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Chemistry

D-Index
63
Citations
12768
World Ranking
8519
National Ranking
54

Overview

Klaus R. Liedl is affiliated with the University of Innsbruck in Austria. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with significant contributions also in medicine. The scientist's work encompasses subfields such as molecular biology, materials chemistry, radiology, nuclear medicine and imaging, spectroscopy, and immunology and allergy.

The primary topics covered in Klaus R. Liedl's research include:

  • Monoclonal and Polyclonal Antibodies Research
  • Protein Structure and Dynamics
  • Glycosylation and Glycoproteins Research
  • Ion channel regulation and function
  • Protein purification and stability
  • Cardiac electrophysiology and arrhythmias
  • Neuroscience and Neural Engineering

Their recent publications reflect a focus on immunology, protein dynamics, and neurological disorders. Selected papers include:

  • "Broadly neutralizing antibodies target a haemagglutinin anchor epitope," 2021, Nature
  • "Catalytic Site pKa Values of Aspartic, Cysteine, and Serine Proteases: Constant pH MD Simulations," 2020, Journal of Chemical Information and Modeling
  • "Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses," 2020, Immunity
  • "Assessing developability early in the discovery process for novel biologics," 2023, mAbs
  • "CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders," 2021, Brain

Klaus R. Liedl frequently collaborates with several co-authors, including:

  • Monica L. Fernández-Quintero
  • Anna S. Kamenik
  • Franz Waibl
  • Dennis F. Dinu
  • Florian Hofer

The researcher has published extensively in various scientific journals and venues. The most frequent publication venues include:

  • Biophysical Journal
  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Chemical Information and Modeling
  • Frontiers in Molecular Biosciences

Best Publications

  • BORN-OPPENHEIMER AB INITIO QM/MM DYNAMICS SIMULATIONS OF NA+ AND K+ IN WATER : FROM STRUCTURE MAKING TO STRUCTURE BREAKING EFFECTS

    Anan Tongraar;Klaus R. Liedl;Bernd M. Rode

  • Ice nucleation by water-soluble macromolecules

    B. G. Pummer;Carsten Budke;S. Augustin-Bauditz;D. Niedermeier;D. Niedermeier

  • Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation.

    Klaus Lindauer;Thomas Loerting;Klaus R. Liedl;Romano T. Kroemer

  • How to optimize shape-based virtual screening: choosing the right query and including chemical information.

    Johannes Kirchmair;Simona Distinto;Patrick Markt;Daniela Schuster

  • A QM/MM simulation method applied to the solution of Li + in liquid ammonia

    Teerakiat Kerdcharoen;Klaus R. Liedl;Bernd M. Rode

  • Identification of Novel Functional Inhibitors of Acid Sphingomyelinase

    Johannes Kornhuber;Markus Muehlbacher;Markus Muehlbacher;Stefan Trapp;Stefanie Pechmann

  • On the Surprising Kinetic Stability of Carbonic Acid (H2CO3)

    Thomas Loerting;Christofer Tautermann;Romano T. Kroemer;Ingrid Kohl

  • Heteroaromatic π-stacking energy landscapes.

    Roland G. Huber;Michael A. Margreiter;Julian E. Fuchs;Susanne von Grafenstein

  • CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels.

    Alexandra Pinggera;Andreas Lieb;Bruno Benedetti;Michaela Lampert

  • Solvation of Ca2+ in Water Studied by Born−Oppenheimer ab Initio QM/MM Dynamics

    Anan Tongraar;Klaus R. Liedl;Bernd M. Rode

  • Influenza neuraminidase: A druggable target for natural products

    Ulrike Grienke;Michaela Schmidtke;Susanne von Grafenstein;Johannes Kirchmair

  • Qualitative prediction of blood-brain barrier permeability on a large and refined dataset.

    Markus Muehlbacher;Gudrun M. Spitzer;Klaus R. Liedl;Johannes Kornhuber

  • Carbonic Acid in the Gas Phase and Its Astrophysical Relevance

    Wolfgang Hage;Klaus R. Liedl;Andreas Hallbrucker;Erwin Mayer

  • Characterization of the vitamin E-binding properties of human plasma afamin.

    Andreas F. Voegele;Lidija Jerkovic;Bernd Wellenzohn;Patricia Eller

  • DPPC-cholesterol phase diagram using coarse-grained Molecular Dynamics simulations.

    Yin Wang;Paraskevi Gkeka;Julian E. Fuchs;Klaus R. Liedl

  • Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai.

    Ulrike Grienke;Michaela Schmidtke;Johannes Kirchmair;Kathrin Pfarr

  • The Protein Data Bank (PDB), its related services and software tools as key components for in silico guided drug discovery.

    Johannes Kirchmair;Patrick Markt;Simona Distinto;Daniela Schuster

  • Toward elimination of discrepancies between theory and experiment: the rate constant of the atmospheric conversion of SO3 to H2SO4.

    Thomas Loerting;Klaus R. Liedl

  • The hydration shell structure of Li+ investigated by Born–Oppenheimer ab initio QM/MM dynamics

    Anan Tongraar;Klaus R Liedl;Bernd M Rode

  • A critical analysis of electronic density functionals for structural, energetic, dynamic, and magnetic properties of hydrogen fluoride clusters

    Christoph Maerker;Paul Von R. Schleyer;Klaus R. Liedl;T.-K. Ha

Frequent Co-Authors

Thomas Loerting
Thomas Loerting University of Innsbruck
Erwin Mayer
Erwin Mayer University of Innsbruck
Bernd M. Rode
Bernd M. Rode University of Innsbruck
Andreas Hallbrucker
Andreas Hallbrucker University of Innsbruck
Klaus Wurst
Klaus Wurst University of Innsbruck
Bernhard Kräutler
Bernhard Kräutler University of Innsbruck
Christoph A. Sotriffer
Christoph A. Sotriffer University of Würzburg
Gerhard Wolber
Gerhard Wolber Freie Universität Berlin
Rainer Pöttgen
Rainer Pöttgen University of Münster
Daniela Schuster
Daniela Schuster Paracelsus Medical University

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