World's Best Scientists 2026 revealed!

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Genetics

D-Index
91
Citations
32705
World Ranking
1030
National Ranking
503

Medicine

D-Index
92
Citations
33786
World Ranking
11240
National Ranking
5770

Overview

Howard J. Jacob is affiliated with AbbVie in the United States and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Economics, Econometrics and Finance. Their work involves intersections between genetics and public health, as well as economic evaluations within health systems.

Their research spans multiple subfields, including Genetics, Public Health, Environmental and Occupational Health, and Economics and Econometrics. This multidisciplinary approach reflects a focus on integrating clinical insights with economic and policy considerations.

Howard J. Jacob's published topics include Genomics and Rare Diseases, Ethics in Clinical Research, and Health Systems, Economic Evaluations, Quality of Life. These highlight an engagement with both the scientific and ethical dimensions of clinical and genomic research, as well as the practical implications for health care quality and economics.

Their recent publication is titled Exploring concordance and discordance for return of incidental findings from clinical sequencing, published in 2020 in UNC Libraries.

  • Robert C. Green
  • Jonathan S. Berg
  • Gerard T. Berry
  • Leslie G. Biesecker
  • David Dimmock

  • UNC Libraries

Best Publications

  • Genome sequence of the Brown Norway rat yields insights into mammalian evolution

    Richard A. Gibbs;George M. Weinstock;Michael L. Metzker;Donna M. Muzny

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

    Aron M. Geurts;Gregory J. Cost;Yevgeniy Freyvert;Bryan Zeitler

  • Characterization of human plasma-derived exosomal RNAs by deep sequencing

    Xiaoyi Huang;Tiezheng Yuan;Michael Tschannen;Zhifu Sun

  • Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.

    Howard J. Jacob;Howard J. Jacob;Klaus Lindpaintner;Klaus Lindpaintner;Stephen E. Lincoln;Kenro Kusumi

  • Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome

    Ahmed H. Kissebah;Gabriele E. Sonnenberg;Joel Myklebust;Michael Goldstein

  • Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease.

    Elizabeth A Worthey;Alan N Mayer;Alan N Mayer;Grant D Syverson;Daniel Helbling

  • The Gene Ontology project in 2008

    Midori A Harris;Jennifer I. Deegan;Amelia Ireland;Jane Lomax

  • A genetic linkage map of the laboratory rat, Rattus norvegicus

    Howard J. Jacob;Howard J. Jacob;Donna M. Brown;Ruth K. Bunker;Mark J. Daly

  • Comparative recombination rates in the rat, mouse, and human genomes.

    Michael I. Jensen-Seaman;Terrence S. Furey;Bret A. Payseur;Yontao Lu

  • A comprehensive linkage analysis for myocardial infarction and its related risk factors.

    Ulrich Broeckel;Christian Hengstenberg;Björn Mayer;Stephan Holmer

  • A microsatellite genetic linkage map for zebrafish (Danio rerio).

    Ela W. Knapik;Alec Goodman;Marc Ekker;Mario Chevrette

  • Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

    Joon Won Yoon;Yasuhiro Kita;Daniel J. Frank;Rebecca R. Majewski

  • The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome.

    Anthony G. Comuzzie;Tohru Funahashi;Gabriele Sonnenberg;Lisa J. Martin

  • Zebrafish genetic map with 2000 microsatellite markers.

    N. Shimoda;E. W. Knapik;J. Ziniti;Chäng Sim

  • Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat.

    Joakim Galli;Luo-Sheng Li;Anna Glaser;Claes-Göran Östenson

  • Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat.

    Donna M. Brown;Abraham P. Provoost;Mark J. Daly;Eric S. Lander

  • Progress and prospects in rat genetics: a community view.

    Timothy J Aitman;John K Critser;Edwin Cuppen;Anna Dominiczak

  • Rat genetics: attaching physiology and pharmacology to the genome.

    Howard J Jacob;Anne E Kwitek

  • Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

    Kimberly Splinter;David R. Adams;Carlos A. Bacino;Hugo J. Bellen

Frequent Co-Authors

Richard J. Roman
Richard J. Roman University of Mississippi Medical Center
Aron M. Geurts
Aron M. Geurts Medical College of Wisconsin
Allen W. Cowley
Allen W. Cowley Medical College of Wisconsin
Anne E. Kwitek
Anne E. Kwitek Medical College of Wisconsin
Eric S. Lander
Eric S. Lander Broad Institute
Mingyu Liang
Mingyu Liang Medical College of Wisconsin
Claude Szpirer
Claude Szpirer Université Libre de Bruxelles
Victor J. Dzau
Victor J. Dzau Duke University
Åke Lernmark
Åke Lernmark Lund University
Michal Pravenec
Michal Pravenec Czech Academy of Sciences

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