World's Best Scientists 2026 revealed!
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Melvin I. Simon
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Molecular Biology
USA
2026

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Molecular Biology 137 144 128 92 81 344 55770

Melvin I. Simon publications per year

The chart shows the history of publications by Melvin I. Simon between 1964 and 2023, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Melvin I. Simon published across 60 years, from 1964 to 2023, averaging 6.7 papers a year. Output peaked at 24 publications in 1996. 1 of the 402 publications appeared in the last two years.

No. of publications
5 10 15 20
Bar chart. Horizontal axis: year, 1964 to 2023. Vertical axis: number of publications, 0 to 24. Peak 24 publications in 1996. 1964: 1 publication 1965: 1 publication 1966: 0 publications 1967: 1 publication 1968: 4 publications 1969: 3 publications 1970: 1 publication 1971: 6 publications 1972: 1 publication 1973: 3 publications 1974: 5 publications 1975: 0 publications 1976: 3 publications 1977: 10 publications 1978: 4 publications 1979: 2 publications 1980: 4 publications 1981: 4 publications 1982: 2 publications 1983: 10 publications 1984: 8 publications 1985: 11 publications 1986: 7 publications 1987: 9 publications 1988: 17 publications 1989: 9 publications 1990: 16 publications 1991: 16 publications 1992: 17 publications 1993: 18 publications 1994: 10 publications 1995: 22 publications 1996: 24 publications 1997: 22 publications 1998: 12 publications 1999: 9 publications 2000: 18 publications 2001: 13 publications 2002: 16 publications 2003: 14 publications 2004: 9 publications 2005: 5 publications 2006: 8 publications 2007: 6 publications 2008: 1 publication 2009: 3 publications 2010: 3 publications 2011: 6 publications 2012: 1 publication 2013: 4 publications 2014: 0 publications 2015: 0 publications 2016: 2 publications 2017: 0 publications 2018: 0 publications 2019: 0 publications 2020: 0 publications 2021: 0 publications 2022: 0 publications 2023: 1 publication
1964 2023

402 publications in total across all disciplines

View publications per year as a table
Melvin I. Simon: publications per year, 1964 to 2023
Year Publications
1964 1
1965 1
1966 0
1967 1
1968 4
1969 3
1970 1
1971 6
1972 1
1973 3
1974 5
1975 0
1976 3
1977 10
1978 4
1979 2
1980 4
1981 4
1982 2
1983 10
1984 8
1985 11
1986 7
1987 9
1988 17
1989 9
1990 16
1991 16
1992 17
1993 18
1994 10
1995 22
1996 24
1997 22
1998 12
1999 9
2000 18
2001 13
2002 16
2003 14
2004 9
2005 5
2006 8
2007 6
2008 1
2009 3
2010 3
2011 6
2012 1
2013 4
2014 0
2015 0
2016 2
2017 0
2018 0
2019 0
2020 0
2021 0
2022 0
2023 1
Total 402
Download as CSV

Melvin I. Simon publications per year - data summary

  • Melvin I. Simon, a Molecular Biology scholar from California Institute of Technology, has 402 publications recorded across 60 years, from 1964 to 2023.
  • The oldest publication on record dates to 1964 and the most recent to 2023.
  • The most productive year is 1996, with 24 publications.
  • The least productive years with any output are 1964, 1965, 1967, 1970 and others, with 1 publication each.
  • 10 of the 60 years in the span carry no publications at all (1966, 1975, 2014, 2015 and others).
  • The rate of publication averages 6.7 papers per year over the whole span, or 8.0 per year counting only the 50 years with at least one publication.
  • The last 5 years on the chart (2019-2023) hold 1 publication, <1% of the career total.
  • Split into equal eras - 1964-1983: 65 publications (3.3 per year); 1984-2003: 288 publications (14.4 per year); 2004-2023: 49 publications (2.5 per year).
  • Comparing the opening and closing eras, the overall trend of publication is broadly steady.

Melvin I. Simon publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Melvin I. Simon sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 53 bars. Horizontal axis: publications, 47–56 to 564+. Vertical axis: number of scientists, 0 to 177. Most scientists, 177, have 117–126 publications. The last bar groups every scientist with 564 publications or more. The highlighted bar, 337–346 publications, is where this scientist sits. 47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47–56 publications 564+

This scientist: 344 publications — 86th percentile

86% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

View publications distribution as a table
Number of Molecular Biology scientists by publication count, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
Publications Scientists This scientist
47–56 7
57–66 17
67–76 65
77–86 90
87–96 125
97–106 131
107–116 162
117–126 177
127–136 158
137–146 158
147–156 146
157–166 159
167–176 131
177–186 110
187–196 112
197–206 100
207–216 89
217–226 98
227–236 74
237–246 72
247–256 63
257–266 53
267–276 54
277–286 49
287–296 52
297–306 43
307–316 46
317–326 41
327–336 42
337–346 31 344
347–356 28
357–366 29
367–376 26
377–386 24
387–396 24
397–406 14
407–416 13
417–426 20
427–436 12
437–446 20
447–456 11
457–466 10
467–476 14
477–486 14
487–496 10
497–506 13
507–516 13
517–526 2
527–536 4
537–546 6
547–556 8
557–563 6
564+ 100
Download as CSV

Melvin I. Simon publication distribution in Molecular Biology in 2026 - data summary

  • The chart plots the publication count of all 3,076 Molecular Biology scientists ranked by Research.com in 2026, grouped into 53 ranges running from 47–56 to 564+ publications.
  • Melvin I. Simon, a Molecular Biology scholar from California Institute of Technology, records 344 publications - the 86th percentile of the discipline.
  • 86% of ranked Molecular Biology scientists score the same or lower than Melvin I. Simon, and about 14% score higher.
  • The median of the discipline falls in the 177–186 publications range, and Melvin I. Simon ranks above the median.
  • The most crowded range is 117–126 publications, holding 177 scientists (6% of the field).
  • 53% of the field sits in the lowest quarter of the value range (up to 177–186 publications), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 564 publications or more, 100 scientists in all (3% of the field).

Melvin I. Simon D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Melvin I. Simon sits on this spectrum.

No. of scientists
25 50 75 100 125
Bar chart with 54 bars. Horizontal axis: D-Index, 40–41 to 145+. Vertical axis: number of scientists, 0 to 131. Most scientists, 131, have 64–65 D-Index. The last bar groups every scientist with 145 D-Index or more. The highlighted bar, 136–137 D-Index, is where this scientist sits. 40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40–41 D-Index 145+

This scientist: 137 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

View D-Index distribution as a table
Number of Molecular Biology scientists by D-index, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
D-Index Scientists This scientist
40–41 36
42–43 101
44–45 115
46–47 121
48–49 118
50–51 130
52–53 106
54–55 116
56–57 113
58–59 129
60–61 120
62–63 105
64–65 131
66–67 95
68–69 97
70–71 106
72–73 83
74–75 89
76–77 77
78–79 70
80–81 73
82–83 60
84–85 48
86–87 45
88–89 50
90–91 31
92–93 51
94–95 43
96–97 38
98–99 39
100–101 41
102–103 29
104–105 33
106–107 35
108–109 20
110–111 38
112–113 19
114–115 28
116–117 13
118–119 23
120–121 16
122–123 15
124–125 11
126–127 21
128–129 7
130–131 13
132–133 14
134–135 17
136–137 9 137
138–139 8
140–141 16
142–143 7
144 7
145+ 100
Download as CSV

Melvin I. Simon D-index placement in Molecular Biology in 2026 - data summary

  • The chart plots the discipline H-index (D-index) of all 3,076 Molecular Biology scientists ranked by Research.com in 2026, grouped into 54 ranges running from 40–41 to 145+ D-Index.
  • Melvin I. Simon, a Molecular Biology scholar from California Institute of Technology, records 137 D-Index - the 96th percentile of the discipline.
  • 96% of ranked Molecular Biology scientists score the same or lower than Melvin I. Simon, and about 4% score higher.
  • The median of the discipline falls in the 68–69 D-Index range, and Melvin I. Simon ranks above the median.
  • The most crowded range is 64–65 D-Index, holding 131 scientists (4% of the field).
  • 50% of the field sits in the lowest quarter of the value range (up to 66–67 D-Index), so the distribution leans towards the lower end of the scale.
  • The final bar has no upper bound: it groups every scientist with 145 D-Index or more, 100 scientists in all (3% of the field).

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 1987 - Fellow of the American Academy of Arts and Sciences
  • 1985 - Member of the National Academy of Sciences
  • 1978 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Biochemistry, G protein, Heterotrimeric G protein, G alpha subunit and Phosphorylation. The G protein study combines topics in areas such as Molecular biology, Phospholipase C and Alpha. He works mostly in the field of Molecular biology, limiting it down to topics relating to Cholera toxin and, in certain cases, Amino acid.

Genetics and Cell biology are the focus of his Heterotrimeric G protein studies. His G alpha subunit study deals with Peptide sequence intersecting with Nucleic acid sequence. His biological study spans a wide range of topics, including Histidine kinase, Biophysics and Chemotaxis.

His most cited work include:

  • Diversity of G proteins in signal transduction. (1738 citations)
  • Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. (1532 citations)
  • The DNA sequence of human chromosome 22 (1150 citations)

What are the main themes of his work throughout his whole career to date?

Melvin I. Simon mostly deals with Biochemistry, G protein, Molecular biology, Cell biology and Genetics. His work focuses on many connections between Biochemistry and other disciplines, such as Biophysics, that overlap with his field of interest in Rhodopsin. His study connects G alpha subunit and G protein.

His study looks at the relationship between Molecular biology and fields such as Gene expression, as well as how they intersect with chemical problems. His Cell biology research focuses on Signal transduction in particular. His Phosphorylation research is multidisciplinary, incorporating perspectives in Histidine kinase, Mutant and Chemotaxis.

He most often published in these fields:

  • Biochemistry (33.59%)
  • G protein (27.73%)
  • Molecular biology (25.78%)

What were the highlights of his more recent work (between 2001-2016)?

  • Cell biology (25.00%)
  • Signal transduction (18.75%)
  • Biochemistry (33.59%)

In recent papers he was focusing on the following fields of study:

Melvin I. Simon mainly focuses on Cell biology, Signal transduction, Biochemistry, G protein and Receptor. His Cell biology research integrates issues from Retinal degeneration, Rhodopsin, Visual phototransduction and Ectopic expression. His work carried out in the field of Signal transduction brings together such families of science as Molecular biology and Computational biology.

Melvin I. Simon has included themes like Cell culture and G alpha subunit in his G protein study. Melvin I. Simon usually deals with Receptor and limits it to topics linked to Neuroscience and Transduction. His study on G beta-gamma complex is often connected to Physiological responses as part of broader study in Heterotrimeric G protein.

Between 2001 and 2016, his most popular works were:

  • A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression (273 citations)
  • RGS9 Modulates Dopamine Signaling in the Basal Ganglia (238 citations)
  • Evidence for two apoptotic pathways in light-induced retinal degeneration (211 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Cell biology, Biochemistry, Receptor, Visual phototransduction and Rhodopsin are his primary areas of study. His Cell biology course of study focuses on Transcription factor and p38 mitogen-activated protein kinases, Ectopic expression, MAPK/ERK pathway and Muscarinic acetylcholine receptor. His Biophysics research extends to the thematically linked field of Biochemistry.

His work on Gq alpha subunit, HEK 293 cells and Calcium signaling as part of general Receptor research is frequently linked to CpG site, thereby connecting diverse disciplines of science. His work deals with themes such as Knockout mouse and Transducin, which intersect with Visual phototransduction. His studies in Rhodopsin integrate themes in fields like Arrestin, Phosphodiesterase activity, Transient receptor potential channel and Mechanism of action.

Best Publications

  • Diversity of G proteins in signal transduction.

    Melvin I. Simon;Michael P. Strathmann;Narasimhan Gautam

  • Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

    Hiroaki Shizuya;Bruce Birren;Ung-Jin Kim;Valeria Mancino

  • The DNA sequence of human chromosome 22

    I. Dunham;N. Shimizu;B. A. Roe;S. Chissoe

  • A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons

    Xinzhong Dong;Sang kyou Han;Mark J. Zylka;Melvin I. Simon

  • Defective platelet activation in G alpha q deficient mice

    Stefan Offermanns;Christopher F. Toombs;Yi-Hui Hu;Melvin I. Simon

  • Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C

    Stefan Offermanns;Melvin I. Simon

  • Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis.

    J F Hess;K Oosawa;N Kaplan;M I Simon

  • Signal Transduction Pathways Involving Protein Phosphorylation in Prokaryotes

    Rorbert B. Bourret;Katherine A. Borkovich;Melvin I. Simon

  • Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C

    Arieh Katz;Dianqing Wu;Melvin I. Simon

  • Construction and characterization of a human bacterial artificial chromosome library

    Ung Jin Kim;Bruce W. Birren;Tatiana Slepak;Valeria Mancino

  • Structure of CheA, a Signal-Transducing Histidine Kinase

    Alexandrine M. Bilwes;Lisa A. Alex;Brian R. Crane;Melvin I. Simon

  • G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.

    Michael Strathmann;Melvin I. Simon

  • The genome of Nanoarchaeum equitans: Insights into early archaeal evolution and derived parasitism

    Elizabeth Waters;Michael J. Hohn;Ivan Ahel;David E. Graham

  • Homologies between signal transducing G proteins and ras gene products

    James B. Hurley;Melvin I. Simon;David B. Teplow;Janet D. Robishaw

  • Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα13 Deficiency

    Stefan Offermanns;Valeria Mancino;Jean-Paul Revel;Melvin I. Simon

  • Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1

    Ching Kang Chen;Marie E Burns;Wel He;Theodorø G. Wensel

  • A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

    Kum Joo Shin;Estelle A. Wall;Joelle R. Zavzavadjian;Leah A. Santat

  • Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells.

    Dianqing Wu;Chang Ho Lee;Sue Goo Rhee;Melvin I. Simon

  • Histidine phosphorylation and phosphoryl group transfer in bacterial chemotaxis.

    J. Fred Hess;Robert B. Bourret;Melvin I. Simon

  • Antibodies to the alpha q subfamily of guanine nucleotide-binding regulatory protein alpha subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones.

    Stephen Gutowski;Alan Smrcka;Lisa Nowak;Dianging Wu

Frequent Co-Authors

Stefan Offermanns
Stefan Offermanns Max Planck Society
Brian R. Crane
Brian R. Crane Cornell University
Iain D. C. Fraser
Iain D. C. Fraser National Institutes of Health
Henry A. Lester
Henry A. Lester California Institute of Technology
Julie R. Korenberg
Julie R. Korenberg University of Utah
Paul C. Sternweis
Paul C. Sternweis The University of Texas Southwestern Medical Center
Leroy Hood
Leroy Hood University of Washington
Xinzhong Dong
Xinzhong Dong Johns Hopkins University School of Medicine
Paul W. Sternberg
Paul W. Sternberg California Institute of Technology
Thomas J. Hudson
Thomas J. Hudson Ontario Institute for Cancer Research

External Links

Personal website of Melvin I. Simon

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Related Online Degrees & Career Pathways

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Best Scientists Citing Melvin I. Simon

Stefan Offermanns

Stefan Offermanns

Max Planck Society

Publications: 139

Vsevolod V. Gurevich

Vsevolod V. Gurevich

Vanderbilt University

Publications: 76

Heidi E. Hamm

Heidi E. Hamm

Vanderbilt University

Publications: 70

Xinzhong Dong

Xinzhong Dong

Johns Hopkins University School of Medicine

Publications: 67

Graeme Milligan

Graeme Milligan

University of Glasgow

Publications: 61

Yung Hou Wong

Yung Hou Wong

Hong Kong University of Science and Technology

Publications: 59

Kirill A. Martemyanov

Kirill A. Martemyanov

Scripps Research Institute

Publications: 59

Masahiko Watanabe

Masahiko Watanabe

Hokkaido University

Publications: 57

Krzysztof Palczewski

Krzysztof Palczewski

University of California, Irvine

Publications: 52

Lutz Birnbaumer

Lutz Birnbaumer

National Institutes of Health

Publications: 49

Alan G. Barbour

Alan G. Barbour

University of California, Irvine

Publications: 49

Jeffry B. Stock

Jeffry B. Stock

Princeton University

Publications: 48

Vadim Y. Arshavsky

Vadim Y. Arshavsky

Duke University

Publications: 47

Stanley B. Prusiner

Stanley B. Prusiner

University of California, San Francisco

Publications: 46

Ann M. Stock

Ann M. Stock

Rutgers, The State University of New Jersey

Publications: 46

Alfred G. Gilman

Alfred G. Gilman

The University of Texas Southwestern Medical Center

Publications: 45

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