What is he best known for?
The fields of study he is best known for:
Akira Horii mainly investigates Cancer research, Molecular biology, Familial adenomatous polyposis, Carcinogenesis and Genetics.
His Cancer research research includes themes of Pancreatic cancer, Somatic cell, Pancreas, Pathology and Frameshift mutation.
His study in Molecular biology is interdisciplinary in nature, drawing from both Intestinal mucosa, Gene expression, DNA methylation, Exon and Adenocarcinoma.
The study incorporates disciplines such as Gene duplication, Gene, Tumor suppressor gene and Adenomatous polyposis coli in addition to Familial adenomatous polyposis.
His research in Adenomatous polyposis coli intersects with topics in Mutation, Point mutation, Nonsense mutation and Germline.
His work in the fields of Genetics, such as Adenoma and Sequence-tagged site, intersects with other areas such as Human genome, Bacterial artificial chromosome and Contig Mapping.
His most cited work include:
- Identification of FAP locus genes from chromosome 5q21 (2021 citations)
- Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients (1627 citations)
- Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene (840 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Cancer research, Molecular biology, Gene, Genetics and Pancreatic cancer.
His Cancer research research includes elements of Carcinogenesis, Cancer, Tumor suppressor gene, Pathology and Loss of heterozygosity.
Akira Horii usually deals with Molecular biology and limits it to topics linked to DNA methylation and Methylation.
His Gene research incorporates themes from Adenomatous polyposis coli and Familial adenomatous polyposis.
His Adenomatous polyposis coli study combines topics in areas such as Germline and Point mutation.
His work on Chromosome, Endometrial cancer, Allele and DNA mismatch repair as part of general Genetics study is frequently connected to Bacterial artificial chromosome, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
He most often published in these fields:
- Cancer research (46.95%)
- Molecular biology (29.75%)
- Gene (26.52%)
What were the highlights of his more recent work (between 2010-2021)?
- Cancer research (46.95%)
- Cancer (17.92%)
- Epigenetics (6.81%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cancer research, Cancer, Epigenetics, DNA methylation and Pancreatic cancer.
His research integrates issues of Gene knockdown, Head and neck squamous-cell carcinoma, Downregulation and upregulation, Metastasis and Lung cancer in his study of Cancer research.
His Cancer study incorporates themes from Oncology and Pathology.
His biological study spans a wide range of topics, including Molecular biology, Histone and Genetic testing.
His studies deal with areas such as Cell culture and Perineural invasion as well as Pancreatic cancer.
He is investigating Demethylating agent as part of his Genetics and Gene and Demethylating agent study.
Between 2010 and 2021, his most popular works were:
- Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers (97 citations)
- DNA methylation in cancer: a gene silencing mechanism and the clinical potential of its biomarkers (61 citations)
- DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells. (60 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cancer research, Pancreatic cancer, Epigenetics, DNA methylation and Carcinogenesis.
His Cancer research research integrates issues from Biomarker, Jurkat cells and Pancreatic ductal adenocarcinoma.
The concepts of his Pancreatic cancer study are interwoven with issues in Cell culture, Molecular pathology and Metastasis.
Akira Horii has researched DNA methylation in several fields, including Cancer and Histone.
The study of Gene and Genetics are components of his Demethylating agent research.
Gene is closely attributed to Molecular biology in his research.
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