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Biology and Biochemistry

D-Index
65
Citations
15776
World Ranking
9122
National Ranking
659

Overview

Detlev Riesner is affiliated with Heinrich Heine University Düsseldorf in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. The scientist's work spans molecular biology, plant science, physiology, psychiatry and mental health, as well as health, toxicology, and mutagenesis.

The scientist has authored publications covering several topics, including advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, DNA and nucleic acid chemistry, RNA interference and gene delivery, Alzheimer's disease research and treatments, dementia and cognitive impairment research, and health, environment, and cognitive aging.

Recent papers authored or co-authored by Detlev Riesner include:

  • Time-resolved structural analysis of an RNA-cleaving DNA catalyst, 2021, Nature
  • Molecular Features and Metal Ions That Influence 10-23 DNAzyme Activity, 2020, Molecules
  • Development and Implementation of an Internal Quality Control Sample to Standardize Oligomer-Based Diagnostics of Alzheimer's Disease, 2023, Diagnostics
  • Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins, 2024, Viruses
  • The coming of age of DNA-based catalysts for therapeutic applications, 2025, Clinical and Translational Medicine

Frequent co-authors working alongside Riesner include Gerhard Steger, Manuel Etzkorn, Julian Victor, Hannah Rosenbach, and Christoph G. W. Gertzen.

The main venues where Detlev Riesner has published are:

  • Nature
  • Molecules
  • Diagnostics
  • Viruses
  • Clinical and Translational Medicine

Best Publications

  • Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures.

    Heinz L. Sanger;Gunther Klotz;Detlev Riesner;Hans J. Gross

  • Synthetic Mammalian Prions

    Giuseppe Legname;Ilia V. Baskakov;Hoang-Oanh B. Nguyen;Detlev Riesner

  • Temperature-gradient gel electrophoresis. Thermodynamic analysis of nucleic acids and proteins in purified form and in cellular extracts.

    Volker Rosenbaum;Detlev Riesner

  • Temperature-gradient gel electrophoresis of nucleic acids: analysis of conformational transitions, sequence variations, and protein-nucleic acid interactions.

    Detlev Riesner;Gerhard Steger;Rolf Zimmat;Robert A. Owens

  • Prion detection by an amyloid seeding assay.

    David W. Colby;Qiang Zhang;Shuyi Wang;Darlene Groth

  • Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice

    Andreas Muhs;David T Hickman;Maria Pihlgren;Nathalie Chuard

  • A two-dimensional electrophoretic technique for the detection of circular viroids and virusoids.

    Jürgen Schumacher;John W. Randles;Detlev Riesner

  • Apparatus for investigating fast chemical reactions by optical detection

    Leo C. M. De Maeyer;Carl-Roland Rabl;Thomas M. Jovin;Detlev Riesner

  • Intracellular re‐routing of prion protein prevents propagation of PrPSc and delays onset of prion disease

    Sabine Gilch;Konstanze F. Winklhofer;Martin H. Groschup;Max Nunziante

  • Viroid processing: switch from cleavage to ligation is driven by a change from a tetraloop to a loop E conformation

    Tilman Baumstark;Astrid R. W. Schrüder;Detlev Riesner

  • Mismatches in DNA double strands: thermodynamic parameters and their correlation to repair efficiencies

    Heinz Werntges;Gerhard Steger;Detlev Riesner;Hans-Joachim Fritz

  • Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry.

    Thomas R. Klein;Dieter Kirsch;Raimund Kaufmann;Detlev Riesner

  • Biochemistry and structure of PrPC and PrPSc

    Detlev Riesner

  • Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis

    Klaus Kellings;Norbert Meyer;Carol Mirenda;Stanley B. Prusiner

  • Search for a Prion-Specific Nucleic Acid

    Jiri G. Safar;Klaus Kellings;Ana Serban;Darlene Groth

  • VERFAHREN ZUR BESTIMMUNG VON $i(IN VITRO) AMPLIFIZIERTEN NUKLEINSÄUREN

    Manfred Eigen;Karsten Henco;Detlev Riesner

  • Imaging of viroids in nuclei from tomato leaf tissue by in situ hybridization and confocal laser scanning microscopy.

    J. Harders;N. Lukács;M. Robert-Nicoud;T. M. Jovin

  • Mechanisms of prion protein assembly into amyloid.

    Jan Stöhr;Nicole Weinmann;Holger Wille;Tina Kaimann

  • Diagnostic Procedure for Detection of Viroids and Viruses with Circular RNAs by “Return”–Gel Electrophoresis

    J. Schumacher;N. Meyer;D. Riesner;H. L. Weidemann

  • Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.

    D Riesner;K Kellings;K Post;H Wille

Frequent Co-Authors

Dieter Willbold
Dieter Willbold Forschungszentrum Jülich
Stanley B. Prusiner
Stanley B. Prusiner University of California, San Francisco
Thomas Schrader
Thomas Schrader University of Duisburg-Essen
Holger Wille
Holger Wille University of Alberta
Martin H. Groschup
Martin H. Groschup Friedrich-Loeffler-Institut
Darlene Groth
Darlene Groth University of California, San Francisco
Thomas M. Jovin
Thomas M. Jovin Max Planck Society
Jörg Tatzelt
Jörg Tatzelt Ruhr University Bochum
Wolfgang Hillen
Wolfgang Hillen University of Erlangen-Nuremberg
Giuseppe Legname
Giuseppe Legname International School for Advanced Studies

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