D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 66 Citations 22,883 146 World Ranking 3854 National Ranking 1947

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

His primary scientific interests are in Biochemistry, Rhodopsin, Cell biology, Recoverin and Molecular biology. His work carried out in the field of Biochemistry brings together such families of science as Biophysics and Calcium. His biological study spans a wide range of topics, including Membrane and GUCY2D.

James B. Hurley interconnects Myristoylation, Phosphorylation, Phosphodiesterase and Protein subunit in the investigation of issues within Rhodopsin. His Cell biology study combines topics in areas such as Arrestin beta 2, Retina, Outer nuclear layer, Phototaxis and Arrestin beta 1. His Recoverin study integrates concerns from other disciplines, such as Binding protein and Neurocalcin.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
  • Flow of information in the light-triggered cyclic nucleotide cascade of vision. (654 citations)
  • Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase. (504 citations)

What are the main themes of his work throughout his whole career to date?

James B. Hurley mainly investigates Cell biology, Biochemistry, Biophysics, Retinal and Retina. His Cell biology research includes elements of Glycolysis, Metabolism, Visual phototransduction and Zebrafish. His Biochemistry study frequently draws connections to other fields, such as Rhodopsin kinase.

The various areas that James B. Hurley examines in his Biophysics study include Membrane and Retinal Rod Photoreceptor Cells. His Retina study introduces a deeper knowledge of Neuroscience. As a part of the same scientific study, James B. Hurley usually deals with the Recoverin, concentrating on Calcium and frequently concerns with GUCY2D.

He most often published in these fields:

  • Cell biology (42.86%)
  • Biochemistry (34.76%)
  • Biophysics (18.57%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (42.86%)
  • Retinal (18.57%)
  • Retina (18.57%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, Retinal, Retina, Retinal pigment epithelium and Metabolism. His Cell biology study incorporates themes from Retinal degeneration, Visual phototransduction, Zebrafish and Glycolysis. Glycolysis is the subject of his research, which falls under Biochemistry.

James B. Hurley combines topics linked to Calcium with his work on Biochemistry. His research on Retinal also deals with topics like

  • Metabolomics, which have a strong connection to Disease, Degeneration, Purine and Choroid,
  • Macular degeneration, Retinal pathology, Neuroscience and Mitochondrial DNA most often made with reference to Proteomics. His Metabolism research focuses on Glutamine and how it connects with Internal medicine, Endocrinology and Ex vivo.

Between 2016 and 2021, his most popular works were:

  • Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye (122 citations)
  • Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side (45 citations)
  • Loss of MPC1 reprograms retinal metabolism to impair visual function. (32 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

The scientist’s investigation covers issues in Cell biology, Retina, Metabolism, Retinal and Mitochondrion. His Cell biology research is multidisciplinary, relying on both Photoreceptor outer segment, Photoreceptor protein, Glycolysis, Zebrafish and Visual phototransduction. James B. Hurley has researched Retina in several fields, including Metabolite, Electron transport chain, Succinate dehydrogenase and Cytochrome c oxidase.

His Metabolite study is concerned with the larger field of Biochemistry. Rod cell, Lipid metabolism, Phosphodiesterase and Kinase is closely connected to Retinal degeneration in his research, which is encompassed under the umbrella topic of Metabolism. His studies deal with areas such as Flux and Anatomy as well as Retinal.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

7068 Citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

Bernard K. K. Fung;James B. Hurley;Lubert Stryer.
Proceedings of the National Academy of Sciences of the United States of America (1981)

924 Citations

Distribution and morphology of human cone photoreceptors stained with anti-blue opsin.

Christine A. Curcio;Kimberly A. Allen;Kenneth R. Sloan;Connie L. Lerea.
The Journal of Comparative Neurology (1991)

651 Citations

Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase.

Alexander M. Dizhoor;Sanghamitra Ray;Santosh Kumar;Greg Niemi.
Science (1991)

628 Citations

A thyroid hormone receptor that is required for the development of green cone photoreceptors.

Lily Ng;James B. Hurley;Blair Dierks;Maya Srinivas.
Nature Genetics (2001)

534 Citations

The human photoreceptor membrane guanylyl cyclase, RetGC, is present in outer segments and is regulated by calcium and a soluble activator

Alexander M. Dizhoor;David G. Lowe;Elena V. Olshevskaya;Richard P. Laura.
Neuron (1994)

450 Citations

Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments.

J B Hurley;L Stryer.
Journal of Biological Chemistry (1982)

445 Citations

A behavioral screen for isolating zebrafish mutants with visual system defects

Susan E. Brockerhoff;James B. Hurley;Ulrike Janssen-Bienhold;Stephan C. F. Neuhauss.
Proceedings of the National Academy of Sciences of the United States of America (1995)

440 Citations

Cloning, Sequencing, and Expression of a 24-kDa Ca2+-binding Protein Activating Photoreceptor Guanylyl Cyclase

Alexander M. Dizhoor;Elena V. Olshevskaya;William J. Henzel;Susan C. Wong.
Journal of Biological Chemistry (1995)

419 Citations

Transduction mechanisms of vertebrate and invertebrate photoreceptors.

Stuart Yarfitz;James B. Hurley.
Journal of Biological Chemistry (1994)

400 Citations

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