World's Best Scientists 2026 revealed!
Jules A. Hoffmann

Jules A. Hoffmann

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
114
Citations
64318
World Ranking
816
National Ranking
14

Jules A. Hoffmann publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jules A. Hoffmann sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 258 publications — 69th percentile

69% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jules A. Hoffmann D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jules A. Hoffmann sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 114 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award
  • 2022 - Research.com Biology and Biochemistry in France Leader Award

Overview

Jules A. Hoffmann is affiliated with the University of Strasbourg in France. Their research primarily focuses on immunology and microbiology, with a particular emphasis on the invertebrate immune response mechanisms and neurobiology related to insect physiology.

The scientist has contributed to a number of recent publications that highlight several themes in innate immunity and insect biology. Notable recent papers include:

  • A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium, 2023, published in Proceedings of the National Academy of Sciences
  • Global public health crisis response: A roundtable discussion with Professor George Fu Gao, Professor Jules A Hoffmann, Professor Chris Walzer and Professor Jiahai Lu, 2023, published in hLife
  • Toll-9 prevents the proliferation of injected oncogenic cells in adult flies, 2024, published in Journal of genetics and genomics/Journal of Genetics and Genomics
  • Toll-mediated airway homeostasis is essential for fly survival upon injection of RasV12-GFP oncogenic cells, 2024, published in Cell Reports
  • hLife: Linking basic research and clinical applications, 2023, published in hLife

The primary fields of study represented in their work include immunology, cellular and molecular neuroscience, insect science, molecular biology, and radiology, nuclear medicine, and imaging. Subfields cover:

  • Immunology
  • Cellular and Molecular Neuroscience
  • Insect Science
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging

Research topics commonly explored by Hoffmann include:

  • Invertebrate Immune Response Mechanisms
  • Neurobiology and Insect Physiology Research
  • Insect symbiosis and bacterial influences
  • Viral Infectious Diseases and Gene Expression in Insects
  • Insect Utilization and Effects
  • Aquaculture disease management and microbiota
  • Historical Medical Research and Treatments

Frequently publishing in venues such as Proceedings of the National Academy of Sciences, hLife, Journal of genetics and genomics/Journal of Genetics and Genomics, Cell Reports, and Biologie Aujourd hui, Hoffmann has established a consistent presence in journals that focus on interdisciplinary aspects of immunology and molecular biology related to insects.

Collaborations feature repeated partnerships with researchers like Shanming Ji, Xiaojing Zhou, Jiyong Liu, Di Chen, and Xiaoming Huang, reflecting a network of coauthors involved in related fields of genetic and immunological studies in insects and molecular pathways.

Best Publications

  • The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

    Bruno Lemaitre;Emmanuelle Nicolas;Lydia Michaut;Jean-Marc Reichhart

  • The Host Defense of Drosophila melanogaster

    Bruno Lemaitre;Jules Hoffmann

  • Phylogenetic Perspectives in Innate Immunity

    Jules A. Hoffmann;Fotis C. Kafatos;Charles A. Janeway;R. A. B. Ezekowitz

  • The immune response of Drosophila.

    Jules A. Hoffmann

  • The role of neuropeptide Y in the antiobesity action of the obese gene product.

    T W Stephens;M Basinski;P K Bristow;J M Bue-Valleskey

  • Drosophila innate immunity: an evolutionary perspective.

    Jules A. Hoffmann;Jean-Marc Reichhart

  • Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

    Bruno Lemaitre;Jean-Marc Reichhart;Jules A. Hoffmann

  • Immunity-Related Genes and Gene Families in Anopheles gambiae

    George K. Christophides;Evgeny Zdobnov;Carolina Barillas-Mury;Ewan Birney

  • The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections

    Dominique Ferrandon;Jean-Luc Imler;Charles Hetru;Jules A. Hoffmann

  • Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

    Tatiana Michel;Jean-Marc Reichhart;Jules A. Hoffmann;Julien Royet

  • The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila.

    Catherine Dostert;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Phil Irving;Laurent Troxler

  • A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

    Bruno Lemaitre;Elisabeth Kromer-Metzger;Lydia Michaut;Emmanuelle Nicolas

  • Innate immunity of insects

    Jules A Hoffmann

  • Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia

    Phoebe Tzou;Serge Ohresser;Dominique Ferrandon;Maria Capovilla

  • The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein

    Marie Gottar;Vanessa Gobert;Tatiana Michel;Marcia Belvin

  • Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila

    Elena A. Levashina;Emma Langley;Clare Green;David Gubb

  • Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila

    Delphine Galiana-Arnoux;Catherine Dostert;Anette Schneemann;Jules A Hoffmann

  • Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides.

    P Fehlbaum;P Bulet;L Michaut;M Lagueux

  • A genome-wide analysis of immune responses in Drosophila

    Phil Irving;Laurent Troxler;Timothy S. Heuer;Marcia Belvin

  • Toll receptors in innate immunity

    Jean-Luc Imler;Jules A. Hoffmann

Frequent Co-Authors

Charles Hetru
Charles Hetru Institute for Molecular and Cellular Biology
Jean-Marc Reichhart
Jean-Marc Reichhart University of Strasbourg
Philippe Bulet
Philippe Bulet Grenoble Alpes University
Jean-Luc Imler
Jean-Luc Imler University of Strasbourg
Bruno Lemaitre
Bruno Lemaitre École Polytechnique Fédérale de Lausanne
Philippe Georgel
Philippe Georgel University of Strasbourg
Elena A. Levashina
Elena A. Levashina Max Planck Institute for Infection Biology
Alain Van Dorsselaer
Alain Van Dorsselaer University of Strasbourg
Osamu Takeuchi
Osamu Takeuchi Kyoto University
R. Alan B. Ezekowitz
R. Alan B. Ezekowitz Harvard University

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