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Chemistry

D-Index
73
Citations
19399
World Ranking
4951
National Ranking
917

Overview

Guangji Wang is affiliated with China Pharmaceutical University in China. Their research spans mainly the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Pharmacology, Oncology, Cancer Research, and Epidemiology.

Their work covers several specialized topics, including:

  • Cancer, Hypoxia, and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Drug Transport and Resistance Mechanisms
  • Metabolomics and Mass Spectrometry Studies
  • Gut microbiota and health
  • Ginseng Biological Effects and Applications
  • Drug-Induced Hepatotoxicity and Protection

Guangji Wang has contributed to numerous publications in frequent venues such as:

  • Acta Pharmaceutica Sinica B
  • Phytomedicine
  • Journal of Pharmaceutical and Biomedical Analysis
  • Drug Metabolism and Disposition
  • Frontiers in Pharmacology

Among their recent papers are:

  • "Gut Microbial Metabolites of Aromatic Amino Acids as Signals in Host-Microbe Interplay" (2020) published in Trends in Endocrinology and Metabolism
  • "Cyclic immonium ion of lactyllysine reveals widespread lactylation in the human proteome" (2022) published in Nature Methods
  • "Bacteroides species differentially modulate depression-like behavior via gut-brain metabolic signaling" (2022) published in Brain Behavior and Immunity
  • "Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition" (2020) published in Cell Metabolism
  • "SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis" (2020) published in Nature Communications

Collaborative work is a significant aspect of Guangji Wang's research, with frequent co-authors including Haiping Hao, Fang Zhou, Jiye Aa, Le Zhen, and Jingwei Zhang. The collaborative count with these colleagues ranges from 14 to 32 joint works, reflecting ongoing partnerships in related research areas.

Best Publications

  • Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis

    Haiping Hao;Lijuan Cao;Changtao Jiang;Changtao Jiang;Yuan Che

  • Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats

    Yi-Tong Liu;Hai-Ping Hao;Hong-Guang Xie;Li Lai

  • Cyclic immonium ion of lactyllysine reveals widespread lactylation in the human proteome

    Unknown

  • Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages.

    Xiaoxuan Zhang;Guangji Wang;Emily C. Gurley;Huiping Zhou

  • Drugs as CYP3A probes, inducers, and inhibitors.

    Yi-Tong Liu;Hai-Ping Hao;Chang-Xiao Liu;Guang-Ji Wang

  • Gut Microbial Metabolites of Aromatic Amino Acids as Signals in Host–Microbe Interplay

    Yali Liu;Yuanlong Hou;Guangji Wang;Xiao Zheng

  • Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats

    Tong Lu;Jue Song;Fang Huang;Yuanxiong Deng

  • Betulinic Acid and its Derivatives as Potential Antitumor Agents

    Dong-Mei Zhang;Hong-Gui Xu;Lei Wang;Ying-Jie Li

  • The Antihyperglycaemic Activity of Berberine Arises from a Decrease of Glucose Absorption

    Guo-Yu Pan;Zhi-Jiang Huang;Guang-Ji Wang;J. Paul Fawcett

  • Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway.

    Runbin Sun;Na Yang;Bo Kong;Bei Cao

  • Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1‐phosphate receptor 2

    Runping Liu;Renping Zhao;Xiqiao Zhou;Xiuyin Liang

  • Differences in metabolite profile between blood plasma and serum.

    Linsheng Liu;Jiye Aa;Guangji Wang;Bei Yan

  • Intracellular delivery and antitumor effects of a redox-responsive polymeric paclitaxel conjugate based on hyaluronic acid

    Shaoping Yin;Jue Huai;Xi Chen;Yong Yang

  • High performance liquid chromatographic-mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic studies.

    Hai-Tang Xie;Guang-Ji Wang;Jian-Guo Sun;Ian Tucker

  • Rapid identification of ophiopogonins and ophiopogonones in Ophiopogon japonicus extract with a practical technique of mass defect filtering based on high resolution mass spectrometry.

    Tong Xie;Yan Liang;Haiping Hao;Jiye A

  • Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice.

    Caixia Yan;Yirui Zhang;Xiaoxu Zhang;Jiye Aa

  • PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis

    Xueyan Zhou;Lijuan Cao;Changtao Jiang;Yang Xie

  • Pharmacokinetic characterization of ginsenoside Rh2, an anticancer nutrient from ginseng, in rats and dogs

    Yi Gu;Guang-Ji Wang;Jian-Guo Sun;Yuan-Wei Jia

  • Modulation of glucagon-like peptide-1 release by berberine: In vivo and in vitro studies

    Yunli Yu;Li Liu;Xinting Wang;Xiang Liu

  • Herbal drug discovery for the treatment of nonalcoholic fatty liver disease

    Tingting Yan;Nana Yan;Ping Wang;Ping Wang;Yangliu Xia;Yangliu Xia

  • Global Detection and Identification of Nontarget Components from Herbal Preparations by Liquid Chromatography Hybrid Ion Trap Time-of-Flight Mass Spectrometry and a Strategy

    Haiping Hao;Nan Cui;Guangji Wang;Binren Xiang

  • Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes.

    Furong Qiu;Rong Zhang;Jianguo Sun;Jiye A

  • Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example.

    Chaonan Zheng;Haiping Hao;Xuan Wang;Xiaolan Wu

  • Enantioselective Pharmacokinetics of Ibuprofen and Involved Mechanisms

    Haiping Hao;Guangji Wang;Jianguo Sun

Frequent Co-Authors

Huiping Zhou
Huiping Zhou University of Tsukuba
Phillip B. Hylemon
Phillip B. Hylemon Virginia Commonwealth University
Michael S. Roberts
Michael S. Roberts University of Queensland
William M. Pandak
William M. Pandak Virginia Commonwealth University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Paul F. Smith
Paul F. Smith University of Otago
Bruce C. Baguley
Bruce C. Baguley University of Auckland
Kristopher W. Krausz
Kristopher W. Krausz National Institutes of Health
Dirk De Ridder
Dirk De Ridder University of Otago
Yong Jiang
Yong Jiang Peking University

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