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Baoxue Yang

Baoxue Yang

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
14408
World Ranking
10750
National Ranking
339

Overview

Baoxue Yang is affiliated with Peking University in China. Their research spans several fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, as well as Medicine. Significant contributions have been made in the subfields of Molecular Biology, Pulmonary and Respiratory Medicine, Surgery, Biochemistry, and Genetics.

Yang's work addresses key scientific topics including:

  • Ion Transport and Channel Regulation
  • Electrolyte and hormonal disorders
  • Metabolism and Genetic Disorders
  • Amino Acid Enzymes and Metabolism
  • Genetic and Kidney Cyst Diseases
  • Renal and related cancers
  • Ion channel regulation and function

Their recent notable publications include the following papers:

  • "Ganoderic Acids Prevent Renal Ischemia Reperfusion Injury by Inhibiting Inflammation and Apoptosis," 2021, International Journal of Molecular Sciences
  • "Ganoderma lucidum polysaccharide peptide alleviates hyperuricemia by regulating adenosine deaminase and urate transporters," 2022, Food & Function
  • "Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines," 2020, Aging Cell
  • "Drug development in targeting ion channels for brain edema," 2020, Acta Pharmacologica Sinica
  • "Ganoderic acid A is the effective ingredient of Ganoderma triterpenes in retarding renal cyst development in polycystic kidney disease," 2020, Acta Pharmacologica Sinica

Yang frequently publishes in several academic journals and venues, with multiple papers appearing in:

  • Advances in Experimental Medicine and Biology
  • Sub-cellular Biochemistry / Subcellular Biochemistry
  • Acta Pharmacologica Sinica
  • SSRN Electronic Journal
  • International Journal of Molecular Sciences

Collaborations are an important aspect of Yang's research activities. Frequent coauthors include:

  • Min Li
  • Jinzhao He
  • Guangying Shao
  • Jia Meng
  • Hong Zhou

Yang's contributions reflect an interdisciplinary approach to understanding and addressing complex biological and medical issues, particularly in the regulation of ion channels, genetic diseases, and metabolism-related disorders.

Best Publications

  • Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels

    Tonghui Ma;Baoxue Yang;Annemarie Gillespie;Elaine J. Carlson

  • Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.

    T Ma;B Yang;A Gillespie;E J Carlson

  • Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes.

    Baoxue Yang;A.S. Verkman

  • The Mercurial Insensitive Water Channel (AQP-4) Forms Orthogonal Arrays in Stably Transfected Chinese Hamster Ovary Cells

    Baoxue Yang;Dennis Brown;A.S. Verkman

  • Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice

    Chung-Lin Chou;Mark A. Knepper;Alfred N. van Hoek;Dennis Brown

  • Urea-selective Concentrating Defect in Transgenic Mice Lacking Urea Transporter UT-B

    Baoxue Yang;Lise Bankir;Lise Bankir;Annemarie Gillespie;Charles J. Epstein

  • Small-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease

    Baoxue Yang;Nitin D. Sonawane;Dan Zhao;Stefan Somlo

  • Cloning of a Novel Water and Urea-Permeable Aquaporin from Mouse Expressed Strongly in Colon, Placenta, Liver, and Heart

    Tonghui Ma;Baoxue Yang;A.S. Verkman

  • Urea and urine concentrating ability: new insights from studies in mice.

    Baoxue Yang;Lise Bankir

  • Glial Cell Aquaporin-4 Overexpression in Transgenic Mice Accelerates Cytotoxic Brain Swelling

    Baoxue Yang;Zsolt Zador;A S Verkman

  • Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes.

    Baoxue Yang;Norimasa Fukuda;Alfred van Hoek;Michael A. Matthay

  • Phenotype analysis of aquaporin-8 null mice.

    Baoxue Yang;Yuanlin Song;Dan Zhao;A. S. Verkman

  • ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.

    Mariko Hara-Chikuma;Baoxue Yang;N.D. Sonawane;Sei Sasaki

  • Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus.

    Baoxue Yang;Annemarie Gillespie;Elaine J. Carlson;Charles J. Epstein

  • Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice

    C. L. Chou;Tonghui Ma;Baoxue Yang;Mark A. Knepper

  • Expression of aquaporin water channels in mouse spinal cord.

    K Oshio;D.K Binder;B Yang;S Schecter

  • Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice.

    A. S. Verkman;Baoxue Yang;Yuanlin Song;Geoffrey T. Manley

  • Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice

    Baoxue Yang;Hans G. Folkesson;Jian Yang;Michael A. Matthay

  • cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.

    Baoxue Yang;Tonghui Ma;A.S. Verkman

  • Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes.

    Baoxue Yang;A.S. Verkman

Frequent Co-Authors

Alan S. Verkman
Alan S. Verkman University of California, San Francisco
Tonghui Ma
Tonghui Ma Dalian Medical University
Michael A. Matthay
Michael A. Matthay University of California, San Francisco
Charles J. Epstein
Charles J. Epstein University of California, San Francisco
Dennis Brown
Dennis Brown Harvard University
Janet D. Klein
Janet D. Klein Emory University
Yi Sun
Yi Sun Zhejiang University
Yingjie Li
Yingjie Li Anhui University of Technology
Geoffrey T. Manley
Geoffrey T. Manley University of California, San Francisco
Qiang Zhang
Qiang Zhang Peking University

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