World's Best Scientists 2026 revealed!
Åke Engström

Åke Engström

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
13351
World Ranking
14290
National Ranking
216

Overview

Åke Engström is affiliated with Uppsala University in Sweden and has a research focus primarily in the fields of Chemistry and Biochemistry, Genetics and Molecular Biology. Within these broader disciplines, Engström's work spans several specialized subfields including Organic Chemistry, Molecular Biology, Computational Theory and Mathematics, Food Science, and Spectroscopy.

Engström's research addresses various topics such as Click Chemistry and Applications, Chemical Synthesis and Analysis, Computational Drug Discovery Methods, Fermentation and Sensory Analysis, Molecular Spectroscopy and Chirality, Synthesis and Characterization of Heterocyclic Compounds, and DNA and Nucleic Acid Chemistry.

Their recent scholarly contributions include publications in key scientific venues with the following papers:

  • Chromatographic Determination of Permeability-Relevant Lipophilicity Facilitates Rapid Analysis of Macrocyclic Peptide Scaffolds (2024), Journal of Medicinal Chemistry
  • Choreoisosteres: Pseudoatom Variation in Macrocyclic Hinges Conserves Structure and Dynamics (2025), ACS Physical Chemistry Au
  • Triazine Macrocycle Libraries: Synthesis, logD Prediction, and a Surprisingly Hydrophobic, Membrane-Permeable Diamine (2025), ACS Medicinal Chemistry Letters

Frequent collaborators with whom Engström has published multiple works include R. Scott Lokey, Alexander J. Menke, Casey J. Patterson-Gardner, Eric E. Simanek, and Grant Koch.

The prominent publication venues where Engström's research appears are:

  • Journal of Medicinal Chemistry
  • ACS Physical Chemistry Au
  • ACS Medicinal Chemistry Letters

Best Publications

  • Sequence and specificity of two antibacterial proteins involved in insect immunity

    H. Steiner;D. Hultmark;Å. Engström;H. Bennich

  • Insect Immunity: Isolation and Structure of Cecropin D and Four Minor Antibacterial Components from Cecropia Pupae

    Dan Hultmark;Åke Engström;Hans Bennich;Rashmi Kapur

  • Insect immunity. Attacins, a family of antibacterial proteins from Hyalophora cecropia.

    D. Hultmark;A. Engström;K. Andersson;H. Steiner

  • Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases.

    Kiflu Berhane;Mikael Widersten;Ake Engstrom;John W. Kozarich

  • Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases.

    Seijiro Mori;Lars Rönnstrand;Koutaro Yokote;Åke Engström

  • Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis.

    Johan Dixelius;Helena Larsson;Helena Larsson;Takako Sasaki;Takako Sasaki;Kristina Holmqvist;Kristina Holmqvist

  • The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study

    Holak Ta;Engström A;Kraulis Pj;Lindeberg G

  • Characterization of a potassium channel toxin from the Caribbean sea anemone Stichodactyla helianthus

    Olga Castañeda;Vivian Sotolongo;Ana Maria Amor;Reto Stöcklin

  • Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase

    Karin Hjalmarsson;Stefan L. Marklund;Ake Engstrom;Thomas Edlund

  • Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis

    Harald Burkhardt;Bettina Sehnert;Robert Bockermann;Åke Engström

  • Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.

    Hüseyin Uysal;Robert Bockermann;Kutty S. Nandakumar;Kutty S. Nandakumar;Bettina Sehnert

  • Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

    Omri Snir;Mona Widhe;Monika Hermansson;Caroline von Spee

  • Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles

    O. Snir;M. Widhe;C. von Spee;Johan Lindberg

  • Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis.

    Mats Sundvall;Johan Jirholt;Hai Tao Yang;Liselotte Jansson

  • Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity.

    Andrey V. Zavialov;Åke Engström

  • The hemK gene in Escherichia coli encodes the N5-glutamine methyltransferase that modifies peptide release factors

    Valérie Heurgué‐Hamard;Stéphanie Champ;Åke Engström;Måns Ehrenberg

  • Identification of an immunodominant type‐II collagen peptide recognized by T cells in H‐2q mice: self tolerance at the level of determinant selection

    Erik Michaëlsson;Mikael Andersson;Rikard Holmdahl;Åke Engström

  • A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation

    Vildan Dinçbas‐Renqvist;Åke Engström;Liliana Mora;Valérie Heurgué‐Hamard

  • Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia

    P van Hofsten;I Faye;K Kockum;J Y Lee

  • Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse.

    Harald Burkhardt;Tobias Koller;Åke Engström;Kutty Selva Nandakumar

Frequent Co-Authors

Per Jemth
Per Jemth Uppsala University
Rikard Holmdahl
Rikard Holmdahl Karolinska Institute
Stefano Gianni
Stefano Gianni Sapienza University of Rome
Hans G. Boman
Hans G. Boman Karolinska Institute
Lars Rask
Lars Rask Uppsala University
Ulf Hellman
Ulf Hellman Ludwig Cancer Research
Dan Hultmark
Dan Hultmark Umeå University
Ulf Pettersson
Ulf Pettersson Uppsala University
Lena Claesson-Welsh
Lena Claesson-Welsh Uppsala University
Anne Dell
Anne Dell Imperial College London

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