation Lyme Disease Vaccine That Prevents B. burgdorferi Infection in Dogs, 2020, Vaccine X
  • Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection, 2020, mBio

They have published extensively in several venues, with frequent contributions to:

  • mBio
  • Infection and Immunity
  • Vaccine X
  • Molecular Oral Microbiology
  • bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors who have collaborated with Marconi include:

  • Nathaniel S. O'Bier
  • Dhara Patel
  • Edward J. A. Schuler
  • Andrew C. Camire
  • Jason A. Carlyon

Best Publications

  • Development of polymerase chain reaction primer sets for diagnosis of Lyme disease and for species-specific identification of Lyme disease isolates by 16S rRNA signature nucleotide analysis.

    R T Marconi;C F Garon

  • Identification of novel insertion elements, restriction fragment length polymorphism patterns, and discontinuous 23S rRNA in Lyme disease spirochetes: phylogenetic analyses of rRNA genes and their intergenic spacers in Borrelia japonica sp. nov. and genomic group 21038 (Borrelia andersonii sp. nov.) isolates.

    R T Marconi;D Liveris;I Schwartz

  • Transcriptional analyses and mapping of the ospC gene in Lyme disease spirochetes.

    R T Marconi;D S Samuels;C F Garon

  • Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions.

    Elizabeth A. Rogers;Darya Terekhova;Hong-Ming Zhang;Kelley M. Hovis

  • Demonstration of OspC Type Diversity in Invasive Human Lyme Disease Isolates and Identification of Previously Uncharacterized Epitopes That Define the Specificity of the OspC Murine Antibody Response

    Christopher G. Earnhart;Eric L. Buckles;John Stephen Dumler;Richard T. Marconi

  • Comprehensive analysis of the factor H binding capabilities of Borrelia species associated with Lyme disease: Delineation of two distinct classes of factor H binding proteins

    John V. McDowell;Jill Wolfgang;Emily Tran;Michael S. Metts

  • Analysis of the OspE Determinants Involved in Binding of Factor H and OspE-Targeting Antibodies Elicited during Borrelia burgdorferi Infection in Mice

    Michael S. Metts;John V. McDowell;Michael Theisen;Paul Robert Hansen

  • Phylogenetic analysis of the genus Borrelia: a comparison of North American and European isolates of Borrelia burgdorferi.

    R T Marconi;C F Garon

  • Recent Progress in Lyme Disease and Remaining Challenges.

    Jason R. Bobe;Brandon L. Jutras;Elizabeth J. Horn;Monica E. Embers

  • Microbes bind complement inhibitor factor H via a common site.

    T. Meri;H. Amdahl;M. J. Lehtinen;Satu Hyvärinen

  • Evidence that the variable regions of the central domain of VlsE are antigenic during infection with lyme disease spirochetes.

    John V. McDowell;Shian Ying Sung;Linden T. Hu;Richard T. Marconi

  • Identification and Characterization of a Linear-Plasmid-Encoded Factor H-Binding Protein (FhbA) of the Relapsing Fever Spirochete Borrelia hermsii

    Kelley M. Hovis;John V. McDowell;LaToya Griffin;Richard T. Marconi

  • Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strains.

    Christopher G. Earnhart;Eric L. Buckles;Richard T. Marconi

  • The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes.

    Jessica L. Kostick;Lee T. Szkotnicki;Elizabeth A. Rogers;Paola Bocci

  • Variability of osp genes and gene products among species of Lyme disease spirochetes.

    R T Marconi;M E Konkel;C F Garon

  • Molecular and evolutionary analyses of a variable series of genes in Borrelia burgdorferi that are related to ospE and ospF, constitute a gene family, and share a common upstream homology box.

    Richard T. Marconi;Shian Ying Sung;Carrie A Norton Hughes;Jason A. Carlyon

  • Identification of a third genomic group of Borrelia burgdorferi through signature nucleotide analysis and 16S rRNA sequence determination.

    Richard T. Marconi;Claude F. Garon

  • Analysis of the distribution and molecular heterogeneity of the ospD gene among the Lyme disease spirochetes: evidence for lateral gene exchange.

    R T Marconi;D S Samuels;R K Landry;C F Garon

  • An Octavalent Lyme Disease Vaccine Induces Antibodies That Recognize All Incorporated ospC Type-Specific Sequences

    Christopher G. Earnhart;Richard T. Marconi

  • Selective Binding of Borrelia burgdorferi OspE Paralogs to Factor H and Serum Proteins from Diverse Animals: Possible Expansion of the Role of OspE in Lyme Disease Pathogenesis

    Kelley M. Hovis;Emily Tran;Christina M. Sundy;Eric Buckles

Frequent Co-Authors

Michael Theisen
Michael Theisen University of Copenhagen
Seppo Meri
Seppo Meri University of Helsinki
David L. Gordon
David L. Gordon Flinders Medical Centre
Allen L. Richards
Allen L. Richards Naval Medical Research Center
Melissa J. Caimano
Melissa J. Caimano University of Connecticut Health Center
Claude F. Garon
Claude F. Garon National Institutes of Health
Ira Schwartz
Ira Schwartz New York Medical College
Justin D. Radolf
Justin D. Radolf University of Connecticut Health Center
Michael E. Konkel
Michael E. Konkel Washington State University
Daniel H. Conrad
Daniel H. Conrad Virginia Commonwealth University

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