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D-Index & Metrics

Chemistry

D-Index
69
Citations
15111
World Ranking
6290
National Ranking
1914

Research.com Recognitions

  • 2013 - Fellow of John Simon Guggenheim Memorial Foundation
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Fellow of Alfred P. Sloan Foundation

Overview

Brian R. Crane is affiliated with Cornell University in the United States and has an extensive body of work primarily situated within the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Plant Science, Cellular and Molecular Neuroscience, Parasitology, and Endocrine and Autonomic Systems.

Their research topics focus notably on Photosynthetic Processes and Mechanisms, Photoreceptor and Optogenetics Research, Light Effects on Plants, Circadian Rhythm and Melatonin, Vector-borne Infectious Diseases, Bacterial Genetics and Biotechnology, and Electron Spin Resonance Studies.

Brian R. Crane's recent papers demonstrate a concentration on molecular mechanisms related to light perception and circadian rhythms. These include:

  • Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome (2021, Communications Biology)
  • Cryptochrome-Timeless structure reveals circadian clock timing mechanisms (2023, Nature)
  • Atypical chemoreceptor arrays accommodate high membrane curvature (2020, Nature Communications)
  • Mechanistic insight into light-dependent recognition of Timeless by Drosophila Cryptochrome (2022, Structure)
  • Redox properties and PAS domain structure of the Escherichia coli energy sensor Aer indicate a multistate sensing mechanism (2022, Journal of Biological Chemistry)

Their frequent coauthors include Siddarth Chandrasekaran, Chunhao Li, Michael J. Lynch, Changfan Lin, and Kurni Kurniyati, reflecting ongoing collaborative efforts in related biochemical and molecular biological investigations.

The most common venues for Brian R. Crane's publications are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Biological Chemistry
  • Biochemistry
  • eLife

Brian R. Crane has received several distinctions such as being named a Fellow of the John Simon Guggenheim Memorial Foundation in 2013, a Fellow of the American Association for the Advancement of Science (AAAS) in 2011, and a Fellow of the Alfred P. Sloan Foundation in 2005.

Best Publications

  • Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.

    Brian R. Crane;Brian R. Crane;Andrew S. Arvai;Dipak K. Ghosh;Chaoqun Wu

  • Structure of CheA, a Signal-Transducing Histidine Kinase

    Alexandrine M. Bilwes;Lisa A. Alex;Brian R. Crane;Melvin I. Simon

  • Tryptophan-Accelerated Electron Flow Through Proteins

    Crystal Shih;Anna Katrine Museth;Malin Abrahamsson;Ana Maria Blanco-Rodriguez

  • The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.

    Brian R. Crane;Andrew S. Arvai;Ratan Gachhui;Chaoqun Wu

  • Conformational switching in the fungal light sensor Vivid.

    Brian D. Zoltowski;Carsten Schwerdtfeger;Carsten Schwerdtfeger;Joanne Widom;Joanne Widom;Jennifer J. Loros;Jennifer J. Loros

  • Sulfite Reductase Structure at 1.6 Å: Evolution and Catalysis for Reduction of Inorganic Anions

    Brian R. Crane;Lewis M. Siegel;Elizabeth D. Getzoff

  • AtNOS/AtNOA1 Is a Functional Arabidopsis thaliana cGTPase and Not a Nitric-oxide Synthase *

    Magali Moreau;Gyu In Lee;Yongzeng Wang;Brian R. Crane

  • Mechanism-based tuning of a LOV domain photoreceptor

    Brian D Zoltowski;Brian Vaccaro;Brian R Crane

  • Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins.

    Ariane Briegel;Xiaoxiao Li;Alexandrine M. Bilwes;Kelly T. Hughes

  • Photochemistry of flavoprotein light sensors.

    Karen S Conrad;Craig C Manahan;Brian R Crane

  • Reconstruction of the Chemotaxis Receptor-Kinase Assembly

    Sang-Youn Park;Peter P Borbat;Gabriela Gonzalez-Bonet;Jaya Bhatnagar

  • Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.

    Elsa D. Garcin;Elsa D. Garcin;Andrew S. Arvai;Robin J. Rosenfeld;Matt D. Kroeger;Matt D. Kroeger

  • Nitration of a peptide phytotoxin by bacterial nitric oxide synthase

    Johan A. Kers;Michael J. Wach;Stuart B. Krasnoff;Joanne Widom

  • Bacterial nitric oxide synthases.

    Brian R Crane;Jawahar Sudhamsu;Bhumit A Patel

  • Cytochrome P450–catalyzed L -tryptophan nitration in thaxtomin phytotoxin biosynthesis

    Sarah M Barry;Johan A Kers;Johan A Kers;Evan G Johnson;Evan G Johnson;Lijiang Song

  • Light activation of the LOV protein Vivid generates a rapidly exchanging dimer

    Brian D. Zoltowski;Brian R. Crane

  • Tetrahydrobiopterin radical enzymology.

    Chin Chuan Wei;Brian R. Crane;Dennis J. Stuehr

  • Nucleotide binding by the histidine kinase CheA

    Alexandrine M. Bilwes;Cindy M. Quezada;Laura R. Croal;Brian R. Crane;Brian R. Crane

  • Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.

    Brian R. Crane;Angel J. Di Bilio;Jay R. Winkler;Harry B. Gray

  • Structure of full-length Drosophila cryptochrome

    Brian D. Zoltowski;Anand T. Vaidya;Deniz Top;Joanne Widom

  • The relationship between structure and function for the sulfite reductases

    Brian R Crane;Elizabeth D Getzoff

Frequent Co-Authors

Elizabeth D. Getzoff
Elizabeth D. Getzoff Scripps Research Institute
Jack H. Freed
Jack H. Freed Cornell University
Jay R. Winkler
Jay R. Winkler California Institute of Technology
Dennis J. Stuehr
Dennis J. Stuehr Cleveland Clinic Lerner College of Medicine
Harry B. Gray
Harry B. Gray California Institute of Technology
Melvin I. Simon
Melvin I. Simon California Institute of Technology
John A. Tainer
John A. Tainer The University of Texas MD Anderson Cancer Center
Andrew S. Arvai
Andrew S. Arvai Scripps Research Institute
Antonín Vlček
Antonín Vlček Czech Academy of Sciences
Michael W. Young
Michael W. Young Rockefeller University

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