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D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
20289
World Ranking
7294
National Ranking
228

Overview

Tonghui Ma is affiliated with Dalian Medical University in China. Their research broadly covers medicine, with a significant focus on biochemistry, genetics, and molecular biology. Their work spans several specialized subfields, including molecular biology, epidemiology, organic chemistry, oncology, and neurology.

The scientist's research has contributed to topics such as natural product bioactivities and synthesis, antifungal resistance and susceptibility, fungal infections and studies, ion transport and channel regulation, biological activity of diterpenoids and biflavonoids, antibiotic resistance in bacteria, and autophagy in disease and therapy.

Frequent co-authors in Tonghui Ma's collaborations include Lingling Jin, Muhammad Noman Khan, Longfei Yang, Zhiming Ma, and Yujie Sui.

They have published multiple papers in a diverse range of reputable journals. Notable recent papers include:

  • PRAS40 hyperexpression promotes hepatocarcinogenesis, 2020, EBioMedicine
  • Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells, 2020, OncoTargets and Therapy
  • Brevilin A induces ROS-dependent apoptosis and suppresses STAT3 activation by direct binding in human lung cancer cells, 2020, Journal of Cancer
  • AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Nav1.6-Mediated Astrocyte Autophagy, 2023, Advanced Science
  • Gold(I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting thioredoxin reductase, 2023, Redox Biology

Major venues where Tonghui Ma has frequently published include The Journal of Animal and Plant Sciences, Redox Biology, Frontiers in Pharmacology, Journal of Ethnopharmacology, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion

    Tonghui Ma;Jay R. Thiagarajah;Hong Yang;Nitin D. Sonawane

  • Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels.

    Tonghui Ma;Yualin Song;Annemarie Gillespie;Elaine J. Carlson

  • Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues.

    Hajime Hasegawa;Tonghui Ma;William Skach;Michael A. Matthay

  • Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels

    Tonghui Ma;Baoxue Yang;Annemarie Gillespie;Elaine J. Carlson

  • Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.

    T Ma;B Yang;A Gillespie;E J Carlson

  • Lung fluid transport in aquaporin-5 knockout mice

    Tonghui Ma;Norimasa Fukuda;Yuanlin Song;Michael A. Matthay

  • Aquaporin water channels in gastrointestinal physiology

    Tonghui Ma;A. S. Verkman

  • Water transport across mammalian cell membranes.

    A. S. Verkman;A. N. van Hoek;T. Ma;A. Frigeri

  • Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice.

    Chunxue Bai;Norimasa Fukuda;Yualin Song;Tonghui Ma

  • Selectively reduced glycerol in skin of aquaporin-3-deficient mice may account for impaired skin hydration, elasticity, and barrier recovery.

    Mariko Hara;Tonghui Ma;A.S. Verkman

  • Impaired Stratum Corneum Hydration in Mice Lacking Epidermal Water Channel Aquaporin-3

    Tonghui Ma;Mariko Hara;Rachid Sougrat;Jean-Marc Verbavatz

  • Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study.

    J.-M. Verbavatz;D. Brown;I. Sabolic;G. Valenti

  • Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice

    Chung-Lin Chou;Mark A. Knepper;Alfred N. van Hoek;Dennis Brown

  • Cloning of a Novel Water and Urea-Permeable Aquaporin from Mouse Expressed Strongly in Colon, Placenta, Liver, and Heart

    Tonghui Ma;Baoxue Yang;A.S. Verkman

  • Nanomolar Affinity Small Molecule Correctors of Defective ΔF508-CFTR Chloride Channel Gating

    Hong Yang;Anang A. Shelat;R. Kiplin Guy;Vadiraj S. Gopinath

  • Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes.

    Baoxue Yang;Norimasa Fukuda;Alfred van Hoek;Michael A. Matthay

  • Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4

    Jean-Marc Verbavatz;Tonghui Ma;Renée Gobin;A. S. Verkman

  • High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening.

    Tonghui Ma;L. Vetrivel;Hong Yang;Nicoletta Pedemonte

  • Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice

    C. L. Chou;Tonghui Ma;Baoxue Yang;Mark A. Knepper

  • Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter.

    Tonghui Ma;A. Frigeri;H. Hasegawa;A. S. Verkman

Frequent Co-Authors

Alan S. Verkman
Alan S. Verkman University of California, San Francisco
Baoxue Yang
Baoxue Yang Peking University
Antonio Frigeri
Antonio Frigeri University of Bari Aldo Moro
William R. Skach
William R. Skach Cystic Fibrosis Foundation
Michael A. Matthay
Michael A. Matthay University of California, San Francisco
Dennis Brown
Dennis Brown Harvard University
Luis J. V. Galietta
Luis J. V. Galietta Telethon Institute Of Genetics And Medicine
Geoffrey T. Manley
Geoffrey T. Manley University of California, San Francisco
Mark J. Kurth
Mark J. Kurth University of California, Davis
Charles J. Epstein
Charles J. Epstein University of California, San Francisco

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