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Biology and Biochemistry

D-Index
78
Citations
19946
World Ranking
4592
National Ranking
341

Overview

Thilo Stehle is affiliated with the University of Tübingen in Germany. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions particularly in molecular biology, oncology, infectious diseases, genetics, and immunology.

The primary focus of Stehle's work encompasses virus-based gene therapy research, bacteriophages and microbial interactions, SARS-CoV-2 and COVID-19 research, enzyme structure and function, herpesvirus infections and treatments, peptidase inhibition and analysis, and biochemical and structural characterization.

Frequent co-authors collaborating with Stehle include:

  • Georg Zocher
  • Jason Stahlecker
  • Frank M. Boeckler
  • Michael Strebl
  • Niklas Arnberg

Stehle has published extensively in several scientific venues, with the most common publication sources being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Proceedings of the National Academy of Sciences
  • Journal of Medicinal Chemistry
  • Crystal Growth & Design

Selected recent papers by Thilo Stehle include:

  • Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46, 2020, Proceedings of the National Academy of Sciences
  • NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies, 2021, EMBO Reports
  • Principles and Applications of CF2X Moieties as Unconventional Halogen Bond Donors in Medicinal Chemistry, Chemical Biology, and Drug Discovery, 2023, Journal of Medicinal Chemistry
  • Protein Crystallization in the Presence of a Metastable Liquid-Liquid Phase Separation, 2020, Crystal Growth & Design
  • Cell wall glycosylation in Staphylococcus aureus: targeting the tar glycosyltransferases, 2021, Current Opinion in Structural Biology

Best Publications

  • Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

    Jian-Ping Xiong;Thilo Stehle;Rongguang Zhang;Andrzej Joachimiak

  • Crystal Structure of the Extracellular Segment of Integrin αVβ3

    Jian-Ping Xiong;Thilo Stehle;Beate Diefenbach;Rongguang Zhang

  • Gangliosides are receptors for murine polyoma virus and SV40.

    Billy Tsai;Joanna M. Gilbert;Thilo Stehle;Wayne Lencer

  • Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila

    Christine Kocks;Ju Hyun Cho;Nadine Nehme;Johanna Ulvila

  • The sweet spot: defining virus–sialic acid interactions

    Jennifer E. Stencel-Baerenwald;Kerstin Reiss;Dirk M. Reiter;Thilo Stehle

  • Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment

    Thilo Stehle;Youwei Yan;Thomas L. Benjamin;Stephen C. Harrison;Stephen C. Harrison

  • The structure of simian virus 40 refined at 3.1 A resolution.

    Thilo Stehle;Steven J Gamblin;Youwei Yan;Stephen C Harrison

  • Structural basis for sialic acid–mediated self-recognition by complement factor H

    Baerbel S. Blaum;Jonathan P. Hannan;Andrew P. Herbert;David Kavanagh

  • New insights into the structural basis of integrin activation

    Jian-Ping Xiong;Thilo Stehle;Simon L. Goodman;M. Amin Arnaout

  • A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1

    José M. Casasnovas;Thilo Stehle;Jin-huan Liu;Jia-huai Wang

  • Crystal structure of reovirus attachment protein σ1 reveals evolutionary relationship to adenovirus fiber

    James D. Chappell;Andrea E. Prota;Terence S. Dermody;Thilo Stehle

  • Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry

    Xiaojiang S. Chen;Thilo Stehle;Stephen C. Harrison

  • Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments

    Thilo Stehle;Stephen C Harrison

  • In vivo protein crystallization opens new routes in structural biology

    Rudolf Koopmann;Karolina Cupelli;Lars Redecke;Karol Nass

  • High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding.

    Thilo Stehle;Stephen C. Harrison

  • The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis.

    Emma C Nilsson;Rickard J Storm;Johannes Bauer;Susanne M C Johansson

  • Structure-Function Analysis of the Human JC Polyomavirus Establishes the LSTc Pentasaccharide as a Functional Receptor Motif

    Ursula Neu;Melissa S. Maginnis;Angelina S. Palma;Luisa J. Ströh

  • The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

    Ute Metzger;Christoph Schall;Georg Zocher;Inge Unsöld

  • Crystal structure of two CD46 domains reveals an extended measles virus‐binding surface

    José M. Casasnovas;Mykol Larvie;Thilo Stehle

  • Structural basis of GM1 ganglioside recognition by simian virus 40

    Ursula Neu;Karin Woellner;Guenter Gauglitz;Thilo Stehle;Thilo Stehle

Frequent Co-Authors

Terence S. Dermody
Terence S. Dermody University of Pittsburgh
Ten Feizi
Ten Feizi Imperial College London
Stephen C. Harrison
Stephen C. Harrison Harvard University
Shu-Ming Li
Shu-Ming Li Philipp University of Marburg
Walter J. Atwood
Walter J. Atwood Brown University
Friedrich Götz
Friedrich Götz University of Tübingen
Christian Hertweck
Christian Hertweck Friedrich Schiller University Jena
Robert L. Garcea
Robert L. Garcea University of Colorado Boulder
Frank Schreiber
Frank Schreiber University of Tübingen
Andreas Peschel
Andreas Peschel University of Tübingen

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