Charles Hetru focuses on Innate immune system, Genetics, Gene, Peptide and Biochemistry. His Innate immune system research incorporates elements of Transcription factor, Drosophila Protein, Microbiology and Antimicrobial peptides. His research in Genome, Drosophila, Drosophila melanogaster, Mutant and Whole genome sequencing are components of Genetics.
In general Gene, his work in Molecular evolution is often linked to DNA methylation linking many areas of study. His Peptide study incorporates themes from Molecular mass, Peptide sequence, Glycosylation and Antibacterial agent. His work in the fields of Disulfide bond, Glycine and Mode of action overlaps with other areas such as Structure and function.
His main research concerns Biochemistry, Ecdysone, Peptide, Stereochemistry and Microbiology. His Biochemistry research incorporates themes from Follicle, Insect and Antibacterial agent, Bacteria. His work carried out in the field of Ecdysone brings together such families of science as In vitro, Biosynthesis and Hydroxylation.
His Peptide study combines topics from a wide range of disciplines, such as Amino acid, Peptide sequence, Edman degradation, Antifungal and Antibacterial peptide. His work deals with themes such as Innate immune system, Signal transduction, Cell biology and Gram-negative bacteria, which intersect with Antimicrobial peptides. Charles Hetru combines subjects such as Drosophila melanogaster, Gene and Drosophila with his study of Innate immune system.
Genetics, Innate immune system, Drosophila melanogaster, Drosophila and Cell biology are his primary areas of study. His biological study deals with issues like Signal transduction, which deal with fields such as Chromatin remodeling. His Drosophila melanogaster research is multidisciplinary, relying on both Organism, Pathogen and Model organism.
His Drosophila research is multidisciplinary, incorporating elements of Immune system, Pseudomonas aeruginosa, Insect, Regulation of gene expression and Computational biology. In general Insect study, his work on Red flour beetle often relates to the realm of Anopheles, thereby connecting several areas of interest. His Cell biology research includes themes of Pattern recognition receptor, Drosophila Protein and Antimicrobial peptides.
Charles Hetru mostly deals with Genetics, Drosophila, Drosophila melanogaster, Innate immune system and Gene. His studies deal with areas such as Insect and Immune system, Immunity as well as Drosophila. His research in Immunity intersects with topics in Reprogramming and Antimicrobial peptides.
His work on Drosophila C virus as part of general Drosophila melanogaster study is frequently linked to JAK-STAT signaling pathway, bridging the gap between disciplines. Charles Hetru undertakes interdisciplinary study in the fields of Innate immune system and STAT protein through his research. His work in Gene covers topics such as Red flour beetle which are related to areas like RNA interference.
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Insights into social insects from the genome of the honeybee Apis mellifera
George M. Weinstock;Gene E. Robinson;Richard A. Gibbs;Kim C. Worley.
The genome of the model beetle and pest Tribolium castaneum.
Stephen Richards;Richard A. Gibbs;George M. Weinstock;Susan J. Brown.
Antimicrobial peptides in insects; structure and function
Phillipe Bulet;Charles Hetru;Jean-Luc Dimarcq;Daniéle Hoffmann.
Developmental and Comparative Immunology (1999)
Immunity-Related Genes and Gene Families in Anopheles gambiae
George K. Christophides;Evgeny Zdobnov;Carolina Barillas-Mury;Ewan Birney.
Immune pathways and defence mechanisms in honey bees Apis mellifera
J D Evans;K Aronstein;Y P Chen;C Hetru.
Insect Molecular Biology (2006)
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
Dominique Ferrandon;Jean-Luc Imler;Charles Hetru;Jules A. Hoffmann.
Nature Reviews Immunology (2007)
The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila.
Catherine Dostert;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Phil Irving;Laurent Troxler.
Nature Immunology (2005)
A genome-wide analysis of immune responses in Drosophila
Phil Irving;Laurent Troxler;Timothy S. Heuer;Marcia Belvin.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides.
P Fehlbaum;P Bulet;L Michaut;M Lagueux.
Journal of Biological Chemistry (1994)
Innate Immunity: ISOLATION OF SEVERAL CYSTEINE-RICH ANTIMICROBIAL PEPTIDES FROM THE BLOOD OF A MOLLUSC, MYTILUS EDULIS
Maurice Charlet;Serguey Chernysh;Hervé Philippe;Charles Hetru.
Journal of Biological Chemistry (1996)
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