2022 - Research.com Rising Star of Science Award
Tetsushi Sakuma focuses on Genetics, Transcription activator-like effector nuclease, Genome editing, CRISPR and Cell biology. His study in Genome, Gene, Genome engineering, Electroporation and Exon is done as part of Genetics. His study in Transcription activator-like effector nuclease is interdisciplinary in nature, drawing from both Transfection, TAL effector, Gene targeting, Computational biology and Effector.
The concepts of his Genome editing study are interwoven with issues in Knockout rat and Zinc finger. In his study, DNA repair and Zebrafish is strongly linked to Homologous recombination, which falls under the umbrella field of CRISPR. His Cell biology research incorporates themes from Induced pluripotent stem cell and Transplantation.
The scientist’s investigation covers issues in Cell biology, Genetics, Gene, Genome editing and Transcription activator-like effector nuclease. In his research, Cellular differentiation is intimately related to Induced pluripotent stem cell, which falls under the overarching field of Cell biology. His work in Genome editing covers topics such as Computational biology which are related to areas like DNA.
His work carried out in the field of Transcription activator-like effector nuclease brings together such families of science as Transfection, Gene knockout, Molecular biology, Gene targeting and Transcription. His Transcription research integrates issues from Nuclease and Effector. His studies in CRISPR integrate themes in fields like Functional genomics, Gene knockin and Homologous recombination.
Tetsushi Sakuma mainly focuses on Cell biology, Gene, Biochemistry, Cell and Cancer research. When carried out as part of a general Cell biology research project, his work on Mitochondrion is frequently linked to work in Swimming behaviour, therefore connecting diverse disciplines of study. His work in the fields of Gene, such as A-DNA, Mutagenesis, Transcription factor and Ciona intestinalis, overlaps with other areas such as Fusion.
Ciona intestinalis is a primary field of his research addressed under Genetics. His Molecular breeding research focuses on subjects like Algae, which are linked to Transcription activator-like effector nuclease. His biological study spans a wide range of topics, including Epigenome editing, Computational biology and Cas9.
His primary areas of study are Cell biology, Ciona, Gene, Ciona intestinalis and Endoplasmic reticulum. His Cell biology research incorporates elements of Neuropeptide and Tyrosine hydroxylase. Tetsushi Sakuma interconnects Hypothalamus, Excitatory postsynaptic potential, Chordate and Neurotransmitter in the investigation of issues within Ciona.
His research combines Pseudopodia and Gene. His Ciona intestinalis study results in a more complete grasp of Genetics. His Endoplasmic reticulum study combines topics in areas such as Mannosidase, Protein degradation and Transfection.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9
Hongmei Lisa Li;Naoko Fujimoto;Noriko Sasakawa;Saya Shirai.
Stem cell reports (2015)
Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9.
Shota Nakade;Takuya Tsubota;Yuto Sakane;Satoshi Kume.
Nature Communications (2014)
Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells.
Kotaro Sasaki;Shihori Yokobayashi;Tomonori Nakamura;Ikuhiro Okamoto.
Cell Stem Cell (2015)
Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system
Tetsushi Sakuma;Ayami Nishikawa;Satoshi Kume;Kazuaki Chayama.
Scientific Reports (2015)
MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
Tetsushi Sakuma;Shota Nakade;Yuto Sakane;Ken-Ichi T Suzuki.
Nature Protocols (2016)
Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
Tomomi Aida;Keiho Chiyo;Takako Usami;Harumi Ishikubo.
Genome Biology (2015)
Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity.
Tetsushi Sakuma;Hiroshi Ochiai;Takehito Kaneko;Tomoji Mashimo.
Scientific Reports (2013)
Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish
Yu Hisano;Tetsushi Sakuma;Shota Nakade;Rie Ohga.
Scientific Reports (2015)
Efficient TALEN construction and evaluation methods for human cell and animal applications
Tetsushi Sakuma;Sayaka Hosoi;Knut Woltjen;Ken Ichi Suzuki.
Genes to Cells (2013)
Sterol Side Chain Reductase 2 Is a Key Enzyme in the Biosynthesis of Cholesterol, the Common Precursor of Toxic Steroidal Glycoalkaloids in Potato
Satoru Sawai;Kiyoshi Ohyama;Shuhei Yasumoto;Hikaru Seki.
The Plant Cell (2014)
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