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Microbiology

D-Index
64
Citations
17516
World Ranking
2588
National Ranking
62

Overview

Andrea Doni is affiliated with the Humanitas Research Hospital in Italy and has an extensive body of work in the biomedical research domain. Their research spans multiple interconnected fields such as immunology, microbiology, medicine, and molecular biology. Doni's contributions engage deeply with the study of immune responses, disease biomarkers, and molecular mechanisms involved in pathology.

Central topics in Doni's work include:

  • Biomarkers in Disease Mechanisms
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Single-cell and spatial transcriptomics
  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research

Doni's research outputs have been published extensively in venues such as Zenodo (CERN European Organization for Nuclear Research), Frontiers in Immunology, Nature Immunology, Cancer Research, and Scientific Reports. These platforms underline an emphasis on immunological and oncological topics alongside molecular biology.

Key publications by Andrea Doni include:

  • "Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules," 2022, Nature Immunology
  • "Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs," 2020, Cancer Research
  • "Heme catabolism by tumor-associated macrophages controls metastasis formation," 2021, Nature Immunology
  • "Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus," 2021, Nature Communications
  • "Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression," 2021, Nature Cancer

Doni has collaborated frequently with researchers including Alberto Mantovani, Cecília Garlanda, Marco Erreni, Barbara Bottazzi, and Raffaella Parente, indicating active engagement in collaborative immunology and oncology research networks.

The scientist's work covers several subfields, most notably:

  • Immunology
  • Molecular Biology
  • Oncology
  • Biophysics
  • Radiology, Nuclear Medicine and Imaging

The multidisciplinary nature of Doni's research integrates advanced methodologies such as single-cell transcriptomics and addresses the regulation of immune cell functions. This research contributes to broader understanding in cancer biology, host-pathogen interactions, and immune-mediated disease processes.

Best Publications

  • Regulation of the chemokine receptor CXCR4 by hypoxia.

    Tiziana Schioppa;Badarch Uranchimeg;Alessandra Saccani;Subhra K. Biswas

  • A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)

    Subhra K. Biswas;Lisa Gangi;Saki Paul;Tiziana Schioppa

  • Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

    Cecilia Garlanda;Emilio Hirsch;Silvia Bozza;Antonietta Salustri

  • An integrated view of humoral innate immunity: pentraxins as a paradigm.

    Barbara Bottazzi;Andrea Doni;Cecilia Garlanda;Alberto Mantovani

  • The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

    Sébastien Jaillon;Giuseppe Peri;Yves Delneste;Isabelle Frémaux

  • Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3.

    Alberto Mantovani;Cecilia Garlanda;Andrea Doni;Barbara Bottazzi

  • PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.

    Antonietta Salustri;Cecilia Garlanda;Emilio Hirsch;Marika De Acetis

  • Regulation of leukocyte recruitment by the long pentraxin PTX3

    Livija Deban;Remo Castro Russo;Marina Sironi;Federica Moalli

  • Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immunosuppressive Program

    Marcello Chieppa;Giancarlo Bianchi;Andrea Doni;Annalisa Del Prete

  • Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients.

    Beat Muller;Giuseppe Peri;Andrea Doni;Valter Torri

  • PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer

    Eduardo Bonavita;Stefania Gentile;Marcello Rubino;Virginia Maina

  • The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.

    Patrizia Rovere;Patrizia Rovere;Patrizia Rovere;Giuseppe Peri;Giuseppe Peri;Giuseppe Peri;Fausto Fazzini;Fausto Fazzini;Fausto Fazzini;Barbara Bottazzi;Barbara Bottazzi;Barbara Bottazzi

  • Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.

    Oscar M. Pello;Maria De Pizzol;Massimiliano Mirolo;Laura Soucek

  • Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers

    Giuseppe Di Caro;Francesca Bergomas;Fabio Grizzi;Andrea Doni

  • A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells

    Samantha Solito;Erika Falisi;Claudia Marcela Diaz-Montero;Andrea Doni

  • Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys.

    G D'Amico;G Frascaroli;G Bianchi;P Transidico

  • Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.

    Pascale Jeannin;Barbara Bottazzi;Marina Sironi;Andrea Doni

  • PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation.

    Fausto Fazzini;Giuseppe Peri;Andrea Doni;Giacomo Dell'Antonio

  • Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease.

    Stefania Vetrano;Maria Rescigno;Maria Rosaria Cera;Carmen Correale

  • CCR7 is involved in the migration of neutrophils to lymph nodes

    Céline Beauvillain;Céline Beauvillain;Pierre Cunin;Pierre Cunin;Andrea Doni;Mari Scotet;Mari Scotet

Frequent Co-Authors

Alberto Mantovani
Alberto Mantovani Humanitas University
Cecilia Garlanda
Cecilia Garlanda Humanitas University
Barbara Bottazzi
Barbara Bottazzi Humanitas University
Giuseppe Peri
Giuseppe Peri Mario Negri Institute for Pharmacological Research
Marina Sironi
Marina Sironi Humanitas University
Massimo Locati
Massimo Locati University of Milan
Luigina Romani
Luigina Romani University of Perugia
Peter Garred
Peter Garred University of Copenhagen
Yves Delneste
Yves Delneste University of Nantes
Paola Allavena
Paola Allavena Humanitas University

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