Niels P. Riksen

Best Publications

• Defining trained immunity and its role in health and disease

  Mihai G. Netea;Mihai G. Netea;Jorge Domínguez-Andrés;Luis B. Barreiro;Luis B. Barreiro;Triantafyllos Chavakis;Triantafyllos Chavakis

  2315
  Citations

• Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

  Anette Christ;Anette Christ;Patrick Günther;Mario A.R. Lauterbach;Peter Duewell

  993
  Citations

• Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.

  Rob J.W. Arts;Boris Novakovic;Rob ter Horst;Agostinho Carvalho

  830
  Citations

• Metabolic Induction of Trained Immunity through the Mevalonate Pathway

  Siroon Bekkering;Rob J.W. Arts;Boris Novakovic;Ioannis Kourtzelis

  708
  Citations

• Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes

  Siroon Bekkering;Jessica Quintin;Leo A.B. Joosten;Jos W.M. van der Meer

  584
  Citations

• Trained immunity, tolerance, priming and differentiation: distinct immunological processes.

  Maziar Divangahi;Peter Aaby;Shabaana A. Khader;Luis B. Barreiro

  548
  Citations

• Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

  Fleur M. van der Valk;Siroon Bekkering;Jeffrey Kroon;Calvin Yeang

  502
  Citations

• In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes

  Siroon Bekkering;Bastiaan A. Blok;Bastiaan A. Blok;Bastiaan A. Blok;Leo A. B. Joosten;Niels P. Riksen

  347
  Citations

• Role of gut microbiota in chronic low-grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies

  I. C. L. van den Munckhof;A. Kurilshikov;R. ter Horst;N. P. Riksen

  269
  Citations

• Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology.

  Christoph Maack;Michael Lehrke;Johannes Backs;Frank R. Heinzel

  237
  Citations

• Epigenetics and Trained Immunity

  Charlotte D.C.C. van der Heijden;Marlies P. Noz;Leo A.B. Joosten;Mihai G. Netea;Mihai G. Netea

  209
  Citations

• Acute and long-term cardiovascular effects of coffee: implications for coronary heart disease.

  Niels P. Riksen;Gerard A. Rongen;Paul Smits

  207
  Citations

• Trained Immunity: Reprogramming Innate Immunity in Health and Disease.

  Siroon Bekkering;Jorge Domínguez-Andrés;Leo A B Joosten;Niels P Riksen

  205
  Citations

• Trained immunity: A smart way to enhance innate immune defence.

  Jos W.M. van der Meer;Leo A.B. Joosten;Niels Riksen;Mihai G. Netea

  195
  Citations

• Specific and Complex Reprogramming of Cellular Metabolism in Myeloid Cells during Innate Immune Responses

  Rinke Stienstra;Rinke Stienstra;Romana T. Netea-Maier;Niels P. Riksen;Leo A.B. Joosten

  194
  Citations

• Monocyte and macrophage immunometabolism in atherosclerosis.

  Laszlo Groh;Samuel T. Keating;Leo A. B. Joosten;Mihai G. Netea;Mihai G. Netea

  194
  Citations

• Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo

  Siroon Bekkering;Inge van den Munckhof;Tim Nielen;Evert Lamfers

  189
  Citations

• Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction.

  Lara S F Konijnenberg;Peter Damman;Dirk J Duncker;Robert A Kloner;Robert A Kloner

  181
  Citations

• Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk.

  Alexander Kurilshikov;Inge Cl van den Munckhof;Lianmin Chen;Marc Jan Bonder

  175
  Citations

• Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.

  Siroon Bekkering;Siroon Bekkering;Lotte C.A. Stiekema;Sophie Bernelot Moens;Simone L. Verweij

  128
  Citations