World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
97
Citations
26531
World Ranking
836
National Ranking
470

Medicine

D-Index
97
Citations
26714
World Ranking
9436
National Ranking
4868

David E. Briles publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where David E. Briles sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 345 publications — 73rd percentile

73% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

David E. Briles D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where David E. Briles sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 97 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2013 - Fellow, National Academy of Inventors

Overview

David E. Briles is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily focuses on medicine, with a significant emphasis on immunology and microbiology. The main subfields of study include epidemiology, microbiology, public health, environmental and occupational health, immunology, and molecular biology.

Their work extensively covers topics related to pneumonia and respiratory infections, bacterial infections and vaccines, respiratory viral infections research, streptococcal infections and treatments, influenza virus research studies, glycosylation and glycoproteins research, and Pneumocystis jirovecii pneumonia detection and treatment.

David E. Briles has contributed to a number of scientific papers, including the following recent publications:

  • A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci, 2021, Vaccine
  • Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza, 2021, Cell Reports
  • Streptococcus pneumoniae Binds to Host Lactate Dehydrogenase via PspA and PspC To Enhance Virulence, 2021, mBio
  • Characterization and Specification of a Trivalent Protein-Based Pneumococcal Vaccine Formulation Using an Adjuvant-Free Nanogel Nasal Delivery System, 2021, Molecular Pharmaceutics
  • A Jack of All Trades: The Role of Pneumococcal Surface Protein A in the Pathogenesis of Streptococcus pneumoniae, 2022, Frontiers in Cellular and Infection Microbiology

Frequent co-authors in their research include:

  • Carlos J. Orihuela (5 publications)
  • Yoshikazu Yuki (3 publications)
  • Shin-ichi Sawada (3 publications)
  • Reshmi Mukerji (3 publications)
  • Kazunari Akiyoshi (3 publications)

The scientist has published notably in journals such as:

  • mBio
  • The Pediatric Infectious Disease Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Vaccine

David E. Briles has been recognized with several awards, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2016 and a Fellow of the National Academy of Inventors in 2013.

Best Publications

  • ANTIPHOSPHOCHOLINE ANTIBODIES FOUND IN NORMAL MOUSE SERUM ARE PROTECTIVE AGAINST INTRAVENOUS INFECTION WITH TYPE 3 STREPTOCOCCUS PNEUMONIAE

    David E. Briles;Moon Nahm;Kenneth Schroer;Joseph Davie

  • Subclass restriction of murine anti-carbohydrate antibodies.

    R M Perlmutter;D Hansburg;D E Briles;R A Nicolotti

  • Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae

    Susan K. Hollingshead;Robert Becker;David E. Briles

  • Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.

    A M Berry;J Yother;D E Briles;D Hansman

  • Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae

    Anh-Hue T. Tu;Robert L. Fulgham;Mark A. McCrory;David E. Briles

  • Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.

    David E. Briles;Eddie Ades;James C. Paton;Jacquelyn S. Sampson

  • Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.

    D E Briles;C Forman;S Hudak;J L Claflin

  • Immunization of Humans with Recombinant Pneumococcal Surface Protein A (rPspA) Elicits Antibodies That Passively Protect Mice from Fatal Infection with Streptococcus pneumoniae Bearing Heterologous PspA

    David E. Briles;Susan K. Hollingshead;Janice King;Amy Swift

  • Basophils enhance immunological memory responses.

    Andrea Denzel;Ulrich A Maus;Manuel Rodriguez Gomez;Cordula Moll;Cordula Moll

  • Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae

    M. J. Crain;W. D. Waltman;J. S. Turner;J. Yother

  • Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae.

    D E Briles;M J Crain;B M Gray;C Forman

  • The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia.

    Alexis Brooks-Walter;David E. Briles;Susan K. Hollingshead

  • PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type.

    L S McDaniel;J S Sheffield;P Delucchi;D E Briles

  • Intranasal Immunization of Mice with PspA (Pneumococcal Surface Protein A) Can Prevent Intranasal Carriage, Pulmonary Infection, and Sepsis with Streptococcus pneumoniae

    Hong-Yin Wu;Moon H. Nahm;Y. Guo;Michael W. Russell

  • PspA Protects Streptococcus pneumoniae from Killing by Apolactoferrin, and Antibody to PspA Enhances Killing of Pneumococci by Apolactoferrin

    Mirza Shaper;Susan K. Hollingshead;William H. Benjamin;David E. Briles

  • HUMAN C-REACTIVE PROTEIN IS PROTECTIVE AGAINST FATAL STREPTOCOCCUS PNEUMONIAE INFECTION IN TRANSGENIC MICE

    A J Szalai;D E Briles;J E Volanakis

  • Immunizations with Pneumococcal Surface Protein A and Pneumolysin Are Protective against Pneumonia in a Murine Model of Pulmonary Infection with Streptococcus pneumoniae

    David E. Briles;Susan K. Hollingshead;James C. Paton;Edwin W. Ades

  • Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis.

    J Yother;D E Briles

  • Development of a Vaccine against Invasive Pneumococcal Disease Based on Combinations of Virulence Proteins of Streptococcus pneumoniae

    Abiodun D. Ogunniyi;Marcin Grabowicz;David E. Briles;Jan Cook

  • Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA).

    L S McDaniel;J Yother;M Vijayakumar;L McGarry

Frequent Co-Authors

Susan K. Hollingshead
Susan K. Hollingshead University of Alabama at Birmingham
Larry S. McDaniel
Larry S. McDaniel University of Mississippi Medical Center
Janet Yother
Janet Yother University of Alabama at Birmingham
William H. Benjamin
William H. Benjamin University of Alabama at Birmingham
James C. Paton
James C. Paton University of Adelaide
Moon H. Nahm
Moon H. Nahm University of Alabama at Birmingham
Joseph M. Davie
Joseph M. Davie Pfizer (Germany)
Alexander J. Szalai
Alexander J. Szalai University of Alabama at Birmingham
John F. Kearney
John F. Kearney University of Alabama at Birmingham
Hiroshi Kiyono
Hiroshi Kiyono University of Tokyo

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