His main research concerns Immunology, Innate immune system, Tuberculosis, Immunity and Vaccination. His Immunology study frequently draws connections between related disciplines such as Virology. His Innate immune system research incorporates elements of Interferon and Glutaminolysis.
The various areas that Reinout van Crevel examines in his Tuberculosis study include Diabetes mellitus, Type 2 diabetes and Internal medicine. Reinout van Crevel combines subjects such as Tuberculosis vaccines, Heterologous, Metabolic pathway, Monocyte and Epigenetics with his study of Immunity. His work in the fields of Pattern recognition receptor overlaps with other areas such as Nonsynonymous substitution.
His primary scientific interests are in Tuberculosis, Immunology, Internal medicine, Mycobacterium tuberculosis and Immunity. His research integrates issues of Diabetes mellitus, Pediatrics and Intensive care medicine in his study of Tuberculosis. His work on Virology expands to the thematically related Immunology.
His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology and Rifampicin. His Mycobacterium tuberculosis research is multidisciplinary, relying on both Drug resistance, Microbiology, Pattern recognition receptor, Proinflammatory cytokine and Genetic variation. He works mostly in the field of Immunity, limiting it down to topics relating to Vaccination and, in certain cases, Pandemic, as a part of the same area of interest.
Tuberculosis, Immunology, Immunity, Internal medicine and Vaccination are his primary areas of study. He has included themes like Diabetes mellitus, Disease and Intensive care medicine in his Tuberculosis study. In general Immunology study, his work on Immune system, Cytokine, Myeloid and Monocyte often relates to the realm of Myelopoiesis, thereby connecting several areas of interest.
His Immunity research includes themes of Reprogramming, Cell biology, BCG vaccine, Innate immune system and Bone marrow. Within one scientific family, Reinout van Crevel focuses on topics pertaining to Rifampicin under Internal medicine, and may sometimes address concerns connected to Tolerability, Isoniazid and Virology. The Vaccination study combines topics in areas such as Pandemic and Priming.
Reinout van Crevel mainly investigates Immunology, Immunity, Vaccination, Tuberculosis and Mycobacterium tuberculosis. His study in Innate immune system, Immune system, Cytokine, Monocyte and BCG vaccine are all subfields of Immunology. His study in Innate immune system is interdisciplinary in nature, drawing from both Heterologous and Bone marrow.
His Vaccination research includes elements of Acquired immune system, Priming, Antigen and Adverse effect. He works mostly in the field of Tuberculosis, limiting it down to topics relating to Internal medicine and, in certain cases, Rifampicin and Tuberculous meningitis. His Mycobacterium tuberculosis research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine, Ex vivo, DNA methylation and Lymphocytic choriomeningitis.
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Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
Johanneke Kleinnijenhuis;Jessica Quintin;Frank Preijers;Leo A. B. Joosten.
Proceedings of the National Academy of Sciences of the United States of America (2012)
BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity
Rob J.W. Arts;Simone J.C.F.M. Moorlag;Boris Novakovic;Yang Li.
(2018)
Innate immune recognition of Mycobacterium tuberculosis.
Johanneke Kleinnijenhuis;Marije Oosting;Leo A. B. Joosten;Mihai G. Netea.
Clinical & Developmental Immunology (2011)
The Effect of Type 2 Diabetes Mellitus on the Presentation and Treatment Response of Pulmonary Tuberculosis
Bachti Alisjahbana;Edhyana Sahiratmadja;Erni J. Nelwan;Anugrah Maya Purwa.
Clinical Infectious Diseases (2007)
Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Rob J.W. Arts;Boris Novakovic;Rob ter Horst;Agostinho Carvalho.
Cell Metabolism (2016)
Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity.
Johanneke Kleinnijenhuis;Jessica Quintin;Frank Preijers;Christine Stabell Benn.
Journal of Innate Immunity (2014)
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.
Gerben Ferwerda;Stephen E. Girardin;Bart Jan Kullberg;Lionel Le Bourhis.
PLOS Pathogens (2005)
BCG-induced trained immunity in NK cells: role for non-specific protection to infection
Johanneke Kleinnijenhuis;Jessica Quintin;Frank Preijers;Leo A. B. Joosten.
Clinical Immunology (2014)
Immunometabolic pathways in BCG-induced trained immunity
Rob J.W. Arts;Agostinho Carvalho;Claudia La Rocca;Carla Palma.
Cell Reports (2016)
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans
Bart Ferwerda;Matthew B. B. McCall;Santos Alonso;Evangelos J. Giamarellos-Bourboulis.
Proceedings of the National Academy of Sciences of the United States of America (2007)
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