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Graham Dellaire

Graham Dellaire

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11440
World Ranking
14424
National Ranking
506

Overview

Graham Dellaire is affiliated with Dalhousie University in Canada and has an extensive research portfolio primarily in biochemistry, genetics, and molecular biology. Their work spans 92 publications in these areas, complemented by 30 publications in medicine. The subfields of study associated with their research include molecular biology, biochemistry, cell biology, infectious diseases, and physiology.

Research topics that feature prominently in Dellaire's work focus on RNA modifications and cancer, lipid metabolism and biosynthesis, nuclear structure and function, RNA research and splicing, retinoids in leukemia and cellular processes, protein degradation and inhibitors, and genomics related to phytochemicals and oxidative stress.

Frequent publication venues for Dellaire's work include bioRxiv (Cold Spring Harbor Laboratory), The FASEB Journal, Journal of Thoracic Oncology, Antioxidants, and Journal of Biological Chemistry. These venues reflect the interdisciplinary nature of their research spanning basic biological sciences and clinical applications.

Selected recent papers authored by Dellaire or within their collaborative network are as follows:

  • Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management? (2020, Antioxidants)
  • Role of Dietary Antioxidants in p53-Mediated Cancer Chemoprevention and Tumor Suppression (2021, Oxidative Medicine and Cellular Longevity)
  • Pandemic danger to the deep: The risk of marine mammals contracting SARS-CoV-2 from wastewater (2020, The Science of The Total Environment)
  • Lions, tigers and kittens too: ACE2 and susceptibility to COVID-19 (2020, Evolution Medicine and Public Health)
  • Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1 (2020, Life Science Alliance)

Dellaire collaborates frequently with several co-authors, notably Jayme Salsman, Sabateeshan Mathavarajah, Neale D. Ridgway, Michael McPhee, and Elias B. Habib. These collaborations have resulted in multiple joint publications, underpinning a collaborative research environment.

Best Publications

  • Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

    Michael J. Kruhlak;Arkady Celeste;Graham Dellaire;Oscar Fernandez-Capetillo

  • PML nuclear bodies: dynamic sensors of DNA damage and cellular stress.

    Graham Dellaire;David P. Bazett-Jones

  • A mechanism for the suppression of homologous recombination in G1 cells

    Alexandre Orthwein;Sylvie M. Noordermeer;Marcus D. Wilson;Sébastien Landry

  • An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin.

    Nadine Collins;Raymond A. Poot;Iwao Kukimoto;Custodia García-Jiménez

  • Expression patterns and post-translational modifications associated with mammalian histone H3 variants.

    Sandra B. Hake;Benjamin A. Garcia;Elizabeth M. Duncan;Monika Kauer

  • Plant flavonoids in cancer chemoprevention: role in genome stability

    Vazhappilly Cijo George;Graham Dellaire;H.P. Vasantha Rupasinghe

  • Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

    Amal M. El-Naggar;Chansey J. Veinotte;Hongwei Cheng;Thomas G.P. Grunewald

  • Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing.

    Jordan Pinder;Jayme Salsman;Graham Dellaire;Graham Dellaire

  • HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins

    Raymond A. Poot;Graham Dellaire;Bastian B. Hülsmann;Margaret A. Grimaldi

  • Zebrafish xenografts as a tool for in vivo studies on human cancer

    Martina Konantz;Tugce B. Balci;Udo F. Hartwig;Graham Dellaire

  • Application of Quantum Dots as Probes for Correlative Fluorescence, Conventional, and Energy-filtered Transmission Electron Microscopy

    Rozalia Nisman;Graham Dellaire;Ying Ren;Ren Li

  • A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.

    Marta Castroviejo-Bermejo;Cristina Cruz;Alba Llop-Guevara;Sara Gutiérrez-Enríquez

  • Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR

    Graham Dellaire;Reagan W. Ching;Kashif Ahmed;Farid Jalali

  • Nuclear position dictates DNA repair pathway choice

    Charlène Lemaître;Anastazja Grabarz;Katerina Tsouroula;Leonid Andronov

  • Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era.

    Chansey J. Veinotte;Chansey J. Veinotte;Graham Dellaire;Jason N. Berman

  • PML bodies: a meeting place for genomic loci?

    Reagan W. Ching;Graham Dellaire;Christopher H. Eskiw;David P. Bazett-Jones

  • Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly

    Christopher H. Eskiw;Graham Dellaire;Joe S. Mymryk;David P. Bazett-Jones

  • Coupling of Homologous Recombination and the Checkpoint by ATR.

    Rémi Buisson;Joshi Niraj;Amélie Rodrigue;Chu Kwen Ho

  • Precision genome editing in the CRISPR era.

    Jayme Salsman;Graham Dellaire;Graham Dellaire

  • Heterochromatin and the DNA damage response: the need to relaxThis paper is one of a selection of papers in a Special Issue entitled 31st Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

    Kendra L. CannK.L. Cann;Graham DellaireG. Dellaire;Graham DellaireG. Dellaire

Frequent Co-Authors

David P. Bazett-Jones
David P. Bazett-Jones University of Calgary
Jean-Yves Masson
Jean-Yves Masson Université Laval
Raul Mostoslavsky
Raul Mostoslavsky Harvard University
David M. Langenau
David M. Langenau Harvard University
Robert G. Bristow
Robert G. Bristow University of Manchester
Wan L. Lam
Wan L. Lam BC Cancer Research Centre
Wendy A. Bickmore
Wendy A. Bickmore University of Edinburgh
John M. Asara
John M. Asara Beth Israel Deaconess Medical Center
H.P. Vasantha Rupasinghe
H.P. Vasantha Rupasinghe Dalhousie University
Andrew J. Roger
Andrew J. Roger Dalhousie University

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