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Carmela R. Abraham

Carmela R. Abraham

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
16784
World Ranking
12342
National Ranking
5283

Overview

Carmela R. Abraham is affiliated with Boston University in the United States. Their research primarily spans across the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on Genetics, Nephrology, and Molecular Biology. Their work also touches on Developmental Neuroscience and Neurology.

The main topics addressed in their publications include:

  • Genetic Syndromes and Imprinting
  • Parathyroid Disorders and Treatments
  • Genetic and Kidney Cyst Diseases
  • Epigenetics and DNA Methylation
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA modifications and cancer

Their recent notable papers include:

  • "Aging-suppressor Klotho: Prospects in diagnostics and therapeutics" (2022) published in Ageing Research Reviews
  • "AAV-mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice" (2022) published in Aging Cell
  • "Klotho, PTSD, and advanced epigenetic age in cortical tissue" (2020) published in Neuropsychopharmacology
  • "Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho" (2020) published in PLoS ONE
  • "PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation" (2020) published in Psychoneuroendocrinology

Frequent co-authors collaborating with Abraham include:

  • Assumpció Bosch
  • Miguel Chillón
  • Ci-Di Chen
  • Joan Roig-Soriano
  • Ella Zeldich

They have published multiple papers in venues with recurring appearances, such as:

  • Molecular Therapy
  • Ageing Research Reviews
  • Communications Biology
  • Aging Cell
  • Neuropsychopharmacology

Best Publications

  • The spectrum of disease in chronic traumatic encephalopathy

    Ann C. McKee;Thor D. Stein;Thor D. Stein;Christopher J. Nowinski;Robert A. Stern

  • Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

    Iain L. Campbell;Carmela R. Abraham;Eliezer Masliah;Phillip Kemper

  • Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

    Carmela R. Abraham;Dennis J. Selkoe;Huntington Potter

  • Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

    Stephanie M. Toggas;Eliezer Masliah;Edward M. Rockenstein;Glenn F. Rail

  • X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation

    Daniel A. Kirschner;Carmela Abraham;Dennis J. Selkoe

  • Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

    Ci-Di Chen;Sonia Podvin;Earl Gillespie;Susan E. Leeman

  • Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease.

    Dennis J. Selkoe;Carmela R. Abraham;Marcia B. Podlisny;Lawrence K. Duffy

  • Neurobiological Bases of Age-Related Cognitive Decline in the Rhesus Monkey

    A Peters;A Peters;D L Rosene;D L Rosene;M B Moss;M B Moss;T L Kemper

  • Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

    L. Mucke;E. Masliah;W.B. Johnson;M.D. Ruppe

  • Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins

    Yasuo Ihara;Yasuo Ihara;Yasuo Ihara;Carmela Abraham;Carmela Abraham;Dennis J. Selkoe;Dennis J. Selkoe

  • Life Extension Factor Klotho Enhances Cognition

    Dena B. Dubal;Jennifer S. Yokoyama;Lei Zhu;Lauren Broestl

  • Increased microglial activation and protein nitration in white matter of the aging monkey.

    Jacob A. Sloane;William Hollander;Mark B. Moss;Mark B. Moss;Douglas L. Rosene;Douglas L. Rosene

  • Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers

    Dennis J. Selkoe;Carmela Abraham;Yasuo Ihara

  • Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles

    KS Kosik;LK Duffy;MM Dowling;C Abraham

  • The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System

    Ella Zeldich;Ci-Di Chen;Teresa A. Colvin;Erin A. Bove-Fenderson

  • The Cytosolic Endopeptidase, Thimet Oligopeptidase, Destroys Antigenic Peptides and Limits the Extent of MHC Class I Antigen Presentation

    Ian A. York;Annie X.Y. Mo;Kristen Lemerise;Wanyong Zeng

  • Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice

    Dena B. Dubal;Lei Zhu;Pascal E. Sanchez;Kurtresha Worden

  • Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

    Sergei Aleshkov;Carmela R. Abraham;Vassilis I. Zannis

  • Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA.

    J. M. Pasternack;C. R. Abraham;B. J. Van Dyke;H. Potter

  • α1‐Antichymotrypsin Binding to Alzheimer Aβ Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro

    Paul E. Fraser;Jack T. Nguyen;Donald R. McLachlan;Carmela R. Abraham

Frequent Co-Authors

Dennis J. Selkoe
Dennis J. Selkoe Brigham and Women's Hospital
Douglas L. Rosene
Douglas L. Rosene Boston University
Huntington Potter
Huntington Potter University of Colorado Anschutz Medical Campus
Lennart Mucke
Lennart Mucke University of California, San Francisco
Ann C. McKee
Ann C. McKee Boston University
Richard E. Fine
Richard E. Fine Boston University
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Tsuneya Ikezu
Tsuneya Ikezu Boston University
Mark B. Moss
Mark B. Moss Boston University
Lindsay A. Farrer
Lindsay A. Farrer Boston University

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