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Tadao Saito

Tadao Saito

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
10314
World Ranking
11050
National Ranking
761

Overview

Tadao Saito is a researcher affiliated with Tohoku University in Japan, specializing in the field of Biochemistry, Genetics and Molecular Biology. Their work largely focuses on Molecular Biology, Aging, Cell Biology, and Genetics, with numerous contributions touching on the dynamics of genetics, aging processes, and cellular mechanisms at the molecular level.

Their recent publications highlight investigations into meiotic chromosome dynamics, genetic crossover frequency, and DNA repair mechanisms, often using Caenorhabditis elegans as a model organism. Key research articles include:

  • "HIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis" (2021, Proceedings of the National Academy of Sciences)
  • "GRAS-1 is a conserved novel regulator of early meiotic chromosome dynamics in C. elegans" (2022, bioRxiv (Cold Spring Harbor Laboratory))
  • "GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans" (2023, PLoS Genetics)
  • "Caenorhabditis elegans brc-1 mutation increases the number of COSA-1 foci in him-8 and zim-2 mutants" (2023, PubMed)
  • "Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR" (2025, Journal of Visualized Experiments)

Their collaborative efforts frequently involve close partnerships with researchers such as Saravanapriah Nadarajan, Marina Martínez-García, Mónica P. Colaiácovo, Pedro Robles Naharro, and Marnie W. Skinner. These collaborations have contributed across multiple studies and publications.

Tadao Saito's work is disseminated through multiple reputable scientific venues, including:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Genetics
  • PubMed
  • Journal of Visualized Experiments

The main research topics covered in their studies encompass:

  • Genetics, Aging, and Longevity in Model Organisms
  • DNA Repair Mechanisms
  • Microtubule and mitosis dynamics
  • Mitochondrial Function and Pathology
  • Evolution and Genetic Dynamics
  • Photosynthetic Processes and Mechanisms

This range of topics indicates a broad approach to understanding biological systems, particularly related to genetic behavior during meiosis, cellular aging, and the mechanisms underpinning cellular structure and function. Their contributions form part of ongoing efforts to elucidate the molecular underpinnings of aging and genetic regulation using model organisms.

Best Publications

  • Structural Analysis of New Antihypertensive Peptides Derived from Cheese Whey Protein by Proteinase K Digestion

    Amhar Abubakar;Tadao Saito;Haruki Kitazawa;Yasushi Kawai

  • Isolation and structural analysis of antihypertensive peptides that exist naturally in Gouda cheese.

    Tadao Saito;T. Nakamura;Haruki Kitazawa;Yasushi Kawai

  • Oligosaccharides of milk and colostrum in non-human mammals.

    Tadasu Urashima;Tadao Saito;Tadashi Nakamura;Michael Messer

  • Cell surface Lactobacillus plantarum LA 318 glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) adheres to human colonic mucin

    H. Kinoshita;H. Uchida;Y. Kawai;T. Kawasaki

  • Immunobiotic Lactobacillus jensenii Elicits Anti-Inflammatory Activity in Porcine Intestinal Epithelial Cells by Modulating Negative Regulators of the Toll-Like Receptor Signaling Pathway

    Tomoyuki Shimazu;Julio Cesar Villena;Masanori Tohno;Hitomi Fujie

  • Immunomodulatory Effects of Polysaccharides Produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1

    S. Makino;S. Ikegami;H. Kano;T. Sashihara

  • Variations and Distributions of O-Glycosidically Linked Sugar Chains in Bovine κ-Casein

    Tadao Saito;Takatoshi Itoh

  • Biosorption of heavy metals by lactic acid bacteria and identification of mercury binding protein

    Hideki Kinoshita;Yui Sohma;Fumika Ohtake;Mitsuharu Ishida

  • Antihypertensive Peptides Derived from Bovine Casein and Whey Proteins

    Tadao Saito

  • Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line.

    Masayuki Moue;Masanori Tohno;Tomoyuki Shimazu;Taketomo Kido

  • Structural analysis of a new anti-hypertensive peptide (β-lactosin B) isolated from a commercial whey product

    M. Murakami;H. Tonouchi;R. Takahashi;H. Kitazawa

  • Inhibition of food‐borne pathogenic bacteria by bacteriocins from Lactobacillus gasseri

    T. Itoh;Y. Fujimoto;Y. Kawai;T. Toba

  • Immunoregulatory Effect of Bifidobacteria Strains in Porcine Intestinal Epithelial Cells through Modulation of Ubiquitin-Editing Enzyme A20 Expression

    Yohsuke Tomosada;Julio Villena;Julio Villena;Kozue Murata;Eriko Chiba

  • Gassericin A; an Uncommon Cyclic Bacteriocin Produced by Lactobacillus gasseri LA39 Linked at N- and C-Terminal Ends

    Yasushi Kawai;Tadao Saito;Haruki Kitazawa;Takatoshi Itoh

  • Structural and functional differences in two cyclic bacteriocins with the same sequences produced by lactobacilli.

    Yasushi Kawai;Yasuyuki Ishii;Kensuke Arakawa;Koichiro Uemura

  • The Circular Bacteriocins Gassericin A and Circularin A

    Yasushi Kawai;Rober Kemperman;Jan Kok;Tadao Saito

  • The toll-like receptor family protein RP105/MD1 complex is involved in the immunoregulatory effect of exopolysaccharides from Lactobacillus plantarum N14.

    Yo Murofushi;Julio Cesar Villena;Julio Cesar Villena;Kyoko Morie;Paulraj Kanmani

  • Functional alteration of murine macrophages stimulated with extracellular polysaccharides from Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1

    Junko Nishimura-Uemura;Haruki Kitazawa;Yasushi Kawai;Takatoshi Itoh

  • Strong immunostimulation in murine immune cells by Lactobacillus rhamnosus GG DNA containing novel oligodeoxynucleotide pattern

    Iliyan D. Iliev;Haruki Kitazawa;Takeshi Shimosato;Shinichiro Katoh

  • Determination of each neutral oligosaccharide in the milk of Japanese women during the course of lactation

    Wataru Sumiyoshi;Tadasu Urashima;Tadashi Nakamura;Ikichi Arai

Frequent Co-Authors

Haruki Kitazawa
Haruki Kitazawa Tohoku University
Julio Villena
Julio Villena National Scientific and Technical Research Council
Olav T. Oftedal
Olav T. Oftedal Smithsonian Environmental Research Center
Akira Horii
Akira Horii Tohoku University
Yukiko Yamazaki
Yukiko Yamazaki University of Hawaii at Manoa
Tomonori Nochi
Tomonori Nochi Tohoku University
Christian Lydersen
Christian Lydersen Norwegian Polar Institute
Jan Kok
Jan Kok University of Groningen
Susana Alvarez
Susana Alvarez National Scientific and Technical Research Council
Ji Ming Wang
Ji Ming Wang National Institutes of Health

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