World's Best Scientists 2026 revealed!
Angelika Bierhaus

Angelika Bierhaus

D-Index & Metrics

Medicine

D-Index
98
Citations
40806
World Ranking
8846
National Ranking
492

Overview

Angelika Bierhaus was affiliated with Heidelberg University in Germany. Their research contributions focused primarily on the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology.

The scientist's work encompassed several subfields, notably Clinical Biochemistry and Applied Microbiology and Biotechnology. Within these areas, their research addressed specific topics including Advanced Glycation End Products research, and Tannin, Tannase and Anticancer Activities.

Angelika Bierhaus had a documented publication record that includes papers published in the journal Cell Death and Differentiation. Among their recent contributions was a 2025 publication titled Correction to: The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival in the same journal.

Their collaborative work involved frequent co-authorship with several researchers:

  • Rui Kang
  • Daolin Tang
  • Nicole E. Schapiro
  • Kristen M. Livesey
  • Adam M. Farkas

Angelika Bierhaus's scholarly activity included contributions to topics surrounding the biochemical mechanisms of disease and cellular survival pathways, reflecting their involvement in both molecular biology and microbiology related investigations.

Best Publications

  • RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.

    Marion A Hofmann;Steven Drury;Caifeng Fu;Wu Qu

  • Understanding RAGE, the receptor for advanced glycation end products

    Angelika Bierhaus;Per M. Humpert;Michael Morcos;Thoralf Wendt

  • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.

    Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen

  • Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

    Hans Peter Hammes;Xueliang Du;Diane Edelstein;Tetsuya Taguchi

  • A mechanism converting psychosocial stress into mononuclear cell activation.

    Angelika Bierhaus;Jutta Wolf;Martin Andrassy;Nicolas Rohleder

  • Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB

    Angelika Bierhaus;Stephan Schiekofer;Stephan Schiekofer;Markus Schwaninger;Martin Andrassy;Martin Andrassy

  • A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

    Huan Yang;Hulda S. Hreggvidsdottir;Karin Palmblad;Haichao Wang

  • AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept

    Angelika Bierhaus;Marion A Hofmann;Reinhard Ziegler;Peter P Nawroth

  • RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.

    Thoralf M. Wendt;Nozomu Tanji;Jiancheng Guo;Thomas R. Kislinger

  • High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

    Martin Andrassy;Hans C. Volz;John C. Igwe;Benjamin Funke

  • The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins A Novel Pathway for Inflammatory Cell Recruitment

    Triantafyllos Chavakis;Angelika Bierhaus;Nadia Al-Fakhri;Darius Schneider

  • A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

    Angela Raucci;Simona Cugusi;Antonella Antonelli;Silvia M. Barabino

  • Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

    Birgit Liliensiek;Birgit Liliensiek;Markus A. Weigand;Angelika Bierhaus;Werner Nicklas

  • Role of NFkappaB in the mortality of sepsis.

    H Böhrer;F Qiu;T Zimmermann;Y Zhang

  • Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells.

    Angelika Bierhaus;Shlomit Chevion;Shlomit Chevion;Mordechai Chevion;Marion Hofmann

  • Methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

    Angelika Bierhaus;Thomas Fleming;Stoyan Stoyanov;Andreas Leffler;Andreas Leffler

  • RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

    Melinda T. Coughlan;David R. Thorburn;Sally A. Penfold;Sally A. Penfold;Adrienne Laskowski

  • A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin.

    Valeria V Orlova;Eun Young Choi;Changping Xie;Emmanouil Chavakis

  • Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

    Aino Soro-Paavonen;Anna M.D. Watson;Jiaze Li;Karri Paavonen

  • The role of oxidative stress and NF-κB activation in late diabetic complications

    Abdel Khalek Mohamed;Angelika Bierhaus;Stephan Schiekofer;Hans Tritschler

Frequent Co-Authors

Peter P. Nawroth
Peter P. Nawroth Heidelberg University
Reinhard Ziegler
Reinhard Ziegler Heidelberg University
Mark E. Cooper
Mark E. Cooper Monash University
Josephine M. Forbes
Josephine M. Forbes University of Queensland
Erwin Schleicher
Erwin Schleicher University of Ulm
Hugo A. Katus
Hugo A. Katus Heidelberg University
David M. Stern
David M. Stern University of Tennessee Health Science Center
Per-Henrik Groop
Per-Henrik Groop University of Helsinki
Martin Zeier
Martin Zeier University Hospital Heidelberg
Bernd Arnold
Bernd Arnold German Cancer Research Center

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