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Ignacio Anegon

Ignacio Anegon

D-Index & Metrics

Immunology

D-Index
72
Citations
17951
World Ranking
2225
National Ranking
87

Overview

Ignacio Anegon is affiliated with Inserm in France and has contributed extensively to research in medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work spans several subfields including molecular biology, immunology, genetics, cardiology and cardiovascular medicine, and surgery.

The main topics of research covered by Ignacio Anegon include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • CAR-T cell therapy research
  • Cardiac Valve Diseases and Treatments
  • Virus-based gene therapy research

Notable recent publications provide insight into the scope and impact of their research. These include:

  • "Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models" (2021), Frontiers in Genetics
  • "Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications" (2021), Frontiers in Immunology
  • "IL-34 and CSF-1, deciphering similarities and differences at steady state and in diseases" (2021), Journal of Leukocyte Biology
  • "Comparison of Human and Experimental Pulmonary Veno-Occlusive Disease" (2020), American Journal of Respiratory Cell and Molecular Biology
  • "Humanization of Immunodeficient Animals for the Modeling of Transplantation, Graft Versus Host Disease, and Regenerative Medicine" (2020), Transplantation

Frequent co-authors who have collaborated with Ignacio Anegon include:

  • Séverine Remy
  • Carole Guillonneau
  • Laurent Tesson
  • Séverine Bézie
  • Nadège Vimond

The scientist has published in various key venues with the highest number of publications found in:

  • Transplantation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Molecular Therapy - Methods & Clinical Development
  • Archives of Cardiovascular Diseases Supplements

Best Publications

  • Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

    Aron M. Geurts;Gregory J. Cost;Yevgeniy Freyvert;Bryan Zeitler

  • Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.

    Dorothée Duluc;Dorothée Duluc;Yves Delneste;Yves Delneste;Fang Tan;Fang Tan;Marie-Pierre Moles

  • Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells.

    Ignacio Anegon;Maria Cristina Cuturi;Giorgio Trinchieri;Bice Perussia

  • A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells.

    Dominique Chabannes;Marcelo Hill;Emmanuel Merieau;Julien Rossignol

  • Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression.

    Christine Chauveau;Séverine Rémy;Pierre Joseph Royer;Marcelo Hill

  • Immune interferon enhances functional properties of human granulocytes: role of Fc receptors and effect of lymphotoxin, tumor necrosis factor, and granulocyte-macrophage colony-stimulating factor.

    B Perussia;M Kobayashi;M E Rossi;I Anegon

  • Fc gamma R(CD16) interaction with ligand induces Ca2+ mobilization and phosphoinositide turnover in human natural killer cells. Role of Ca2+ in Fc gamma R(CD16)-induced transcription and expression of lymphokine genes.

    Marco Antonio Cassatella;I Anegon;Mc Cuturi;P Griskey

  • Preferential proliferation of natural killer cells among peripheral blood mononuclear cells cocultured with B lymphoblastoid cell lines.

    B Perussia;C Ramoni;I Anegon;M C Cuturi

  • Production of hematopoietic colony-stimulating factors by human natural killer cells.

    M C Cuturi;I Anegón;F Sherman;R Loudon

  • CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase.

    Carole Guillonneau;Marcelo Hill;François-Xavier Hubert;Elise Chiffoleau

  • Zinc-finger nucleases: a powerful tool for genetic engineering of animals

    Séverine Rémy;Séverine Rémy;Laurent Tesson;Laurent Tesson;Séverine Ménoret;Séverine Ménoret;Claire Usal;Claire Usal

  • A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance.

    R Josien;P Douillard;C Guillot;M Müschen

  • Effector Mechanisms of Rejection

    Aurélie Moreau;Emilie Varey;Ignacio Anegon;Maria-Cristina Cuturi

  • IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS‐treated dendritic cells

    Marcelo Hill;Marcelo Hill;Séverine Tanguy-Royer;Pierre Royer;Christine Chauveau;Christine Chauveau

  • Overexpression of Transforming Growth Factor-β1 Stabilizes Already-Formed Aortic Aneurysms A First Approach to Induction of Functional Healing by Endovascular Gene Therapy

    Jianping Dai;Franck Losy;Anne-Marie Guinault;Carine Pages

  • Tolerance to Cardiac Allografts Via Local and Systemic Mechanisms After Adenovirus-Mediated CTLA4Ig Expression

    Cécile Guillot;Patrick Mathieu;Hélène Coathalem;Brigitte Le Mauff

  • Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity.

    Séverine Rémy;Philippe Blancou;Laurent Tesson;Virginie Tardif

  • Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.

    Mercedes Segovia;Mercedes Segovia;Sofia Russo;Sofia Russo;Mathias Jeldres;Yamil D. Mahmoud

  • High-Affinity IgG Antibodies Develop Naturally in Ig-Knockout Rats Carrying Germline Human IgH/Igκ/Igλ Loci Bearing the Rat CH Region

    Michael J. Osborn;Biao Ma;Suzanne Avis;Ashleigh Binnie

  • Mechanism and Localization of CD8 Regulatory T Cells in a Heart Transplant Model of Tolerance

    Xian Liang Li;Xian Liang Li;Séverine Ménoret;Séverine Ménoret;Séverine Bezie;Séverine Bezie;Lise Caron;Lise Caron

  • Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection

    Cécile Guillot;Carole Guillonneau;Patrick Mathieu;Christian A. Gerdes

  • Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation

    Julien Rossignol;Cécile Boyer;Cécile Boyer;Reynald Thinard;Séverine Remy

  • Macrophages transfected with adenovirus to express IL-4 reduce inflammation in experimental glomerulonephritis.

    David C. Kluth;Clare V. Ainslie;Wayne P. Pearce;Sian Finlay

Frequent Co-Authors

Jean-Paul Soulillou
Jean-Paul Soulillou University of Nantes
Maria-Cristina Cuturi
Maria-Cristina Cuturi University of Nantes
Régis Josien
Régis Josien Grenoble Alpes University
Alexis M. Kalergis
Alexis M. Kalergis Pontificia Universidad Católica de Chile
Roland Buelow
Roland Buelow MedtechAlert
Philippe Moullier
Philippe Moullier University of Nantes
Giorgio Trinchieri
Giorgio Trinchieri National Institutes of Health
Sophie Brouard
Sophie Brouard University of Nantes
Pedro R. Lowenstein
Pedro R. Lowenstein University of Michigan–Ann Arbor
Bice Perussia
Bice Perussia Kimmel Cancer Center

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