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Roland Buelow

Roland Buelow

D-Index & Metrics

Immunology

D-Index
50
Citations
9174
World Ranking
4249
National Ranking
1936

Overview

Roland Buelow is affiliated with MedtechAlert in the United States and has contributed research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Radiology, Nuclear Medicine and Imaging, Oncology, Immunology, Physiology, and Biotechnology.

The main topics of Roland Buelow's research include:

  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research
  • Calcium signaling and nucleotide metabolism
  • Cancer Research and Treatments
  • Immunotherapy and Immune Responses
  • Radiopharmaceutical Chemistry and Applications
  • Lymphoma Diagnosis and Treatment

Roland Buelow has published in several scientific journals, with frequent appearances in:

  • mAbs
  • Journal for ImmunoTherapy of Cancer
  • Scientific Reports
  • OncoImmunology
  • Cancer Research

Frequent co-authors in their publications include:

  • Suhasini Iyer
  • Ute Schellenberger
  • Laura Davison
  • Harshad S. Ugamraj
  • Andrew Boudreau

Notable recent publications by Roland Buelow feature studies related to bispecific antibodies and tumor cell cytotoxicity, including:

  • "Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release", 2021, Journal for ImmunoTherapy of Cancer
  • "TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL", 2021, mAbs
  • "A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells", 2021, Scientific Reports
  • "TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity", 2022, mAbs
  • "A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer", 2022, OncoImmunology

Best Publications

  • Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

    Aron M. Geurts;Gregory J. Cost;Yevgeniy Freyvert;Bryan Zeitler

  • Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury.

    Farin Amersi;Roland Buelow;Hirohisa Kato;Bibo Ke

  • Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes.

    Wayne W. Hancock;Roland Buelow;Mohamed H. Sayegh;Laurence A. Turka

  • Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway.

    Farin Amersi;Xiu-Da Shen;Dean Anselmo;Judy Melinek

  • Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway.

    Masamichi Katori;Roland Buelow;Bibo Ke;Jeff Ma

  • Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1.

    Stefan G. Tullius;Melina Nieminen-Kelhä;Roland Buelow;Anja Reutzel-Selke

  • Heme oxygenase-1 overexpression protects rat livers from ischemia/reperfusion injury with extended cold preservation.

    Hirohisa Kato;Farin Amersi;Roland Buelow;Judy Melinek

  • Production of humanized antibodies in transgenic animals

    Jens-Ulrich Buelow;Roland Buelow;Josef Platzer;Wim-Van Schooten

  • Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury.

    Ana J Coito;Roland Buelow;Xiu-Da Shen;Farin Amersi

  • Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.

    Bibo Ke;Roland Buelow;Xiu-Da Shen;Judy Melinek

  • Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury.

    Tom D. Blydt-Hansen;Masamichi Katori;Charles Lassman;Bibo Ke

  • Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32)

    Jacky Woo;Suhasini Iyer;Marie-Christine Cornejo;Nancy Mori

  • Human Antibody Production in Transgenic Animals

    Marianne Brüggemann;Michael J. Osborn;Biao Ma;Jasvinder Hayre

  • Computer-assisted rational design of immunosuppressive compounds.

    Gérard Grassy;Bernard Calas;Abdelaziz Yasri;Roger Lahana

  • High-Affinity IgG Antibodies Develop Naturally in Ig-Knockout Rats Carrying Germline Human IgH/Igκ/Igλ Loci Bearing the Rat CH Region

    Michael J. Osborn;Biao Ma;Suzanne Avis;Ashleigh Binnie

  • Induction of long-term cardiac allograft survival by heme oxygenase-1 gene transfer.

    C Braudeau;D Bouchet;L Tesson;S Iyer

  • A chemical basis for selective recognition of nonpeptide antigens by human delta T cells.

    Christian Belmant;Eric Espinosa;Franck Halary;Yong Tang

  • Systemic Rather Than Local Heme Oxygenase-1 Overexpression Improves Cardiac Allograft Outcomes in a New Transgenic Mouse

    Jesus A. Araujo;Lingzhong Meng;Aaron D. Tward;Wayne W. Hancock

  • Antigen-specific (p30) mouse CD8+ T cells are cytotoxic against Toxoplasma gondii-infected peritoneal macrophages

    L H Kasper;I A Khan;K H Ely;R Buelow

  • Correlation of ELISA-detected IgG and IgA anti-HLA antibodies in pretransplant sera with renal allograft rejection

    Ronald H. Kerman;Brian Susskind;Roland Buelow;Jeffrey Regan

  • Topical application of a novel immunomodulatory peptide, RDP58, reduces skin inflammation in the phorbol ester-induced dermatitis model.

    Christopher G. De Vry;Marybeth Valdez;Mirella Lazarov;Evelyn Muhr

  • Immunomodulation by soluble HLA class I.

    Roland Buelow;William J. Burlingham;Carol Clayberger

  • Identification of patients at high risk of graft loss by pre- and posttransplant monitoring of anti-HLA class I IgG antibodies by enzyme-linked immunosorbent assay.

    Francisco Monteiro;Roland Buelow;Carlos Mineiro;Helcio Rodrigues

Frequent Co-Authors

Jerzy W. Kupiec-Weglinski
Jerzy W. Kupiec-Weglinski University of California, Los Angeles
Ignacio Anegon
Ignacio Anegon University of Nantes
Hans-Dieter Volk
Hans-Dieter Volk Charité - University Medicine Berlin
Ronald W. Busuttil
Ronald W. Busuttil University of California, Los Angeles
Jean-Paul Soulillou
Jean-Paul Soulillou University of Nantes
Mohamed H. Sayegh
Mohamed H. Sayegh American University of Beirut
Maria-Cristina Cuturi
Maria-Cristina Cuturi University of Nantes
Stefan G. Tullius
Stefan G. Tullius Brigham and Women's Hospital
Peter Neuhaus
Peter Neuhaus Charité - University Medicine Berlin
Wayne W. Hancock
Wayne W. Hancock University of Pennsylvania

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