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Immunology

D-Index
61
Citations
13337
World Ranking
3238
National Ranking
1513

Overview

Richard Malley is affiliated with Boston Children's Hospital in the United States and has focused primarily on research in Medicine with particular attention to Epidemiology, Infectious Diseases, and Microbiology. Their work also extends into Public Health, Environmental and Occupational Health, and Molecular Biology.

The main topics of Malley's research encompass Pneumonia and Respiratory Infections, Respiratory viral infections, Bacterial Infections and Vaccines, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Pneumocystis jirovecii pneumonia detection and treatment, and Viral gastroenteritis research and epidemiology.

Frequent publication venues where Malley's research appears include Vaccine, Vaccines, bioRxiv (Cold Spring Harbor Laboratory), Clinical Infectious Diseases, and mBio.

Recent papers authored or coauthored by Malley include:

  • Post-COVID-19 Conditions Among Children 90 Days After SARS-CoV-2 Infection, 2022, JAMA Network Open
  • Fostering healthy aging: The interdependency of infections, immunity and frailty, 2021, Ageing Research Reviews
  • Phase 1/2 study of a novel 24-valent pneumococcal vaccine in healthy adults aged 18 to 64 years and in older adults aged 65 to 85 years, 2022, Vaccine
  • Overview of the Nontyphoidal and Paratyphoidal Salmonella Vaccine Pipeline: Current Status and Future Prospects, 2020, Clinical Infectious Diseases
  • Outcomes of SARS-CoV-2-Positive Youths Tested in Emergency Departments, 2022, JAMA Network Open

Coauthors who frequently collaborate with Malley include Ying-Jie Lu, Amy C. Plint, Anna Funk, Nathan Kuppermann, and Todd A. Florin.

Best Publications

  • Serotype replacement in disease after pneumococcal vaccination

    Daniel M Weinberger;Richard Malley;Marc Lipsitch

  • Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection.

    Richard Malley;Philipp Henneke;Sarah C. Morse;Michael J. Cieslewicz

  • Interleukin-17A Mediates Acquired Immunity to Pneumococcal Colonization

    Ying-Jie Lu;Jane Gross;Debby Bogaert;Adam Finn

  • CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization

    Richard Malley;Krzysztof Trzcinski;Amit Srivastava;Claudette M. Thompson

  • Pneumococcal Capsular Polysaccharide Structure Predicts Serotype Prevalence

    Daniel M. Weinberger;Krzysztof Trzciński;Ying-Jie Lu;Debby Bogaert

  • Reduction of Respiratory Syncytial Virus (RSV) in Tracheal Aspirates in Intubated Infants by Use of Humanized Monoclonal Antibody to RSV F Protein

    Richard Malley;John DeVincenzo;Octavio Ramilo;Penelope H. Dennehy

  • TH17-Based Vaccine Design for Prevention of Streptococcus pneumoniae Colonization

    Kristin L. Moffitt;Todd M. Gierahn;Ying-jie Lu;Paulo Gouveia

  • Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis.

    Lise E. Nigrovic;Richard Malley;Charles G. Macias;John T. Kanegaye

  • Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era.

    Lise E. Nigrovic;Nathan Kuppermann;Richard Malley

  • Interference between Streptococcus pneumoniae and Staphylococcus aureus: In Vitro Hydrogen Peroxide-Mediated Killing by Streptococcus pneumoniae

    Gili Regev-Yochay;Krzysztof Trzciński;Claudette M. Thompson;Richard Malley

  • The Apoptotic Response to Pneumolysin Is Toll-Like Receptor 4 Dependent and Protects against Pneumococcal Disease

    Amit Srivastava;Philipp Henneke;Alberto Visintin;Sarah C. Morse

  • Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci.

    Richard Malley;Marc Lipsitch;Anne Stack;Richard Saladino

  • Antibody-Independent, Interleukin-17A-Mediated, Cross-Serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide

    Richard Malley;Amit Srivastava;Marc Lipsitch;Claudette M. Thompson

  • Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

    Philipp Henneke;Philipp Henneke;Osamu Takeuchi;Richard Malley;Egil Lien

  • Are anticapsular antibodies the primary mechanism of protection against invasive pneumococcal disease

    Marc Lipsitch;Cynthia G Whitney;Elizabeth Zell;Tarja Kaijalainen

  • Epidemiologic Evidence for Serotype-Specific Acquired Immunity to Pneumococcal Carriage

    Daniel M. Weinberger;Ron Dagan;Noga Givon-Lavi;Gili Regev-Yochay

  • The classical lancefield antigen of group a streptococcus is a virulence determinant with implications for vaccine design

    Nina M. van Sorge;Nina M. van Sorge;Jason N. Cole;Jason N. Cole;Kirsten Kuipers;Anna Henningham

  • Next generation pneumococcal vaccines.

    Kristin L Moffitt;Richard Malley

  • Capsular Polysaccharide (CPS) Release by Serotype 3 Pneumococcal Strains Reduces the Protective Effect of Anti-Type 3 CPS Antibodies.

    Eun Hwa Choi;Fan Zhang;Ying Jie Lu;Richard Malley

  • Multiple antigen-presenting system (MAPS) to induce comprehensive B- and T-cell immunity

    Fan Zhang;Ying-Jie Lu;Richard Malley

  • Donor immunization with pneumococcal conjugate vaccine and early protective antibody responses following allogeneic hematopoietic cell transplantation.

    Deborah C. Molrine;Joseph H. Antin;Eva C. Guinan;Robert J. Soiffer

  • Antibody and cell-mediated immunity to Streptococcus pneumoniae: implications for vaccine development

    Richard Malley;Richard Malley

Frequent Co-Authors

Marc Lipsitch
Marc Lipsitch Harvard University
Krzysztof Trzciński
Krzysztof Trzciński Utrecht University
Adam Finn
Adam Finn University of Bristol
Mark R. Alderson
Mark R. Alderson Program for Appropriate Technology in Health
Ron Dagan
Ron Dagan Ben-Gurion University of the Negev
Douglas T. Golenbock
Douglas T. Golenbock University of Massachusetts Chan Medical School
Victor Nizet
Victor Nizet University of California, San Diego
John P. DeVincenzo
John P. DeVincenzo Middle Tennessee State University
Ethan Rubinstein
Ethan Rubinstein University of Manitoba
Nicholas J. Croucher
Nicholas J. Croucher Imperial College London

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