What is he best known for?
The fields of study he is best known for:
Tetsushi Sakuma focuses on Genetics, Transcription activator-like effector nuclease, Genome editing, CRISPR and Cell biology.
His study in Genome, Gene, Genome engineering, Electroporation and Exon is done as part of Genetics.
His study in Transcription activator-like effector nuclease is interdisciplinary in nature, drawing from both Transfection, TAL effector, Gene targeting, Computational biology and Effector.
The concepts of his Genome editing study are interwoven with issues in Knockout rat and Zinc finger.
In his study, DNA repair and Zebrafish is strongly linked to Homologous recombination, which falls under the umbrella field of CRISPR.
His Cell biology research incorporates themes from Induced pluripotent stem cell and Transplantation.
His most cited work include:
- Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9 (360 citations)
- Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9. (300 citations)
- Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system (243 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Cell biology, Genetics, Gene, Genome editing and Transcription activator-like effector nuclease.
In his research, Cellular differentiation is intimately related to Induced pluripotent stem cell, which falls under the overarching field of Cell biology.
His work in Genome editing covers topics such as Computational biology which are related to areas like DNA.
His work carried out in the field of Transcription activator-like effector nuclease brings together such families of science as Transfection, Gene knockout, Molecular biology, Gene targeting and Transcription.
His Transcription research integrates issues from Nuclease and Effector.
His studies in CRISPR integrate themes in fields like Functional genomics, Gene knockin and Homologous recombination.
He most often published in these fields:
- Cell biology (34.95%)
- Genetics (33.33%)
- Gene (30.11%)
What were the highlights of his more recent work (between 2019-2021)?
- Cell biology (34.95%)
- Gene (30.11%)
- Biochemistry (5.91%)
In recent papers he was focusing on the following fields of study:
Tetsushi Sakuma mainly focuses on Cell biology, Gene, Biochemistry, Cell and Cancer research.
When carried out as part of a general Cell biology research project, his work on Mitochondrion is frequently linked to work in Swimming behaviour, therefore connecting diverse disciplines of study.
His work in the fields of Gene, such as A-DNA, Mutagenesis, Transcription factor and Ciona intestinalis, overlaps with other areas such as Fusion.
Ciona intestinalis is a primary field of his research addressed under Genetics.
His Molecular breeding research focuses on subjects like Algae, which are linked to Transcription activator-like effector nuclease.
His biological study spans a wide range of topics, including Epigenome editing, Computational biology and Cas9.
Between 2019 and 2021, his most popular works were:
- EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD. (11 citations)
- DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria. (7 citations)
- GABA-Induced GnRH Release Triggers Chordate Metamorphosis (6 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Cell biology, Ciona, Gene, Ciona intestinalis and Endoplasmic reticulum.
His Cell biology research incorporates elements of Neuropeptide and Tyrosine hydroxylase.
Tetsushi Sakuma interconnects Hypothalamus, Excitatory postsynaptic potential, Chordate and Neurotransmitter in the investigation of issues within Ciona.
His research combines Pseudopodia and Gene.
His Ciona intestinalis study results in a more complete grasp of Genetics.
His Endoplasmic reticulum study combines topics in areas such as Mannosidase, Protein degradation and Transfection.
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