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Immunology

D-Index
50
Citations
6948
World Ranking
4285
National Ranking
2

Overview

Julio Villena is affiliated with the National Scientific and Technical Research Council in Argentina. Their research primarily focuses on fields such as Medicine, Agricultural and Biological Sciences, and Biochemistry, Genetics and Molecular Biology. The subfields they contribute to include Food Science, Infectious Diseases, Molecular Biology, Epidemiology, and Immunology.

The main topics of Villena's work encompass:

  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Viral gastroenteritis research and epidemiology
  • Immune Response and Inflammation
  • Pediatric health and respiratory diseases
  • Respiratory viral infections research
  • Clostridium difficile and Clostridium perfringens research

Villena has published extensively in several prominent scientific journals. Frequent publication venues include:

  • Microorganisms
  • International Journal of Molecular Sciences
  • Frontiers in Microbiology
  • Frontiers in Immunology
  • Pathogens

Recent papers authored by Julio Villena include:

  • "The Modulation of Mucosal Antiviral Immunity by Immunobiotics: Could They Offer Any Benefit in the SARS-CoV-2 Pandemic?" (2020), Frontiers in Physiology
  • "Immunomodulation Potential of Probiotics: A Novel Strategy for Improving Livestock Health, Immunity, and Productivity" (2022), Microorganisms
  • "Lipoteichoic Acid Is Involved in the Ability of the Immunobiotic Strain Lactobacillus plantarum CRL1506 to Modulate the Intestinal Antiviral Innate Immunity Triggered by TLR3 Activation" (2020), Frontiers in Immunology
  • "The Ability of Respiratory Commensal Bacteria to Beneficially Modulate the Lung Innate Immune Response Is a Strain Dependent Characteristic" (2020), Microorganisms
  • "Immunomodulatory Effects of Probiotics: A Novel Preventive Approach for the Control of Bovine Mastitis" (2022), Microorganisms

Collaborative work is a significant part of Villena's research. Frequently collaborating coauthors include:

  • Haruki Kitazawa
  • Leonardo Albarracín
  • Kohtaro Fukuyama
  • Md. Aminul Islam
  • Mikado Tomokiyo

Best Publications

  • Immunobiotic Lactobacillus jensenii Elicits Anti-Inflammatory Activity in Porcine Intestinal Epithelial Cells by Modulating Negative Regulators of the Toll-Like Receptor Signaling Pathway

    Tomoyuki Shimazu;Julio Cesar Villena;Masanori Tohno;Hitomi Fujie

  • Nasally administered Lactobacillus rhamnosus strains differentially modulate respiratory antiviral immune responses and induce protection against respiratory syncytial virus infection

    Yohsuke Tomosada;Eriko Chiba;Hortensia Zelaya;Takuya Takahashi

  • Immunomodulatory activity of Lactobacillus rhamnosus strains isolated from goat milk: impact on intestinal and respiratory infections.

    Susana Salva;Julio Villena;Susana Alvarez;Susana Alvarez

  • Modulation of Intestinal TLR4-Inflammatory Signaling Pathways by Probiotic Microorganisms: Lessons Learned from Lactobacillus jensenii TL2937

    Julio Cesar Villena;Haruki Kitazawa

  • Immunoregulatory Effect of Bifidobacteria Strains in Porcine Intestinal Epithelial Cells through Modulation of Ubiquitin-Editing Enzyme A20 Expression

    Yohsuke Tomosada;Julio Villena;Julio Villena;Kozue Murata;Eriko Chiba

  • Respiratory Commensal Bacteria Corynebacterium pseudodiphtheriticum Improves Resistance of Infant Mice to Respiratory Syncytial Virus and Streptococcus pneumoniae Superinfection.

    Paulraj Kanmani;Patricia Clua;Maria G. Vizoso-Pinto;Cecilia Rodriguez

  • Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells.

    Jonathan Laiño;Julio Villena;Julio Villena;Paulraj Kanmani;Haruki Kitazawa

  • Orally administered Lactobacillus rhamnosus modulates the respiratory immune response triggered by the viral pathogen-associated molecular pattern poly(I:C)

    Julio Villena;Julio Villena;Eriko Chiba;Yohsuke Tomosada;Susana Salva

  • Lactobacillus casei Improves Resistance to Pneumococcal Respiratory Infection in Malnourished Mice

    Julio Villena;Silvia Racedo;Graciela Agüero;Elena Bru

  • The toll-like receptor family protein RP105/MD1 complex is involved in the immunoregulatory effect of exopolysaccharides from Lactobacillus plantarum N14.

    Yo Murofushi;Julio Cesar Villena;Julio Cesar Villena;Kyoko Morie;Paulraj Kanmani

  • Respiratory antiviral immunity and immunobiotics: Beneficial effects on inflammation-coagulation interaction during influenza virus infection

    Hortensia Zelaya;Susana Alvarez;Haruki Kitazawa;Julio Villena

  • Lactobacillus casei administration reduces lung injuries in a Streptococcus pneumoniae infection in mice

    Silvia Racedo;Julio Villena;Julio Villena;Marcela Medina;Marcela Medina;Graciela Agüero

  • Exopolysaccharides from Lactobacillus delbrueckii OLL1073R-1 modulate innate antiviral immune response in porcine intestinal epithelial cells

    Paulraj Kanmani;Leonardo Albarracin;Hisakazu Kobayashi;Hikaru Iida

  • Immunobiotic Lactobacillus jensenii Modulates the Toll-Like Receptor 4-Induced Inflammatory Response via Negative Regulation in Porcine Antigen-Presenting Cells

    Julio Villena;Rie Suzuki;Hitomi Fujie;Eriko Chiba

  • Lactobacillus delbrueckii TUA4408L and its extracellular polysaccharides attenuate enterotoxigenic Escherichia coli-induced inflammatory response in porcine intestinal epitheliocytes via Toll-like receptor-2 and 4.

    Satoshi Wachi;Paulraj Kanmani;Yohsuke Tomosada;Hisakazu Kobayashi

  • Immunobiotic Lactobacillus rhamnosus improves resistance of infant mice against respiratory syncytial virus infection

    Eriko Chiba;Yohsuke Tomosada;Maria Guadalupe Vizoso-Pinto;Susana Salva

  • Intestinal Innate Antiviral Immunity and Immunobiotics: Beneficial Effects against Rotavirus Infection.

    Julio Villena;Maria Guadalupe Vizoso-Pinto;Haruki Kitazawa

  • Development of a fermented goats' milk containing Lactobacillus rhamnosus: in vivo study of health benefits

    Susana Salva;Martha Nuñez;Julio Villena;Adriana Ramón

  • Immunobiotic Bifidobacteria Strains Modulate Rotavirus Immune Response in Porcine Intestinal Epitheliocytes via Pattern Recognition Receptor Signaling.

    Takamasa Ishizuka;Paulraj Kanmani;Hisakazu Kobayashi;Ayako Miyazaki

  • Stimulation of macrophages by immunobiotic Lactobacillus strains: influence beyond the intestinal tract

    Gabriela Marranzino;Julio Villena;Susana Salva;Susana Alvarez

  • Lactic acid bacteria in the prevention of pneumococcal respiratory infection: future opportunities and challenges.

    Julio Villena;Maria Leonor S. Oliveira;Patricia C.D. Ferreira;Susana Salva

Frequent Co-Authors

Haruki Kitazawa
Haruki Kitazawa Tohoku University
Susana Alvarez
Susana Alvarez National Scientific and Technical Research Council
Hideki Takahashi
Hideki Takahashi Tohoku University
Tadao Saito
Tadao Saito Tohoku University
Tomonori Nochi
Tomonori Nochi Tohoku University
Victor P.M.G. Rutten
Victor P.M.G. Rutten University of Pretoria
Andrey V. Karlyshev
Andrey V. Karlyshev Kingston University
Willem van Eden
Willem van Eden Utrecht University
Borja Sánchez
Borja Sánchez Spanish National Research Council
Philippe Langella
Philippe Langella University of Paris-Saclay

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