D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 86 Citations 32,334 233 World Ranking 7237 National Ranking 336

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Internal medicine
  • Enzyme

Angelika Bierhaus focuses on Internal medicine, Endocrinology, RAGE, Receptor and Glycation. Her Internal medicine research includes themes of Molecular biology, Peripheral blood mononuclear cell and Electrophoretic mobility shift assay. As a member of one scientific family, Angelika Bierhaus mostly works in the field of Endocrinology, focusing on Transcription factor and, on occasion, Gene expression, Transgene and Messenger RNA.

Her RAGE study combines topics from a wide range of disciplines, such as Inflammation, Immunology and HMGB1. Her Receptor study integrates concerns from other disciplines, such as In vitro and ADAM10. Angelika Bierhaus has researched Glycation in several fields, including Antioxidant, Downregulation and upregulation, Immunoglobulin superfamily and Pathogenesis.

Her most cited work include:

  • RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. (1596 citations)
  • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. (1074 citations)
  • Understanding RAGE, the receptor for advanced glycation end products (945 citations)

What are the main themes of her work throughout her whole career to date?

Her primary scientific interests are in Internal medicine, Endocrinology, RAGE, Diabetes mellitus and Receptor. Her research in Internal medicine focuses on subjects like Type 2 diabetes, which are connected to Adiponectin. Her Endocrinology research incorporates themes from Peripheral blood mononuclear cell and Transcription factor.

Her RAGE study integrates concerns from other disciplines, such as Inflammation, Immunology, HMGB1 and Cancer research. Her work in Immunology tackles topics such as Cell biology which are related to areas like Tissue factor. Her Receptor research is multidisciplinary, incorporating perspectives in Downregulation and upregulation and Pathology.

She most often published in these fields:

  • Internal medicine (52.26%)
  • Endocrinology (44.84%)
  • RAGE (27.74%)

What were the highlights of her more recent work (between 2011-2017)?

  • Internal medicine (52.26%)
  • Endocrinology (44.84%)
  • RAGE (27.74%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Internal medicine, Endocrinology, RAGE, Diabetes mellitus and Glycation. Angelika Bierhaus interconnects Surgery, Type 2 diabetes and Cardiology in the investigation of issues within Internal medicine. Her RAGE study combines topics in areas such as Inflammation, Immunology, Kidney and Pathology.

Her work carried out in the field of Inflammation brings together such families of science as Meningitis and Cancer research. Her Diabetes mellitus research includes themes of Blood pressure, Apolipoprotein E, Methylglyoxal and Renal function. Her work deals with themes such as Oxidative stress, Neuroprotection, Insulin resistance and Cell biology, which intersect with Glycation.

Between 2011 and 2017, her most popular works were:

  • Methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy (315 citations)
  • Methylglyoxal Activates Nociceptors through Transient Receptor Potential Channel A1 (TRPA1) A POSSIBLE MECHANISM OF METABOLIC NEUROPATHIES (128 citations)
  • Sustained Effects of a Mindfulness-Based Stress-Reduction Intervention in Type 2 Diabetic Patients: Design and first results of a randomized controlled trial (the Heidelberger Diabetes and Stress-Study) (95 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

Angelika Bierhaus mainly investigates Internal medicine, Endocrinology, Diabetes mellitus, Methylglyoxal and RAGE. Angelika Bierhaus has included themes like Type 2 diabetes and Urology in her Internal medicine study. The Endocrinology study which covers Receptor that intersects with Immune system.

Her Methylglyoxal research includes elements of Proinflammatory cytokine, Neuropathic pain and Intracellular. In her research, Immunology is intimately related to Experimental pathology, which falls under the overarching field of Proinflammatory cytokine. Her studies deal with areas such as Inflammation, Microglia, HMGB1 and Cell biology as well as RAGE.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.

Marion A Hofmann;Steven Drury;Caifeng Fu;Wu Qu.
Cell (1999)

2076 Citations

Understanding RAGE, the receptor for advanced glycation end products

Angelika Bierhaus;Per M. Humpert;Michael Morcos;Thoralf Wendt.
Journal of Molecular Medicine (2005)

1481 Citations

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.

Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen.
Nature Immunology (2007)

1419 Citations

Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB

Angelika Bierhaus;Stephan Schiekofer;Stephan Schiekofer;Markus Schwaninger;Martin Andrassy;Martin Andrassy.
Diabetes (2001)

1011 Citations

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

Hans Peter Hammes;Xueliang Du;Diane Edelstein;Tetsuya Taguchi.
Nature Medicine (2003)

980 Citations

A mechanism converting psychosocial stress into mononuclear cell activation.

Angelika Bierhaus;Jutta Wolf;Martin Andrassy;Nicolas Rohleder.
Proceedings of the National Academy of Sciences of the United States of America (2003)

949 Citations

AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept

Angelika Bierhaus;Marion A Hofmann;Reinhard Ziegler;Peter P Nawroth.
Cardiovascular Research (1998)

797 Citations

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

Huan Yang;Hulda S. Hreggvidsdottir;Karin Palmblad;Haichao Wang.
Proceedings of the National Academy of Sciences of the United States of America (2010)

745 Citations

RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.

Thoralf M. Wendt;Nozomu Tanji;Jiancheng Guo;Thomas R. Kislinger.
American Journal of Pathology (2003)

724 Citations

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

Birgit Liliensiek;Birgit Liliensiek;Markus A. Weigand;Angelika Bierhaus;Werner Nicklas.
Journal of Clinical Investigation (2004)

680 Citations

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