Angelika Bierhaus focuses on Internal medicine, Endocrinology, RAGE, Receptor and Glycation. Her Internal medicine research includes themes of Molecular biology, Peripheral blood mononuclear cell and Electrophoretic mobility shift assay. As a member of one scientific family, Angelika Bierhaus mostly works in the field of Endocrinology, focusing on Transcription factor and, on occasion, Gene expression, Transgene and Messenger RNA.
Her RAGE study combines topics from a wide range of disciplines, such as Inflammation, Immunology and HMGB1. Her Receptor study integrates concerns from other disciplines, such as In vitro and ADAM10. Angelika Bierhaus has researched Glycation in several fields, including Antioxidant, Downregulation and upregulation, Immunoglobulin superfamily and Pathogenesis.
Her primary scientific interests are in Internal medicine, Endocrinology, RAGE, Diabetes mellitus and Receptor. Her research in Internal medicine focuses on subjects like Type 2 diabetes, which are connected to Adiponectin. Her Endocrinology research incorporates themes from Peripheral blood mononuclear cell and Transcription factor.
Her RAGE study integrates concerns from other disciplines, such as Inflammation, Immunology, HMGB1 and Cancer research. Her work in Immunology tackles topics such as Cell biology which are related to areas like Tissue factor. Her Receptor research is multidisciplinary, incorporating perspectives in Downregulation and upregulation and Pathology.
Her primary areas of investigation include Internal medicine, Endocrinology, RAGE, Diabetes mellitus and Glycation. Angelika Bierhaus interconnects Surgery, Type 2 diabetes and Cardiology in the investigation of issues within Internal medicine. Her RAGE study combines topics in areas such as Inflammation, Immunology, Kidney and Pathology.
Her work carried out in the field of Inflammation brings together such families of science as Meningitis and Cancer research. Her Diabetes mellitus research includes themes of Blood pressure, Apolipoprotein E, Methylglyoxal and Renal function. Her work deals with themes such as Oxidative stress, Neuroprotection, Insulin resistance and Cell biology, which intersect with Glycation.
Angelika Bierhaus mainly investigates Internal medicine, Endocrinology, Diabetes mellitus, Methylglyoxal and RAGE. Angelika Bierhaus has included themes like Type 2 diabetes and Urology in her Internal medicine study. The Endocrinology study which covers Receptor that intersects with Immune system.
Her Methylglyoxal research includes elements of Proinflammatory cytokine, Neuropathic pain and Intracellular. In her research, Immunology is intimately related to Experimental pathology, which falls under the overarching field of Proinflammatory cytokine. Her studies deal with areas such as Inflammation, Microglia, HMGB1 and Cell biology as well as RAGE.
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RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides.
Marion A Hofmann;Steven Drury;Caifeng Fu;Wu Qu.
Cell (1999)
Understanding RAGE, the receptor for advanced glycation end products
Angelika Bierhaus;Per M. Humpert;Michael Morcos;Thoralf Wendt.
Journal of Molecular Medicine (2005)
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen.
Nature Immunology (2007)
Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB
Angelika Bierhaus;Stephan Schiekofer;Stephan Schiekofer;Markus Schwaninger;Martin Andrassy;Martin Andrassy.
Diabetes (2001)
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy
Hans Peter Hammes;Xueliang Du;Diane Edelstein;Tetsuya Taguchi.
Nature Medicine (2003)
A mechanism converting psychosocial stress into mononuclear cell activation.
Angelika Bierhaus;Jutta Wolf;Martin Andrassy;Nicolas Rohleder.
Proceedings of the National Academy of Sciences of the United States of America (2003)
AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
Angelika Bierhaus;Marion A Hofmann;Reinhard Ziegler;Peter P Nawroth.
Cardiovascular Research (1998)
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
Huan Yang;Hulda S. Hreggvidsdottir;Karin Palmblad;Haichao Wang.
Proceedings of the National Academy of Sciences of the United States of America (2010)
RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.
Thoralf M. Wendt;Nozomu Tanji;Jiancheng Guo;Thomas R. Kislinger.
American Journal of Pathology (2003)
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
Birgit Liliensiek;Birgit Liliensiek;Markus A. Weigand;Angelika Bierhaus;Werner Nicklas.
Journal of Clinical Investigation (2004)
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