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Immunology

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66
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Overview

Alexis M. Kalergis is affiliated with Pontificia Universidad Católica de Chile in Chile. Their research primarily focuses on medicine, with a strong emphasis on infectious diseases, epidemiology, immunology, molecular biology, and health. Their work encompasses a broad range of topics related to respiratory viral infections and immune responses.

The main topics of Alexis M. Kalergis's research include:

  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Vaccine Coverage and Hesitancy
  • Neonatal Respiratory Health Research
  • Immune Cell Function and Interaction
  • Immune responses and vaccinations

They have contributed to 283 publications in the field of medicine, with notable subfields being infectious diseases (90 publications), epidemiology (74 publications), and immunology (61 publications). Their research outputs are frequently published in venues such as:

  • Frontiers in Immunology (31 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (9 publications)
  • Vaccines (9 publications)
  • International Journal of Molecular Sciences (7 publications)
  • Frontiers in Endocrinology (6 publications)

Among their recent papers are:

  • "Naturally Derived Heme-Oxygenase 1 Inducers and Their Therapeutic Application to Immune-Mediated Diseases," 2020, Frontiers in Immunology
  • "Could BCG Vaccination Induce Protective Trained Immunity for SARS-CoV-2?" 2020, Frontiers in Immunology
  • "Safety and Immunogenicity of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Subgroup of Healthy Adults in Chile," 2021, Clinical Infectious Diseases
  • "Respiratory Syncytial Virus Vaccines: A Review of the Candidates and the Approved Vaccines," 2023, Pathogens
  • "The Role of Dendritic Cells During Infections Caused by Highly Prevalent Viruses," 2020, Frontiers in Immunology

Collaboration is a significant aspect of their research, often working closely with frequent co-authors including Susan M. Bueno, Pablo A. González, Jorge A. Soto, Claudia A. Riedel, and Nicolás M. S. Gálvez.

Best Publications

  • Implications of macrophage polarization in autoimmunity.

    Samanta C. Funes;Mariana Rios;Jorge Escobar-Vera;Alexis M. Kalergis

  • Neurologic Alterations Due to Respiratory Virus Infections

    Karen Bohmwald;Nicolás M. S. Gálvez;Mariana Ríos;Alexis M. Kalergis

  • Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells

    Alexis M. Kalergis;Jeffrey V. Ravetch

  • Innate Immunity and Inflammation in NAFLD/NASH.

    Marco Arrese;Daniel Cabrera;Alexis M. Kalergis;Ariel E. Feldstein;Ariel E. Feldstein

  • Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

    Alexis M. Kalergis;Nicole Boucheron;Marie-Agnés Doucey;Edith Palmieri

  • BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design

    Camila Covián;Camila Covián;Ayleen Fernández-Fierro;Angello Retamal-Díaz;Fabián E. Díaz

  • Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension

    Natalia Muñoz-Durango;Cristóbal A. Fuentes;Andrés E. Castillo;Luis Martín González-Gómez

  • Andrographolide interferes with T cell activation and reduces experimental autoimmune encephalomyelitis in the mouse.

    Mirentxu I Iruretagoyena;Jaime A Tobar;Pablo A González;Sofía E Sepúlveda

  • Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes

    Cristián A. Amador;Víctor Barrientos;Juan Peña;Andrés A. Herrada

  • Intestinal microbiota influences non-intestinal related autoimmune diseases

    Maria C. Opazo;Elizabeth M. Ortega-Rocha;Irenice Coronado-Arrázola;Laura C. Bonifaz

  • Endothelial-to-mesenchymal transition: Cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions.

    Lorena Pérez;Lorena Pérez;Natalia Muñoz-Durango;Claudia A. Riedel;Claudia A. Riedel;Cesar Echeverría

  • Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity

    Andrés A. Herrada;Francisco J. Contreras;Natacha P. Marini;Cristian A. Amador

  • T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.

    Pablo A. González;Leandro J. Carreño;Daniel Coombs;Jorge E. Mora

  • Activated TCRs remain marked for internalization after dissociation from pMHC.

    Daniel Coombs;Alexis M. Kalergis;Stanley G. Nathenson;Carla Wofsy;Carla Wofsy

  • Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells

    Pablo A. González;Carolina E. Prado;Eduardo D. Leiva;Leandro J. Carreño

  • Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG

    Susan M. Bueno;Pablo A. González;Kelly M. Cautivo;Jorge E. Mora

  • Salmonella Escape from Antigen Presentation Can Be Overcome by Targeting Bacteria to Fcγ Receptors on Dendritic Cells

    Jaime A. Tobar;Pablo A. González;Alexis M. Kalergis

  • Virulent salmonella enterica serovar typhimurium evades adaptive immunity by preventing dendritic cells from activating t cells

    Jaime A. Tobar;Leandro J. Carreño;Susan M. Bueno;Pablo A. González

  • Inhibition of Nuclear Factor-κB Enhances the Capacity of Immature Dendritic Cells to Induce Antigen-Specific Tolerance in Experimental Autoimmune Encephalomyelitis

    Mirentxu I. Iruretagoyena;Sofía E. Sepúlveda;J. Pablo Lezana;Marcela Hermoso

  • Interplay between thermal and immune ecology: effect of environmental temperature on insect immune response and energetic costs after an immune challenge.

    Tamara P. Catalán;Aniela Wozniak;Hermann M. Niemeyer;Alexis M. Kalergis

  • Host immunity during RSV pathogenesis

    Susan M. Bueno;Pablo A. Gonzalez;Rodrigo Pacheco;Eduar Do D. Leiva

Frequent Co-Authors

Susan M. Bueno
Susan M. Bueno Pontificia Universidad Católica de Chile
Stanley G. Nathenson
Stanley G. Nathenson Albert Einstein College of Medicine
Ignacio Anegon
Ignacio Anegon University of Nantes
Francisco Bozinovic
Francisco Bozinovic Pontificia Universidad Católica de Chile
Eliseo A. Eugenin
Eliseo A. Eugenin The University of Texas Medical Branch at Galveston
Pablo Sabat
Pablo Sabat University of Chile
John F. DiPersio
John F. DiPersio Washington University in St. Louis
Juan Carlos Roa
Juan Carlos Roa University of Córdoba
Hermann M. Niemeyer
Hermann M. Niemeyer University of Chile
Michael L. Dustin
Michael L. Dustin University of Oxford

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