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Juan Carlos Roa

Juan Carlos Roa

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
11474
World Ranking
17039
National Ranking
386

Overview

Juan Carlos Roa is affiliated with the University of Córdoba in Spain and specializes in the field of medicine with a focus on reproductive medicine as well as endocrine and autonomic systems. Their work also encompasses molecular biology, obstetrics and gynecology, and pediatrics, perinatology, and child health.

Their research primarily explores the hypothalamic control of reproductive hormones, ovarian function and disorders, and the regulation of appetite and obesity. Additional topics include plant reproductive biology, birth, development, and health, gestational diabetes research and management, and circadian rhythm and melatonin.

Juan Carlos Roa has published several papers recently, including:

  • "Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty" (2020, Cell Metabolism)
  • "Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation" (2021, Nature Metabolism)
  • "AMP-activated protein kinase (AMPK) signaling in GnRH neurons links energy status and reproduction" (2020, Metabolism)
  • "Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice" (2022, Nature Communications)
  • "Central and peripheral mechanisms involved in the control of GnRH neuronal function by metabolic factors" (2023, Current Opinion in Pharmacology)

They frequently publish in journals such as Metabolism, Cell Metabolism, Nature Metabolism, Nature Communications, and Current Opinion in Pharmacology.

Their frequent co-authors include:

  • Manuel Tena-Sempere (9 joint publications)
  • Inmaculada Velasco (6 joint publications)
  • Francisco Ruíz-Pino (6 joint publications)
  • María J. Vázquez (5 joint publications)
  • Carlos Diéguez (4 joint publications)

Best Publications

  • Developmental and Hormonally Regulated Messenger Ribonucleic Acid Expression of KiSS-1 and Its Putative Receptor, GPR54, in Rat Hypothalamus and Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide

    V M Navarro;J M Castellano;R Fernández-Fernández;M L Barreiro

  • Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

    Yuchen Jiao;Timothy M Pawlik;Robert A Anders;Florin M Selaru

  • Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition.

    J M Castellano;V M Navarro;R Fernández-Fernández;R Nogueiras

  • Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54

    V. M. Navarro;R. Fernández-Fernández;J. M. Castellano;J. Roa

  • Sexual differentiation of Kiss1 gene expression in the brain of the rat

    Alexander S. Kauffman;Michelle L. Gottsch;Juan Roa;Alisa C. Byquist

  • Characterization of the potent luteinizing hormone-releasing activity of KiSS-1 peptide, the natural ligand of GPR54.

    V M Navarro;J M Castellano;R Fernández-Fernández;S Tovar

  • New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function.

    Juan Roa;Enrique Aguilar;Enrique Aguilar;Carlos Dieguez;Carlos Dieguez;Leonor Pinilla;Leonor Pinilla

  • Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.

    V. M. Navarro;J. M. Castellano;R. Fernández-Fernández;S. Tovar

  • Expression of Hypothalamic KiSS-1 System and Rescue of Defective Gonadotropic Responses by Kisspeptin in Streptozotocin-Induced Diabetic Male Rats

    Juan M. Castellano;Victor M. Navarro;Rafael Fernández-Fernández;Juan Roa

  • Expression of KiSS-1 in Rat Ovary: Putative Local Regulator of Ovulation?

    J M Castellano;M Gaytan;J Roa;E Vigo

  • Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases.

    Volkan Adsay;Kee Taek Jang;Juan Carlos Roa;Nevra Dursun

  • The Mammalian Target of Rapamycin as Novel Central Regulator of Puberty Onset via Modulation of Hypothalamic Kiss1 System

    J Roa;D Garcia-Galiano;L Varela;M A Sánchez-Garrido

  • A microRNA switch regulates the rise in hypothalamic GnRH production before puberty

    Andrea Messina;Andrea Messina;Andrea Messina;Fanny Langlet;Fanny Langlet;Fanny Langlet;Konstantina Chachlaki;Konstantina Chachlaki;Juan Roa;Juan Roa

  • Tumor location is a strong predictor of tumor progression and survival in T2 gallbladder cancer: an international multicenter study.

    Junichi Shindoh;Xabier de Aretxabala;Thomas A Aloia;Juan C arlos Roa

  • Gallbladder cancer: a morphological and molecular update

    Robert David Goldin;Juan Carlos Roa

  • Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

    Noelia Martínez-Sánchez;Patricia Seoane-Collazo;Cristina Contreras;Luis Varela

  • Preneoplastic lesions in gallbladder cancer

    Iván Roa;Xabier de Aretxabala;Juan C. Araya;Juan Roa

  • KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

    Francisco Gaytan;Maria Gaytan;Juan Manuel Castellano;Magdalena Romero

  • Metabolic control of puberty onset: new players, new mechanisms.

    Juan Roa;David García-Galiano;Juan M. Castellano;Francisco Gaytan

  • Hypothalamic Expression of KiSS-1 System and Gonadotropin-Releasing Effects of Kisspeptin in Different Reproductive States of the Female Rat

    J. Roa;E. Vigo;J. M. Castellano;V. M. Navarro

Frequent Co-Authors

Manuel Tena-Sempere
Manuel Tena-Sempere University of Córdoba
Leonor Pinilla
Leonor Pinilla University of Córdoba
Carlos Dieguez
Carlos Dieguez University of Santiago de Compostela
Akhilesh Pandey
Akhilesh Pandey Mayo Clinic
Volkan Adsay
Volkan Adsay Koç University
Miguel López
Miguel López University of Santiago de Compostela
Catterina Ferreccio
Catterina Ferreccio Pontificia Universidad Católica de Chile
Sergio Lavandero
Sergio Lavandero University of Chile
Rubén Nogueiras
Rubén Nogueiras University of Santiago de Compostela
Allan Hildesheim
Allan Hildesheim National Institutes of Health

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