World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
111
Citations
54410
World Ranking
837
National Ranking
83

Medicine

D-Index
114
Citations
58292
World Ranking
4660
National Ranking
457

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Diana Eccles is affiliated with the University of Southampton in the United Kingdom. Their research primarily focuses on genetics, cancer research, and molecular biology within the broader fields of biochemistry, genetics, molecular biology, and medicine.

The scientist's recent publications include:

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses, 2020, Nature Genetics
  • Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial, 2020, The Lancet
  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, 2020, Nature Genetics
  • A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study, 2021, The Lancet Oncology
  • Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study, 2022, British Journal of Sports Medicine

Diana Eccles has frequently collaborated with other scientists, including:

  • D. Gareth Evans
  • Peter A. Fasching
  • Manjeet K. Bolla
  • Irene L. Andrulis
  • Marc Tischkowitz

Their work appears often in the following publication venues:

  • Journal of Medical Genetics (11 publications)
  • UNC Libraries (10 publications)
  • Genetics in Medicine (9 publications)
  • Breast Cancer Research (8 publications)
  • British Journal of Cancer (5 publications)

The scientist's subfields of study cover areas such as:

  • Genetics
  • Cancer Research
  • Molecular Biology
  • Oncology
  • Pathology and Forensic Medicine

Main topics of research include:

  • BRCA gene mutations in cancer
  • Genetic Associations and Epidemiology
  • Cancer Genomics and Diagnostics
  • Breast Cancer Treatment Studies
  • Genetic factors in colorectal cancer
  • Nutrition, Genetics, and Disease
  • Genomics and Rare Diseases

Best Publications

  • Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies

    A. Antoniou;P.D.P. Pharoah;S. Narod;H.A. Risch

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

    Hanne Meijers-Heijboer;Ans van den Ouweland;Jan Klijn;Marijke Wasielewski

  • PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

    Nazneen Rahman;Sheila Seal;Deborah Thompson;Patrick Kelly

  • Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE

    Nasim Mavaddat;Susan Peock;Debra Frost;Steve Ellis

  • Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results

    Sharon E. Plon;Diana M. Eccles;Douglas Easton;William D. Foulkes

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

    Ganna Chornokur;Hui-Yi Lin;Jonathan P. Tyrer;Kate Lawrenson

  • ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles

    Anthony Renwick;Deborah Thompson;Sheila Seal;Patrick Kelly

  • Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer

    Elena Castro;Chee Goh;David Olmos;Ed Saunders

  • Genome-wide association study identifies five new breast cancer susceptibility loci

    Clare Turnbull;Shahana Ahmed;Jonathan Morrison;David Pernet

  • Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

    Sheila Seal;Deborah Thompson;Anthony Renwick;Anna Elliott

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • Inherited Mutations in 17 Breast Cancer Susceptibility Genes Among a Large Triple-Negative Breast Cancer Cohort Unselected for Family History of Breast Cancer

    Fergus J. Couch;Steven N. Hart;Priyanka Sharma;Amanda Ewart Toland

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.

    A C Antoniou;A P Cunningham;J Peto;D G Evans

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Douglas F. Easton
Douglas F. Easton University of Cambridge
D. Gareth Evans
D. Gareth Evans University of Manchester
Heli Nevanlinna
Heli Nevanlinna University of Helsinki
Melissa C. Southey
Melissa C. Southey Monash University
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Fergus J. Couch
Fergus J. Couch Mayo Clinic

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