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Microbiology

D-Index
59
Citations
10041
World Ranking
3329
National Ranking
1314

Overview

Alexander J. Szalai is affiliated with the University of Alabama at Birmingham in the United States. Their research focuses primarily on medicine, with specific work in immunology and microbiology. The subfields they contribute to include immunology, epidemiology, surgery, infectious diseases, and nephrology.

The scientist's recent publications cover a range of topics in immunology and clinical research. Notable papers include:

  • Therapeutic Lowering of C-Reactive Protein, 2021, Frontiers in Immunology
  • Clustering Patients With Gout Based on Comorbidities and Biomarkers: A Cross-Sectional Study, 2022, The Journal of Rheumatology
  • Decreased Levels of STAT1 and Interferon-γ-Induced STAT1 Phosphorylation in Rheumatoid Arthritis CD4 and CD8 T Cells, 2021, ACR Open Rheumatology
  • Immortalized Human Conjunctival Epithelial Cells Produce Functional Complement C3 and C4 Proteins, 2023, Cornea

The main topics of their research include adipokines, inflammation, and metabolic diseases; lipoproteins and cardiovascular health; COVID-19 clinical research studies; gout, hyperuricemia, and uric acid; inflammasome and immune disorders; liver disease diagnosis and treatment; and T-cell and B-cell immunology.

Frequent co-authors collaborating with Szalai are:

  • Rachel V. Jimenez
  • Fatima K. Alduraibi
  • Mohammad Saleem
  • Karina Ricart
  • Rakesh P. Patel

Their work has been published in the following venues:

  • Frontiers in Immunology
  • The Journal of Rheumatology
  • ACR Open Rheumatology
  • Cornea

Best Publications

  • Induction of leptin resistance through direct interaction of C-reactive protein with leptin.

    Ke Chen;Fanghong Li;Ji Li;Hongbo Cai

  • Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice.

    Haim D. Danenberg;Alexander J. Szalai;Rajesh V. Swaminathan;Lin Peng

  • Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae

    Anh-Hue T. Tu;Robert L. Fulgham;Mark A. McCrory;David E. Briles

  • C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk.

    Fadi G. Hage;Alexander J. Szalai

  • HUMAN C-REACTIVE PROTEIN IS PROTECTIVE AGAINST FATAL STREPTOCOCCUS PNEUMONIAE INFECTION IN TRANSGENIC MICE

    A J Szalai;D E Briles;J E Volanakis

  • C-reactive Protein: A Physiological Activator of Interleukin 6 Receptor Shedding

    Simon A. Jones;Daniela Novick;Sankichi Horiuchi;Naoki Yamamoto

  • Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level

    A. J. Szalai;A. J. Szalai;J. Wu;E. M. Lange;M. A. McCrory

  • Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro

    Robert Kleemann;Lars Verschuren;Bert-Jan de Rooij;Jan Lindeman

  • Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface.

    Bing Ren;Alexander J. Szalai;Susan K. Hollingshead;David E. Briles

  • Association between baseline levels of C-reactive protein (CRP) and a dinucleotide repeat polymorphism in the intron of the CRP gene

    Alex J. Szalai;M. A. McCrory;G. S. Cooper;Jianming Wu

  • FcγRs Modulate Cytotoxicity of Anti-Fas Antibodies: Implications for Agonistic Antibody-Based Therapeutics

    Yuanyuan Xu;Alexander J. Szalai;Tong Zhou;Kurt R. Zinn

  • Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA.

    Antonella Circolo;Gérard Garnier;Gérard Garnier;Wataru Fukuda;Wataru Fukuda;Xeufeng Wang;Xeufeng Wang

  • Both Family 1 and Family 2 PspA Proteins Can Inhibit Complement Deposition and Confer Virulence to a Capsular Serotype 3 Strain of Streptococcus pneumoniae

    Bing Ren;Alexander J. Szalai;Orlanda Thomas;Susan K. Hollingshead

  • Testosterone and IL-6 Requirements for Human C-Reactive Protein Gene Expression in Transgenic Mice

    A J Szalai;F W van Ginkel;S A Dalrymple;R Murray

  • C-reactive protein: structural biology and host defense function.

    Alexander J. Szalai;Alok Agrawal;Trevor J. Greenhough;John E. Volanakis

  • Human c-reactive protein is protective against fatal Salmonella enterica serovar Typhimurium infection in transgenic mice

    Alexander J. Szalai;J. L. VanCott;Jerry R. McGhee;John E. Volanakis

  • The virulence function of Streptococcus pneumoniae surface protein a involves inhibition of complement activation and impairment of complement receptor-mediated protection

    Bing Ren;Mark A. McCrory;Christina Pass;Daniel C. Bullard

  • C-Reactive Protein Promotes Cardiac Fibrosis and Inflammation in Angiotensin II–Induced Hypertensive Cardiac Disease

    Rongxin Zhang;Yuan Yuan Zhang;Xiao R. Huang;Yin Wu

  • Attenuation of experimental autoimmune demyelination in complement-deficient mice.

    Serge Nataf;Steven L. Carroll;Rick A. Wetsel;Alexander J. Szalai

  • C-reactive protein: structural biology, gene expression, and host defense function.

    Alex J. Szalai;Alok Agrawal;Trevor J. Greenhough;John E. Volanakis

  • No Effect of C-Reactive Protein on Early Atherosclerosis Development in Apolipoprotein E*3-Leiden/Human C-Reactive Protein Transgenic Mice

    A. Trion;M.P.M. de Maat;J.W. Jukema;A. van der Laarse

Frequent Co-Authors

Scott R. Barnum
Scott R. Barnum CNine Biosolutions
David E. Briles
David E. Briles University of Alabama at Birmingham
John E. Volanakis
John E. Volanakis University of Alabama at Birmingham
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham
Suzanne Oparil
Suzanne Oparil University of Alabama at Birmingham
Jeffrey C. Edberg
Jeffrey C. Edberg University of Alabama at Birmingham
Hans M.G. Princen
Hans M.G. Princen Netherlands Organisation for Applied Scientific Research
Hui Y. Lan
Hui Y. Lan Chinese University of Hong Kong
Susan K. Hollingshead
Susan K. Hollingshead University of Alabama at Birmingham
Jerry R. McGhee
Jerry R. McGhee University of Alabama at Birmingham

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