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Barbara Bottazzi

Barbara Bottazzi

D-Index & Metrics

Immunology

D-Index
87
Citations
24906
World Ranking
1219
National Ranking
46

Overview

Barbara Bottazzi is affiliated with Humanitas University in Italy and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans various subfields, including Immunology, Surgery, Infectious Diseases, Neurology, and Molecular Biology.

Their work focuses on several main research topics:

  • Biomarkers in Disease Mechanisms
  • Orthopedic Infections and Treatments
  • COVID-19 Clinical Research Studies
  • Orthopaedic implants and arthroplasty
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • Long-Term Effects of COVID-19

Barbara Bottazzi has published scientific papers in various reputable venues, with frequent publications in:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Leukemia

Recent papers by Barbara Bottazzi include:

  • Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules, 2022, Nature Immunology
  • Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19, 2020, Nature Immunology
  • Interleukin-15 and cancer: some solved and many unsolved questions, 2020, Journal for ImmunoTherapy of Cancer
  • Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course, 2023, Nature Immunology
  • Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus, 2021, Nature Communications

Barbara Bottazzi has collaborated frequently with several co-authors, including:

  • Alberto Mantovani
  • Roberto Leone
  • Cecília Garlanda
  • Marina Sironi
  • Antonio Inforzato

Best Publications

  • The origin and function of tumor-associated macrophages

    Alberto Mantovani;Barbara Bottazzi;Francesco Colotta;Silvano Sozzani

  • Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

    Cecilia Garlanda;Barbara Bottazzi;Antonio Bastone;Alberto Mantovani

  • A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)

    Subhra K. Biswas;Lisa Gangi;Saki Paul;Tiziana Schioppa

  • Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

    Cecilia Garlanda;Emilio Hirsch;Silvia Bozza;Antonietta Salustri

  • An integrated view of humoral innate immunity: pentraxins as a paradigm.

    Barbara Bottazzi;Andrea Doni;Cecilia Garlanda;Alberto Mantovani

  • p50 Nuclear Factor-κB Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

    Alessandra Saccani;Tiziana Schioppa;Chiara Porta;Subhra K. Biswas

  • Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component.

    F Breviario;E M d'Aniello;J Golay;G Peri

  • Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3.

    Alberto Mantovani;Cecilia Garlanda;Andrea Doni;Barbara Bottazzi

  • PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.

    Antonietta Salustri;Cecilia Garlanda;Emilio Hirsch;Marika De Acetis

  • Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF-κB Activation in Tumor-Associated Macrophages

    Antonio Sica;Alessandra Saccani;Barbara Bottazzi;Nadia Polentarutti

  • Multimer Formation and Ligand Recognition by the Long Pentraxin PTX3 SIMILARITIES AND DIFFERENCES WITH THE SHORT PENTRAXINS C-REACTIVE PROTEIN AND SERUM AMYLOID P COMPONENT

    Barbara Bottazzi;Valérie Vouret-Craviari;Antonio Bastone;Luca De Gioia

  • Regulation of leukocyte recruitment by the long pentraxin PTX3

    Livija Deban;Remo Castro Russo;Marina Sironi;Federica Moalli

  • Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.

    Alma J. Nauta;Barbara Bottazzi;Alberto Mantovani;Alberto Mantovani;Giovanni Salvatori

  • Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients.

    Beat Muller;Giuseppe Peri;Andrea Doni;Valter Torri

  • The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.

    Patrizia Rovere;Patrizia Rovere;Patrizia Rovere;Giuseppe Peri;Giuseppe Peri;Giuseppe Peri;Fausto Fazzini;Fausto Fazzini;Fausto Fazzini;Barbara Bottazzi;Barbara Bottazzi;Barbara Bottazzi

  • Production of the Long Pentraxin PTX3 in Advanced Atherosclerotic Plaques

    Michael S. Rolph;Sabine Zimmer;Barbara Bottazzi;Cecilia Garlanda

  • Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.

    Pascale Jeannin;Barbara Bottazzi;Marina Sironi;Andrea Doni

  • Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes

    Victor Vidai Alles;Barbara Bottazzi;Giuseppe Peri;Josée Golay

  • Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

    Livija Deban;Hanna Jarva;Hanna Jarva;Markus J. Lehtinen;Barbara Bottazzi

  • Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma.

    B Bottazzi;S Walter;D Govoni;F Colotta

  • Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

    Unknown

Frequent Co-Authors

Alberto Mantovani
Alberto Mantovani Humanitas University
Cecilia Garlanda
Cecilia Garlanda Humanitas University
Andrea Doni
Andrea Doni Humanitas Research Hospital
Marina Sironi
Marina Sironi Humanitas University
Giuseppe Peri
Giuseppe Peri Mario Negri Institute for Pharmacological Research
Nadia Polentarutti
Nadia Polentarutti Humanitas University
Roberto Latini
Roberto Latini Mario Negri Institute for Pharmacological Research
Giuseppe Danilo Norata
Giuseppe Danilo Norata University of Milan
Francesco Colotta
Francesco Colotta Mario Negri Institute for Pharmacological Research
Marco Presta
Marco Presta University of Brescia

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