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Immunology

D-Index
58
Citations
15416
World Ranking
3484
National Ranking
1618

Overview

Clifford M. Snapper is affiliated with the Uniformed Services University of the Health Sciences in the United States. Their research primarily focuses on medicine, with particular contributions in epidemiology, oncology, pathology and forensic medicine, and parasitology. The scientist has explored diverse aspects of viral-associated diseases, including herpetic infections and lymphoma diagnosis and treatment.

The main topics covered in their body of work include:

  • Viral-associated cancers and disorders
  • Herpesvirus infections and treatments
  • Cytomegalovirus and herpesvirus research
  • Lymphoma diagnosis and treatment
  • Polyomavirus and related diseases
  • Toxoplasma gondii research studies

Snapper has published multiple articles in scientific journals with a strong focus on viral immunology and vaccine development. Frequent publication venues include Vaccines and Frontiers in Immunology.

Recent notable publications include:

  • Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases, 2021, Frontiers in Immunology
  • Immunization with Epstein-Barr Virus Core Fusion Machinery Envelope Proteins Elicit High Titers of Neutralizing Activities and Protect Humanized Mice from Lethal Dose EBV Challenge, 2021, Vaccines
  • Immunization with Human Cytomegalovirus Core Fusion Machinery and Accessory Envelope Proteins Elicit Strong Synergistic Neutralizing Activities, 2020, Vaccines

The scientist collaborates with various coauthors in their research endeavors. Frequent collaborators include Xinle Cui, Zhouhong Cao, Yuriko Ishikawa, Sara Cui, and Ken-Ichi Imadome. Collaborations with such researchers have contributed to investigations on viral immunization and neutralizing antibody responses.

Best Publications

  • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production

    Clifford M. Snapper;William E. Paul

  • T Cell-Independent Antigens Type 2

    James J. Mond;Andrew Lees;Clifford M. Snapper

  • B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms.

    Q Vos;A Lees;Z Q Wu;C M Snapper

  • Towards a comprehensive view of immunoglobulin class switching.

    Clifford M Snapper;James J Mond

  • Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses

    Jorge H. Caamaño;Cheryl A. Rizzo;Stephen K. Durham;Debra S. Barton

  • Differential regulation of IgG1 and IgE synthesis by interleukin 4.

    C M Snapper;F D Finkelman;W E Paul

  • Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

    FD Finkelman;IM Katona;Jr Jf Urban;CM Snapper

  • B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching.

    C. M. Snapper;P. Zelazowski;F. R. Rosas;M. R. Kehry

  • T cell independent antigens.

    James J. Mond;Quirijn Vos;Andrew Lees;Clifford M. Snapper

  • Induction of IgG3 secretion by interferon gamma: a model for T cell-independent class switching in response to T cell-independent type 2 antigens.

    C. M. Snapper;T. M. Mcintyre;R. Mandler;L. M. T. Pecanha

  • Regulation of IgG1 and IgE production by interleukin 4

    Clifford M. Snapper;Fred D. Finkelman;William E. Paul

  • The Immunoglobulin Class Switch: Beyond “Accessibility”

    Clifford M Snapper;Kenneth B Marcu;Piotr Zelazowski

  • Regulation by interferon alpha of immunoglobulin isotype selection and lymphokine production in mice.

    Fred D. Finkelman;Antonela Svetic;Ion Gresser;Clifford Snapper

  • A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens.

    C M Snapper;J J Mond

  • Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells.

    Tina M. McIntyre;Dennis R. Klinman;Paul B Rothman;Michelle Lugo

  • Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms.

    Jesus Colino;Yi Shen;Clifford M. Snapper

  • Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases

    Xinle Cui;Xinle Cui;Clifford M. Snapper

  • Novel in vitro model for high-rate IgA class switching.

    T M McIntyre;M R Kehry;C M Snapper

  • IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predominantly through sequential switching

    Raya Mandler;Fred D. Finkelman;Alan David Levine;Clifford M. Snapper

  • B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching

    C M Snapper;F R Rosas;P Zelazowski;M A Moorman

  • Exosomes from Bone Marrow Dendritic Cells Pulsed with Diphtheria Toxoid Preferentially Induce Type 1 Antigen-Specific IgG Responses in Naive Recipients in the Absence of Free Antigen

    Jesus Colino;Clifford M. Snapper

Frequent Co-Authors

James J. Mond
James J. Mond Uniformed Services University of the Health Sciences
Fred D. Finkelman
Fred D. Finkelman University of Cincinnati
Marilyn R. Kehry
Marilyn R. Kehry Boehringer Ingelheim (Germany)
William C. Gause
William C. Gause Rutgers, The State University of New Jersey
Dennis M. Klinman
Dennis M. Klinman National Institutes of Health
William E. Paul
William E. Paul National Institute of Allergy and Infectious Diseases
David Baltimore
David Baltimore California Institute of Technology
James C. Paton
James C. Paton University of Adelaide
Stuart P. Adler
Stuart P. Adler Virginia Commonwealth University
Charles R. Maliszewski
Charles R. Maliszewski Amgen (United States)

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