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Stefan L. Marklund

Stefan L. Marklund

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
43485
World Ranking
1872
National Ranking
30

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Stefan L. Marklund is affiliated with Umeå University in Sweden, specializing primarily in the field of Medicine with a focus on Neurology, Genetics, and Molecular Biology. Their research spans various subfields, including Pulmonary and Respiratory Medicine as well as General Health Professions. The scientist's work has contributed notably to topics such as Amyotrophic Lateral Sclerosis research, Neurogenetic and Muscular Disorders, and Parkinson's Disease mechanisms and treatments. Additional areas of study include Prion Diseases, Protein Misfolding, and Mitochondrial Function and Pathology.

Their publication record includes contributions to multiple research venues, with a concentration in journals such as Acta Neuropathologica Communications and the Journal of Neurochemistry, each hosting two of their publications. Other significant venues where their work appears include Cells, Brain, and Brain Communications.

Recent scholarly articles authored or co-authored by Stefan L. Marklund cover various aspects of neurodegenerative diseases and mitochondrial function, including:

  • "Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS," 2022, Cells
  • "Infantile SOD1 deficiency syndrome caused by a homozygous SOD1 variant with absence of enzyme activity," 2021, Brain
  • "The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1," 2022, Brain Communications
  • "Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis," 2023, Cell Reports
  • "Widespread CNS pathology in amyotrophic lateral sclerosis homozygous for the D90A SOD1 mutation," 2022, Acta Neuropathologica

Marklund frequently collaborates with a group of researchers in related fields. Their most common co-authors include:

  • Peter M. Andersen
  • Ulrika Nordström
  • Per Zetterström
  • Thomas Brännström
  • Karin Forsberg

The research topics covered in Marklund's works prominently include Amyotrophic Lateral Sclerosis research, reflecting a consistent focus on neurodegenerative conditions with genetic components. Their engagement with mitochondrial pathology and protein homeostasis aligns with their studies into the molecular underpinnings of these diseases.

Best Publications

  • Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase

    Stefan Marklund;Gudrun Marklund

  • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

    Diether Lambrechts;Erik Storkebaum;Masafumi Morimoto;Jurgen Del-Favero

  • Human copper-containing superoxide dismutase of high molecular weight

    Stefan L. Marklund

  • Toxicity of Familial ALS-Linked SOD1 Mutants from Selective Recruitment to Spinal Mitochondria

    Jian Liu;Concepción Lillo;P.Andreas Jonsson;Christine Vande Velde

  • CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse.

    K Grankvist;S L Marklund;I B Täljedal

  • Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species

    S L Marklund

  • Widespread Origins of Domestic Horse Lineages

    Carles Vilà;Jennifer A. Leonard;Anders Götherström;Stefan Marklund

  • Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia.

    L M Carlsson;J Jonsson;T Edlund;S L Marklund

  • Superoxide dismutase in extracellular fluids

    Stefan L. Marklund;Elisabeth Holme;Louise Hellner

  • Extraction and GC/MS Analysis of the Human Blood Plasma Metabolome

    A Jiye;Johan Trygg;Jonas Gullberg;Annika I. Johansson

  • Extracellular superoxide dismutase in human tissues and human cell lines.

    Stefan L. Marklund

  • The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase

    Pontus Strålin;Kurt Karlsson;Bengt O. Johansson;Stefan L. Marklund

  • High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses.

    Pär Jonsson;Annika I. Johansson;Jonas Gullberg;Johan Trygg

  • SPECTROPHOTOMETRIC STUDY OF SPONTANEOUS DISPROPORTIONATION OF SUPEROXIDE ANION RADICAL AND SENSITIVE DIRECT ASSAY FOR SUPEROXIDE DISMUTASE.

    S Marklund

  • Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase.

    Peter M. Andersen;Peter Nilsson;Veli Ala-Hurula;Marja-Leena Keränen

  • Phenotypic heterogeneity in motor neuron disease patients with CuZn-superoxide dismutase mutations in Scandinavia.

    P M Andersen;P Nilsson;M L Keränen;L Forsgren

  • Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients

    Karin Forsberg;P. Andreas Jonsson;Peter M. Andersen;Daniel Bergemalm

  • The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle.

    Brian R. Barnes;Stefan Marklund;Tatiana L. Steiler;Mark Walter

  • Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.

    P. Andreas Jonsson;Karin Ernhill;Peter M. Andersen;Daniel Bergemalm

  • Expression of Extracellular SOD and iNOS in Macrophages and Smooth Muscle Cells in Human and Rabbit Atherosclerotic Lesions Colocalization With Epitopes Characteristic of Oxidized LDL and Peroxynitrite-Modified Proteins

    Jukka S. Luoma;Pontus Strålin;Stefan L. Marklund;Timo P. Hiltunen

Frequent Co-Authors

Peter M Andersen
Peter M Andersen Umeå University
Thomas Edlund
Thomas Edlund Umeå University
Thomas Moritz
Thomas Moritz Swedish University of Agricultural Sciences
Göran Hallmans
Göran Hallmans Umeå University
Bengt Winblad
Bengt Winblad Karolinska Institute
Seppo Ylä-Herttuala
Seppo Ylä-Herttuala University of Eastern Finland
Ammar Al-Chalabi
Ammar Al-Chalabi King's College London
Rolf Adolfsson
Rolf Adolfsson Umeå University
Christopher Shaw
Christopher Shaw King's College London

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