D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 79 Citations 17,791 225 World Ranking 681 National Ranking 396
Medicine D-index 83 Citations 18,962 240 World Ranking 8204 National Ranking 4470

Research.com Recognitions

Awards & Achievements

2016 - Fellow of the American Association for the Advancement of Science (AAAS)

2016 - Fellow of the American Association for the Advancement of Science (AAAS)

2013 - Fellow, National Academy of Inventors

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antibody

His scientific interests lie mostly in Streptococcus pneumoniae, Microbiology, Pneumococcal infections, Immunology and Virology. His Streptococcus pneumoniae study incorporates themes from Virulence factor, Serotype and Immunization. His Microbiology research includes elements of Antibody, Mutant, Antigen and Virulence.

His research in Pneumococcal infections intersects with topics in Protein A, Toxoid, Vaccination, Genetically modified mouse and C-reactive protein. David E. Briles combines subjects such as Carriage and Pneumococcal pneumonia with his study of Immunology. David E. Briles has researched Virology in several fields, including Cross immunity, Cholera toxin and Pneumonia.

His most cited work include:

  • ANTIPHOSPHOCHOLINE ANTIBODIES FOUND IN NORMAL MOUSE SERUM ARE PROTECTIVE AGAINST INTRAVENOUS INFECTION WITH TYPE 3 STREPTOCOCCUS PNEUMONIAE (420 citations)
  • Subclass restriction of murine anti-carbohydrate antibodies. (371 citations)
  • Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae. (301 citations)

What are the main themes of his work throughout his whole career to date?

Microbiology, Streptococcus pneumoniae, Immunology, Antibody and Virology are his primary areas of study. His Microbiology study combines topics in areas such as Recombinant DNA, Salmonella, Bacteria, Epitope and Virulence. His Streptococcus pneumoniae research includes themes of Serotype, Immunity and Streptococcaceae.

His studies deal with areas such as Pneumococcal pneumonia and Pneumonia as well as Immunology. His Antibody research is multidisciplinary, incorporating perspectives in Molecular biology and Antigen. His studies in Virology integrate themes in fields like Antiserum, Serology and Conjugate vaccine.

He most often published in these fields:

  • Microbiology (62.29%)
  • Streptococcus pneumoniae (60.29%)
  • Immunology (40.29%)

What were the highlights of his more recent work (between 2011-2021)?

  • Streptococcus pneumoniae (60.29%)
  • Microbiology (62.29%)
  • Immunology (40.29%)

In recent papers he was focusing on the following fields of study:

David E. Briles mostly deals with Streptococcus pneumoniae, Microbiology, Immunology, Virology and Antibody. His Streptococcus pneumoniae research integrates issues from Immunization, Antigen, Serotype and Immunity. He is interested in Pneumococcal infections, which is a field of Microbiology.

His work deals with themes such as Bronchoalveolar lavage, Respiratory tract and Pneumococcal pneumonia, which intersect with Immunology. His work in Virology covers topics such as Conjugate vaccine which are related to areas like Salmonella typhi. In Antibody, David E. Briles works on issues like In vitro, which are connected to Vaccine efficacy.

Between 2011 and 2021, his most popular works were:

  • Nanogel-Based PspA Intranasal Vaccine Prevents Invasive Disease and Nasal Colonization by Streptococcus pneumoniae (91 citations)
  • Nontypeable Pneumococci Can Be Divided into Multiple cps Types, Including One Type Expressing the Novel Gene pspK (77 citations)
  • Specific immunization strategies against oxidized low‐density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice (66 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

David E. Briles mainly investigates Microbiology, Streptococcus pneumoniae, Virology, Antibody and Pneumococcal infections. His study in Microbiology is interdisciplinary in nature, drawing from both Virulence factor, Virulence, Recombinant DNA, Mutant and Alveolar macrophage. His study explores the link between Streptococcus pneumoniae and topics such as Immunology that cross with problems in Scavenger receptor and Pneumonia.

His research in Virology tackles topics such as Antigen which are related to areas like Pneumococcal disease, Conserved sequence and Germline. His Antibody research is multidisciplinary, relying on both Phosphorylcholine, Peptide sequence, Gene and Frameshift mutation. The concepts of his Pneumococcal infections study are interwoven with issues in Opsonin Proteins and Immunoglobulin G.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

ANTIPHOSPHOCHOLINE ANTIBODIES FOUND IN NORMAL MOUSE SERUM ARE PROTECTIVE AGAINST INTRAVENOUS INFECTION WITH TYPE 3 STREPTOCOCCUS PNEUMONIAE

David E. Briles;Moon Nahm;Kenneth Schroer;Joseph Davie.
Journal of Experimental Medicine (1981)

541 Citations

Subclass restriction of murine anti-carbohydrate antibodies.

R M Perlmutter;D Hansburg;D E Briles;R A Nicolotti.
Journal of Immunology (1978)

518 Citations

Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.

A M Berry;J Yother;D E Briles;D Hansman.
Infection and Immunity (1989)

410 Citations

Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae

Susan K. Hollingshead;Robert Becker;David E. Briles.
Infection and Immunity (2000)

375 Citations

Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae

Anh-Hue T. Tu;Robert L. Fulgham;Mark A. McCrory;David E. Briles.
Infection and Immunity (1999)

366 Citations

Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.

David E. Briles;Eddie Ades;James C. Paton;Jacquelyn S. Sampson.
Infection and Immunity (2000)

360 Citations

Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.

D E Briles;C Forman;S Hudak;J L Claflin.
Journal of Experimental Medicine (1982)

360 Citations

Immunization of Humans with Recombinant Pneumococcal Surface Protein A (rPspA) Elicits Antibodies That Passively Protect Mice from Fatal Infection with Streptococcus pneumoniae Bearing Heterologous PspA

David E. Briles;Susan K. Hollingshead;Janice King;Amy Swift.
The Journal of Infectious Diseases (2000)

353 Citations

The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia.

Alexis Brooks-Walter;David E. Briles;Susan K. Hollingshead.
Infection and Immunity (1999)

316 Citations

Basophils enhance immunological memory responses.

Andrea Denzel;Ulrich A Maus;Manuel Rodriguez Gomez;Cordula Moll;Cordula Moll.
Nature Immunology (2008)

315 Citations

Editorial Boards

Vaccine
(Impact Factor: 4.169)

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