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Overview

Sandra M. Swain is affiliated with Georgetown University Medical Center in the United States and has made significant contributions in the field of medical research, particularly in oncology. Their research focuses extensively on breast cancer, with a strong emphasis on HER2-positive breast cancer and advanced breast cancer therapies.

Their work spans a broad range of topics within medicine and biochemistry, genetics, and molecular biology, with a concentration on oncology and cancer research. Subfields of study include pulmonary and respiratory medicine, genetics, and radiology, nuclear medicine, and imaging. Key thematic areas addressed in their publications include:

  • HER2/EGFR in Cancer Research
  • Breast Cancer Treatment Studies
  • Advanced Breast Cancer Therapies
  • Cancer Treatment and Pharmacology
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers

Their research is frequently published in prominent venues such as:

  • Journal of Clinical Oncology
  • Cancer Research
  • Breast Cancer Research and Treatment
  • Cancers
  • Annals of Oncology

Notable recent papers authored by Sandra M. Swain include:

  • Targeting HER2-positive breast cancer: advances and future directions, 2022, Nature Reviews Drug Discovery
  • Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study, 2020, The Lancet Oncology
  • Multidisciplinary clinical guidance on trastuzumab deruxtecan (T-DXd)-related interstitial lung disease/pneumonitis-Focus on proactive monitoring, diagnosis, and management, 2022, Cancer Treatment Reviews

Frequent collaborators in their research include:

  • Charles E. Geyer
  • Priya Rastogi
  • Norman Wolmark
  • Eleftherios P. Mamounas
  • Paula R. Pohlmann

Best Publications

  • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

    Edward H. Romond;Edith A. Perez;John Bryant;Vera J. Suman

  • Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis

    Patricia Cortazar;Lijun Zhang;Michael Untch;Keyur Mehta

  • Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer

    José Baselga;Javier Cortés;Sung-Bae Kim;Seock-Ah Im

  • Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials.

    Sandra M. Swain;Fredrick S. Whaley;Michael S. Ewer

  • Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer

    Sandra M. Swain;José Baselga;Sung-Bae Kim;Jungsil Ro

  • Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials.

    R Peto;C Davies;J Godwin

  • 3rd ESO-ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 3)

    F. Cardoso;A. Costa;E. Senkus;M. Aapro

  • Novel anticancer targets: revisiting ERBB2 and discovering ERBB3

    José Baselga;Sandra M. Swain

  • Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study

    Sandra M Swain;Sung-Bae Kim;Javier Cortés;Jungsil Ro

  • Assessment of Cardiac Dysfunction in a Randomized Trial Comparing Doxorubicin and Cyclophosphamide Followed by Paclitaxel, With or Without Trastuzumab As Adjuvant Therapy in Node-Positive, Human Epidermal Growth Factor Receptor 2-Overexpressing Breast Cancer: NSABP B-31

    Elizabeth Tan-Chiu;Greg Yothers;Edward Romond;Charles E. Geyer

  • Trastuzumab Plus Adjuvant Chemotherapy for Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: Planned Joint Analysis of Overall Survival From NSABP B-31 and NCCTG N9831

    Edith A. Perez;Edward H. Romond;Vera J. Suman;Jong Hyeon Jeong

  • Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials

    Bernard Asselain;William Barlow;John Bartlett;Jonas Bergh

  • Long-Term Outcomes of Invasive Ipsilateral Breast Tumor Recurrences After Lumpectomy in NSABP B-17 and B-24 Randomized Clinical Trials for DCIS

    Irene L. Wapnir;James J. Dignam;Bernard Fisher;Eleftherios P. Mamounas

  • Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials

    J. Bergh;K. Pritchard;K. Albain;S. Anderson

  • Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer.

    Sandra M. Swain;Fredrick S. Whaley;Miriam C. Gerber;Steven Weisberg

  • Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

    Kip A. West;John Brognard;Amy S. Clark;Ilona R. Linnoila

  • Estimating the Risks of Breast Cancer Radiotherapy: Evidence From Modern Radiation Doses to the Lungs and Heart and From Previous Randomized Trials.

    Carolyn Taylor;Candace Correa;Frances K Duane;Marianne C Aznar

  • Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study

    Sandra M Swain;Sandra M Swain;David Miles;Sung-Bae Kim;Young-Hyuck Im

  • Bevacizumab added to neoadjuvant chemotherapy for breast cancer

    Harry D. Bear;Gong Tang;Priya Rastogi;Charles E. Geyer

  • Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer

    Suparna Bonthala Wedam;Jennifer A. Low;Sherry X. Yang;Catherine K. Chow

Frequent Co-Authors

Eleftherios P. Mamounas
Eleftherios P. Mamounas University of Florida Health
Norman Wolmark
Norman Wolmark University of Pittsburgh
Louis Fehrenbacher
Louis Fehrenbacher Kaiser Permanente
Joseph P. Costantino
Joseph P. Costantino University of Pittsburgh
Seth M. Steinberg
Seth M. Steinberg National Institutes of Health
Soonmyung Paik
Soonmyung Paik Yonsei University
Adam Brufsky
Adam Brufsky University of Pittsburgh
Charles E. Geyer
Charles E. Geyer University of Pittsburgh
José Baselga
José Baselga Memorial Sloan Kettering Cancer Center
Javier Cortes
Javier Cortes Vall d'Hebron Hospital Universitari

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