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Immunology

D-Index
84
Citations
31724
World Ranking
1346
National Ranking
693

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2016 - AAI-BioLegend Herzenberg Award, American Association of Immunologists

Overview

John F. Kearney is affiliated with the University of Alabama at Birmingham in the United States. The primary focus of their research is on immunology and microbiology, with additional work in biochemistry, genetics, molecular biology, and medicine.

The scientist's work covers several main topics, including:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Diabetes and associated disorders
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research

Kearney has published research in various scientific venues, with frequent contributions to:

  • The Journal of Immunology
  • Immunity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Preprints.org
  • Nature Communications

Notable recent papers include:

  • Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development, 2020, Immunity
  • Chloroquine as a Potential Treatment and Prevention Measure for the 2019 Novel Coronavirus: A Review, 2020, Preprints.org
  • Intrathymic differentiation of natural antibody-producing plasma cells in human neonates, 2021, Nature Communications
  • Concordance rate between copy number variants detected using either high- or medium-density single nucleotide polymorphism genotype panels and the potential of imputing copy number variants from flanking high density single nucleotide polymorphism haplotypes in cattle, 2020, BMC Genomics
  • B-1 B Cell-Derived Natural Antibodies against N-Acetyl-d-Glucosamine Suppress Autoimmune Diabetes Pathogenesis, 2023, The Journal of Immunology

Frequent co-authors of Kearney's work include:

  • R. Glenn King
  • James S. New
  • Alexander F. Rosenberg
  • Christopher Fucile
  • Brian Dizon

In recognition of contributions to their field, Kearney has received:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2018
  • AAI-BioLegend Herzenberg Award, American Association of Immunologists, 2016

Best Publications

  • AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells

    Amy H. Yin;Sheri Miraglia;Esmail D. Zanjani;Graca Almeida-Porada

  • A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines

    John F. Kearney;Andreas Radbruch;Bernhard Liesegang;Klaus Rajewsky

  • Marginal Zone and B1 B Cells Unite in the Early Response against T-Independent Blood-Borne Particulate Antigens

    Flavius Martin;Alyce M Oliver;John F Kearney

  • Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

    D G Bole;L M Hendershot;J F Kearney

  • Marginal-zone B cells.

    Flavius Martin;John F Kearney

  • Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines.

    George D. Yancopoulos;Stephen V. Desiderio;Michael Paskind;John F. Kearney

  • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.

    Mercedesz Balázs;Flavius Martin;Tong Zhou;John F Kearney

  • PI3 kinase signals BCR-dependent mature B cell survival.

    Lakshmi Srinivasan;Yoshiteru Sasaki;Dinis Pedro Calado;Baochun Zhang

  • Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

    Walter Schuler;Ivan Jeanne Weiler;Amelie Schuler;Robert A. Phillips

  • ANTIPHOSPHOCHOLINE ANTIBODIES FOUND IN NORMAL MOUSE SERUM ARE PROTECTIVE AGAINST INTRAVENOUS INFECTION WITH TYPE 3 STREPTOCOCCUS PNEUMONIAE

    David E. Briles;Moon Nahm;Kenneth Schroer;Joseph Davie

  • B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".

    Flavius Martin;John F. Kearney

  • Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses.

    A M Oliver;F Martin;G L Gartland;R H Carter

  • Autoreactivity by design: innate B and T lymphocytes.

    Albert Bendelac;Marc Bonneville;John F. Kearney

  • B1 cells: similarities and differences with other B cell subsets.

    Flavius Martin;John F Kearney

  • IgMhighCD21high Lymphocytes Enriched in the Splenic Marginal Zone Generate Effector Cells More Rapidly Than the Bulk of Follicular B Cells

    Alyce M. Oliver;Flavius Martin;John F. Kearney

  • Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein.

    L Hendershot;D Bole;G Köhler;J F Kearney

  • Developmentally Controlled Expression of Immunoglobulin VH Genes

    Roger M. Perlmutter;John F. Kearney;Sandra P. Chang;Leroy E. Hood

  • Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk.

    Flavius Martin;John F. Kearney

  • Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.

    Kalaya Attanavanich;John F. Kearney

  • Development and selection of marginal zone B cells

    Thiago Lopes-Carvalho;John F. Kearney

Frequent Co-Authors

Max D. Cooper
Max D. Cooper Emory University
Hiromi Kubagawa
Hiromi Kubagawa University of Alabama at Birmingham
David E. Briles
David E. Briles University of Alabama at Birmingham
Charles L. Turnbough
Charles L. Turnbough University of Alabama at Birmingham
John E. Volanakis
John E. Volanakis University of Alabama at Birmingham
Agnès Lehuen
Agnès Lehuen Université Paris Cité
Jerry R. McGhee
Jerry R. McGhee University of Alabama at Birmingham
Harry W. Schroeder
Harry W. Schroeder University of Alabama at Birmingham
William H. Benjamin
William H. Benjamin University of Alabama at Birmingham
Jan Klein
Jan Klein Pennsylvania State University

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