World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
62
Citations
28015
World Ranking
3086
National Ranking
1445

Overview

David G. DeNardo is affiliated with Washington University in St. Louis in the United States. Their research focuses broadly on medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. Within these fields, specific areas of study include oncology, immunology, molecular biology, cancer research, and pulmonary and respiratory medicine.

They have contributed significantly to multiple main research topics including cancer immunotherapy and biomarkers, pancreatic and hepatic oncology research, immune cells in cancer, CAR-T cell therapy research, cancer genomics and diagnostics, immunotherapy and immune responses, and cancer cells and metastasis.

David G. DeNardo has published numerous papers in a range of scientific journals. Recent publications include:

  • A framework for advancing our understanding of cancer-associated fibroblasts (2020), published in Nature Reviews. Cancer
  • Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer (2020), published in Cancer Cell
  • Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer (2022), published in Nature Genetics
  • Epigenetic regulation during cancer transitions across 11 tumour types (2023), published in Nature
  • Rethinking immune checkpoint blockade: 'Beyond the T cell' (2021), published in Journal for ImmunoTherapy of Cancer

The venues where David G. DeNardo publishes frequently include Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Cancer Discovery, Clinical Cancer Research, and Cancer Cell. These journals reflect a consistent engagement with cancer-focused and immunology-related scientific communities.

Throughout their career, they have collaborated extensively with several researchers. Their frequent coauthors are:

  • Ryan C. Fields
  • William G. Hawkins
  • Brett L. Knolhoff
  • John Baer
  • Liang-I Kang

Best Publications

  • Macrophages as regulators of tumour immunity and immunotherapy

    David G. DeNardo;Brian Ruffell

  • Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

    David G. DeNardo;David G. DeNardo;Donal J. Brennan;Elton Rexhepaj;Brian Ruffell

  • CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

    David G. DeNardo;Jairo B. Barreto;Pauline Andreu;Lesley Vasquez;Lesley Vasquez

  • CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

    Yu Zhu;Brett L. Knolhoff;Melissa A. Meyer;Timothy M. Nywening

  • Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

    Jonathan B Mitchem;Donal J Brennan;Brett L Knolhoff;Brian A Belt

  • Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

    Hong Jiang;Samarth Hegde;Brett L Knolhoff;Yu Zhu

  • Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression.

    David G DeNardo;Lisa M Coussens

  • Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

    Yu Zhu;John M. Herndon;Dorothy K. Sojka;Ki Wook Kim

  • Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

    Andrew L. Doedens;Christian Stockmann;Mark P. Rubinstein;Debbie Liao

  • Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity.

    David G. DeNardo;Pauline Andreu;Lisa M. Coussens

  • FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis

    Pauline Andreu;Magnus Johansson;Nesrine I. Affara;Ferdinando Pucci

  • Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis

    Dominic E. Sanford;Brian A. Belt;Roheena Z. Panni;Allese Mayer

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

    Megan K. Ruhland;Andrew J. Loza;Aude Helene Capietto;Xianmin Luo

  • Immune cells as mediators of solid tumor metastasis.

    David G. DeNardo;Magnus Johansson;Lisa M. Coussens

  • Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma

    Timothy M Nywening;Brian A Belt;Darren R Cullinan;Roheena Z Panni

  • Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.

    Samarth Hegde;Varintra E. Krisnawan;Brett H. Herzog;Chong Zuo

  • Lymphocytes in cancer development: Polarization towards pro-tumor immunity

    Brian Ruffell;David G. DeNardo;Nesrine I. Affara;Lisa M. Coussens

  • TH2-Polarized CD4+ T Cells and Macrophages Limit Efficacy of Radiotherapy

    Stephen L. Shiao;Brian Ruffell;David G. DeNardo;Bruce A. Faddegon

  • Polarized immune responses differentially regulate cancer development.

    Magnus Johansson;David G. DeNardo;Lisa M. Coussens

  • Paclitaxel therapy promotes breast cancer metastasis in a TLR4-dependent manner.

    Lisa Volk-Draper;Kelly Hall;Caitlin Griggs;Sandeep Rajput

  • Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression

    David G DeNardo;Lisa M Coussens

  • Correction: Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression (Immunity (2017) 47(2) (323–338.e6) (S1074761317303217)(10.1016/j.immuni.2017.07.014))

    Yu Zhu;John M. Herndon;Dorothy K. Sojka;Ki Wook Kim

Frequent Co-Authors

William G. Hawkins
William G. Hawkins Washington University in St. Louis
Lisa M. Coussens
Lisa M. Coussens Oregon Health & Science University
William E. Gillanders
William E. Gillanders Washington University in St. Louis
Roberta Faccio
Roberta Faccio Washington University in St. Louis
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Brian L. West
Brian L. West Daiichi Sankyo (United States)
Samuel Achilefu
Samuel Achilefu Washington University in St. Louis
Susan G. Hilsenbeck
Susan G. Hilsenbeck Baylor College of Medicine
Aviv Regev
Aviv Regev Genentech
Li Ding
Li Ding Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in immunology, pursuing related nursing degrees online can be a strategic step towards a rewarding healthcare career. Many professionals start by exploring online RN programs for non nurses in Florida, which provide foundational nursing skills even without prior healthcare experience.

Once registered nurses, individuals often advance through accelerated nurse practitioner programs. These programs shorten the pathway to becoming a nurse practitioner, allowing quicker entry into specialized roles that intersect with immunology research and clinical practice.

Further specialization is possible with certifications like acute care nurse practitioner certification. This credential enables practitioners to work in critical care settings, which often involve immunological assessments and treatments for complex patient cases.

Understanding the financial outlook is also important. According to dnp salary data, salaries vary significantly by location, reflecting demand and cost of living factors. This insight helps aspiring professionals make informed decisions about their education and career pathways in healthcare.

Best Scientists Citing David G. DeNardo

Trending Scientists

Recently Published Articles