His primary areas of study are Molecular biology, Cytokine, Immunology, Cell biology and Inflammation. Francesco Colotta has included themes like Monocyte, Cell adhesion molecule, Cytotoxicity, Cytotoxic T cell and Mesothelial Cell in his Molecular biology study. His work deals with themes such as Tumor necrosis factor alpha, Receptor, Umbilical vein and Cancer cell, which intersect with Cytokine.
His studies examine the connections between Immunology and genetics, as well as such issues in Chemotaxis, with regards to Macrophage, Immunotherapy, Cell growth, Cancer research and Growth factor. His Cell biology research incorporates themes from Cancer therapy, Cell adhesion, Small molecule and Interleukin 1 receptor, type II. His research integrates issues of Endothelial stem cell, Tumor microenvironment, Cancer, Acquired immune system and Angiogenesis in his study of Inflammation.
His primary scientific interests are in Molecular biology, Immunology, Pharmacology, Cytokine and Chemotaxis. His Molecular biology research incorporates elements of Tumor necrosis factor alpha, Endothelial stem cell, Gene expression, Monocyte and Interleukin. His study in Immunology is interdisciplinary in nature, drawing from both Macrophage and Cytotoxicity.
His work carried out in the field of Cytokine brings together such families of science as Inflammation, Receptor and Mononuclear phagocyte system. Francesco Colotta has researched Chemotaxis in several fields, including Fibrosis, Aryl, Rheumatoid arthritis and Interleukin 8. In his study, which falls under the umbrella issue of Endocrinology, Interleukin 1 receptor, type II is strongly linked to Cell biology.
Francesco Colotta focuses on Pharmacology, Immunology, Aryl, Cancer research and Chemotaxis. His Pharmacology research is multidisciplinary, incorporating perspectives in Psoriasis, Interleukin 8, Rheumatoid arthritis, Ischemia and Fibrosis. In general Immunology study, his work on CXC chemokine receptors, Inflammation and Cytokine often relates to the realm of Ulcerative colitis, thereby connecting several areas of interest.
His Inflammation study combines topics from a wide range of disciplines, such as Acquired immune system, Immune system, Receptor and Infiltration. The Cytokine study combines topics in areas such as Hematopoietic growth factor and Lymphokine. He interconnects Tumor necrosis factor alpha, Ligand, Apoptosis and Kinase, Kinase activity in the investigation of issues within Cancer research.
Francesco Colotta mostly deals with Immunology, Biochemistry, Inflammation, Pharmacology and CXC chemokine receptors. His Immunology research is multidisciplinary, incorporating elements of Internal medicine, Renal function, Nephrology and Urology. His research is interdisciplinary, bridging the disciplines of Cell biology and Biochemistry.
His Inflammation research includes themes of Acquired immune system, Immune system, Infiltration, Cytokine and Receptor. The concepts of his Cytokine study are interwoven with issues in Cancer, Angiogenesis and Vascular permeability. His Pharmacology research also works with subjects such as
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Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability.
Francesco Colotta;Paola Allavena;Antonio Sica;Cecilia Garlanda.
Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products
Francesco Colotta;Fabio Re;Nadia Polentarutti;Silvano Sozzani.
The origin and function of tumor-associated macrophages
Alberto Mantovani;Barbara Bottazzi;Francesco Colotta;Silvano Sozzani.
Immunology Today (1992)
Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4
Francesco Colotta;Fabio Re;Marta Muzio;Riccardo Bertini.
Interleukin 1 signaling occurs exclusively via the type I receptor.
J E Sims;M A Gayle;J L Slack;M R Alderson.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells.
Fabio Re;Adriana Zanetti;Marina Sironi;Nadia Polentarutti.
Journal of Cell Biology (1994)
Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines
F Colotta;N Polentarutti;M Sironi;A Mantovani.
Journal of Biological Chemistry (1992)
The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1.
Francesco Colotta;Steven K. Dower;John E. Sims;Alberto Mantovani;Alberto Mantovani.
Immunology Today (1994)
Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor.
Antonio Sica;Ji Ming Wang;Francesco Colotta;Elisabetta Dejana.
Journal of Immunology (1990)
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: Prevention of reperfusion injury
Riccardo Bertini;Marcello Allegretti;Cinzia Bizzarri;Alessio Moriconi.
Proceedings of the National Academy of Sciences of the United States of America (2004)
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