World's Best Scientists 2026 revealed!
Akira Horii

Akira Horii

D-Index & Metrics

Molecular Biology

D-Index
72
Citations
23010
World Ranking
1310
National Ranking
106

Overview

Akira Horii is affiliated with Tohoku University in Japan and has contributed extensively to research in medicine and biochemistry. Their work spans several fields with a focus on molecular biology, oncology, and pulmonary and respiratory medicine.

The scientist's recent publications include studies in various journals, demonstrating engagement with topics such as vascular remodeling, chemoresistance in tumors, and gene regulation in cancer. Notable recent papers are:

  • Progression of vascular remodeling in pulmonary vein obstruction, 2020, Journal of Thoracic and Cardiovascular Surgery
  • Attempts to remodel the pathways of gemcitabine metabolism: Recent approaches to overcoming tumours with acquired chemoresistance, 2020, Cancer Drug Resistance
  • Genetic and epigenetic aberrations of ABCB1 synergistically boost the acquisition of taxane resistance in esophageal squamous cancer cells, 2020, Biochemical and Biophysical Research Communications
  • Methylation-mediated silencing of the LIM homeobox 6 (LHX6) gene promotes cell proliferation in human pancreatic cancer, 2020, Biochemical and Biophysical Research Communications
  • Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancer, 2020, Cancer Science

Frequent coauthors collaborating with Akira Horii include:

  • Yuriko Saiki
  • Shinichi Fukushige
  • Shuto Hirota
  • Fuyuhiko Motoi
  • Michiaki Unno

Their publications often appear in journals such as:

  • Cancer Science
  • Biochemical and Biophysical Research Communications
  • Clinical Case Reports
  • ChemMedChem
  • Journal of Thoracic and Cardiovascular Surgery

Akira Horii's primary fields of study are Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, their research focuses on subfields including:

  • Molecular Biology
  • Oncology
  • Pulmonary and Respiratory Medicine
  • Neurology
  • Cancer Research

The main topics covered by Horii's research reflect a strong emphasis on cancer and molecular mechanisms, including:

  • Epigenetics and DNA Methylation
  • Pancreatic and Hepatic Oncology Research
  • Cancer-related gene regulation
  • Biochemical and Molecular Research
  • Prostate Cancer Treatment and Research
  • Cancer Immunotherapy and Biomarkers
  • Neuroblastoma Research and Treatments

Best Publications

  • Identification of FAP locus genes from chromosome 5q21

    Kenneth W. Kinzler;Mef C. Nilbert;Li Kuo Su;Bert Vogelstein

  • Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

    Isamu Nishisho;Yusuke Nakamura;Yasuo Miyoshi;Yoshio Miki

  • Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

    Yasuo Mori;Hiroki Nagse;Hiroshi Ando;Akira Horii

  • Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study.

    Toru Furukawa;Günter Klöppel;N. Volkan Adsay;Jorge Albores-Saavedra

  • Disruption of the APC Gene by a Retrotransposal Insertion of L1 Sequence in a Colon Cancer

    Yoshio Miki;Isamu Nishisho;Isamu Nishisho;Isamu Nishisho;Akira Horii;Yasuo Miyoshi

  • Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

    Yasuo Miyoshi;Hiroshi Ando;Hiroki Nagase;Isamu Nishisho

  • Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

    Hiroki Nagase;Hiroki Nagase;Yasuo Miyoshi;Akira Horii;Takahisa Aoki

  • PTEN1 is frequently mutated in primary endometrial carcinomas

    Dehe Kong;Dehe Kong;Akihiko Suzuki;Tong Tong Zou;Akira Sakurada;Akira Sakurada

  • Frequent Replication Errors at Microsatellite Loci in Tumors of Patients with Multiple Primary Cancers

    Akira Horii;Hye-Jung Han;Mamoru Shimada;Akio Yanagisawa

  • Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

    Shuichi Nakatsuru;Akio Yanagisawa;Shigetoshi Ichii;Eiichi Tahara

  • The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.

    Akira Horii;Shuichi Nakatsuru;Yasuo Miyoshi;Shigetoshi Ichii

  • RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

    Tatsuo Hata;Toru Furukawa;Makoto Sunamura;Shinichi Egawa

  • Frequent Somatic Mutations of the APC Gene in Human Pancreatic Cancer

    Akira Horii;Shuichi Nakatsuru;Yasuo Miyoshi;Shigetoshi Ichii

  • Potential Tumor Suppressive Pathway Involving DUSP6/MKP-3 in Pancreatic Cancer

    Toru Furukawa;Makoto Sunamura;Fuyuhiko Motoi;Seiki Matsuno

  • Cell surface Lactobacillus plantarum LA 318 glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) adheres to human colonic mucin

    H. Kinoshita;H. Uchida;Y. Kawai;T. Kawasaki

  • The H-cadherin (CDH13) gene is inactivated in human lung cancer.

    Masami Sato;Yuriko Mori;Akira Sakurada;Shigefumi Fujimura

  • The Insulin-like Growth Factor II Receptor Gene Is Mutated in Genetically Unstable Cancers of the Endometrium, Stomach, and Colorectum

    Hong Ouyang;Hiromi O. Shiwaku;Hisashi Hagiwara;Ko Miura

  • A Novel Target Gene, SKP2, within the 5p13 Amplicon That Is Frequently Detected in Small Cell Lung Cancers

    Sana Yokoi;Kohichiroh Yasui;Fumiko Saito-Ohara;Katsumi Koshikawa

  • Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP)

    Ichii S;Takeda S;Horii A;Nakatsuru S

  • Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP)

    Shigetoshi Ichii;Akira Horii;Shuichi Nakatsuru;Junichi Furuyama

Frequent Co-Authors

Yusuke Nakamura
Yusuke Nakamura National Institutes of Biomedical Innovation, Health and Nutrition
Seiki Matsuno
Seiki Matsuno Tohoku University
Michiaki Unno
Michiaki Unno Tohoku University
Kenichi Matsubara
Kenichi Matsubara Osaka University
Haruki Kitazawa
Haruki Kitazawa Tohoku University
Johji Inazawa
Johji Inazawa Tokyo Medical and Dental University
Tadao Saito
Tadao Saito Tohoku University
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Hironobu Sasano
Hironobu Sasano Tohoku University
Dan G. Duda
Dan G. Duda Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're passionate about molecular biology but interested in flexible learning or alternative healthcare pathways, many online degree options are available. Students already working in healthcare can find accelerated bridge programs, like the fastest rn to bsn program online, which help registered nurses earn their Bachelor of Science in Nursing quickly. For those with an associate degree, programs like the asn to np pathway offer a streamlined route from ADN to Nurse Practitioner roles.

Individuals from non-nursing backgrounds considering a career shift may explore direct entry msn programs online, which allow those without a nursing degree to enter the nursing profession at an advanced level. When evaluating schools, especially for online nursing programs, it’s essential to research accreditation. For example, read about capella university nursing accreditation to ensure your chosen program meets high educational standards.

Exploring these online options can open doors to diverse careers in healthcare, research, and education, often complementing a foundation in molecular biology.

Best Scientists Citing Akira Horii

Trending Scientists

Recently Published Articles