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Biology and Biochemistry

D-Index
54
Citations
11266
World Ranking
15564
National Ranking
1095

Overview

Walter Nickel is affiliated with Heidelberg University in Germany and focuses their research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Cell Biology, Physiology, Immunology, and Infectious Diseases.

Their research topics cover areas such as Lipid Membrane Structure and Behavior, Erythrocyte Function and Pathophysiology, Cellular Transport and Secretion, Fibroblast Growth Factor Research, Advanced Fluorescence Microscopy Techniques, Pancreatic Function and Diabetes, and Neuroscience and Neuropharmacology Research.

Nickel's recent publications include the following:

  • IFITM3 blocks influenza virus entry by sorting lipids and stabilizing hemifusion (2023, Cell Host & Microbe)
  • FGF2 and IL-1β - explorers of unconventional secretory pathways at a glance (2020, Journal of Cell Science)
  • The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2 (2020, Communications Biology)
  • Unconventional secretion mediated by direct protein self-translocation across the plasma membranes of mammalian cells (2022, Trends in Biochemical Sciences)
  • Glypican-1 drives unconventional secretion of fibroblast growth factor 2 (2022, eLife)

Frequent co-authors collaborating on these research topics include Fabio Lolicato, Roberto Saleppico, Helge Ewers, Hans-Michael Müller, and Martin Hof.

In terms of publication venues, Nickel most commonly publishes in bioRxiv (Cold Spring Harbor Laboratory), eLife, Faraday Discussions, Biophysical Journal, and Communications Biology.

Best Publications

  • Mechanisms of regulated unconventional protein secretion

    Walter Nickel;Catherine Rabouille

  • The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes.

    Walter Nickel

  • Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells.

    Walter Nickel

  • Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors

    Martina Bremser;Walter Nickel;Michael Schweikert;Mariella Ravazzola

  • Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells

    Walter Nickel;Matthias Seedorf

  • Loss of ceramide synthase 3 causes lethal skin barrier disruption

    Richard Jennemann;Mariona Rabionet;Karin Gorgas;Sharon Epstein

  • Diversity in unconventional protein secretion.

    Catherine Rabouille;Vivek Malhotra;Walter Nickel

  • Evidence for Segregation of Sphingomyelin and Cholesterol during Formation of Copi-Coated Vesicles

    Britta Brügger;Roger Sandhoff;Sabine Wegehingel;Karin Gorgas

  • Regulated secretion of macrophage migration inhibitory factor is mediated by a non‐classical pathway involving an ABC transporter

    Oliver Flieger;André Engling;Richard Bucala;Hongqi Lue

  • Functional architecture of an intracellular membrane t-SNARE

    Ryouichi Fukuda;James A. McNew;James A. McNew;Thomas Weber;Thomas Weber;Francesco Parlati

  • Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

    F Martín-Sánchez;C Diamond;C Diamond;M Zeitler;A I Gomez

  • Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs

    Walter Nickel;Thomas Weber;James A. McNew;Francesco Parlati

  • Pathways of unconventional protein secretion

    Walter Nickel

  • Unconventional Secretion Mediates the Trans-cellular Spreading of Tau.

    Taxiarchis Katsinelos;Marcel Zeitler;Eleni Dimou;Andromachi Karakatsani

  • Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2

    Christoph Zehe;André Engling;Sabine Wegehingel;Tobias Schäfer

  • Unconventional Secretion of Fibroblast Growth Factor 2 Is Mediated by Direct Translocation across the Plasma Membrane of Mammalian Cells

    Tobias Schäfer;Hanswalter Zentgraf;Christoph Zehe;Britta Brügger

  • The cancer antigen CA125 represents a novel counter receptor for galectin-1

    Claudia Seelenmeyer;Sabine Wegehingel;Johannes Lechner;Walter Nickel

  • A conserved, lipid-mediated sorting mechanism of yeast Ist2 and mammalian STIM proteins to the peripheral ER.

    Ebru Ercan;Frank Momburg;Ulrike Engel;Koen Temmerman

  • Uptake by COPI-coated vesicles of both anterograde and retrograde cargo is inhibited by GTPgammaS in vitro

    W. Nickel;J. Malsam;K. Gorgas;M. Ravazzola

  • Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells

    André Engling;Rafael Backhaus;Carolin Stegmayer;Christoph Zehe

Frequent Co-Authors

Felix T. Wieland
Felix T. Wieland Heidelberg University
Britta Brügger
Britta Brügger Heidelberg University
Ana J. García-Sáez
Ana J. García-Sáez University of Cologne
Rainer Pepperkok
Rainer Pepperkok European Molecular Biology Laboratory
Jürgen Bernhagen
Jürgen Bernhagen Ludwig-Maximilians-Universität München
Catherine Rabouille
Catherine Rabouille Hubrecht Institute for Developmental Biology and Stem Cell Research
Matthias P. Mayer
Matthias P. Mayer Heidelberg University
Deborah F. Smith
Deborah F. Smith University of York
Oliver T. Fackler
Oliver T. Fackler University Hospital Heidelberg
Martin Hof
Martin Hof Czech Academy of Sciences

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