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Jacques Magdalou

Jacques Magdalou

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
10586
World Ranking
16622
National Ranking
698

Overview

Jacques Magdalou is affiliated with the University of Lorraine in France. Their research primarily centers on biomedical topics within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed to a range of studies focusing on developmental and metabolic processes, particularly those related to prenatal exposure effects and musculoskeletal health.

Magdalou's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of their research encompass:

  • Pediatrics, Perinatology and Child Health
  • Nutrition and Dietetics
  • Rheumatology
  • Molecular Biology
  • Endocrinology, Diabetes and Metabolism

The scientist has explored a variety of topics with multiple publications addressing:

  • Birth, Development, and Health
  • Fatty Acid Research and Health
  • Osteoarthritis Treatment and Mechanisms
  • Growth Hormone and Insulin-like Growth Factors
  • Adipose Tissue and Metabolism
  • Pregnancy-related medical research
  • Bone Metabolism and Diseases

Jacques Magdalou has contributed to various journals and scientific venues, frequently publishing in:

  • Bone
  • British Journal of Pharmacology
  • Food and Chemical Toxicology
  • Toxicology
  • Stem Cell Research & Therapy

Representative recent papers include:

  • The low-expression programming of 11β-HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats, 2020, British Journal of Pharmacology
  • GR/HDAC2/TGFβR1 pathway contributes to prenatal caffeine induced-osteoarthritis susceptibility in male adult offspring rats, 2020, Food and Chemical Toxicology
  • Subchondral bone dysplasia partly participates in prenatal dexamethasone induced-osteoarthritis susceptibility in female offspring rats, 2020, Bone
  • H3K9ac of TGFβRI in human umbilical cord: a potential biomarker for evaluating cartilage differentiation and susceptibility to osteoarthritis via a two-step strategy, 2021, Stem Cell Research & Therapy
  • Articular damages in multi-generational female offspring due to prenatal caffeine exposure correlates with H3K9 deacetylation of TGFβ signaling pathway, 2020, Toxicology

Frequent co-authors in their research efforts include:

  • Hui Wang
  • Liaobin Chen
  • Hao Xiao
  • Jean-François Stoltz

Jacques Magdalou also contributed to academic literature through book publication. One such work published by Elsevier BV is Stem Cells and Regenerative Medicine, released in 2021.

Best Publications

  • The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

    Peter I. Mackenzie;Ida S. Owens;Brian Burchell;K. W. Bock

  • Interleukin‐1β down‐regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: Influence of glucosamine on interleukin‐1β–mediated effects in rat chondrocytes

    Jean-Noel Gouze;Karim Bordji;Sandrine Gulberti;Bernard Terlain

  • Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-κB pathway

    J.N. Gouze;A. Bianchi;P. Bécuwe;M. Dauça

  • Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century

    J.-F. Stoltz;N. de Isla;Y. P. Li;D. Bensoussan

  • Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes

    Karim Bordji;Joël-Paul Grillasca;Jean-Noël Gouze;Jacques Magdalou

  • Caffeine-Induced Activated Glucocorticoid Metabolism in the Hippocampus Causes Hypothalamic-Pituitary-Adrenal Axis Inhibition in Fetal Rats

    Dan Xu;Benjian Zhang;Gai Liang;Jie Ping

  • Metabolism of Parabens (4-Hydroxybenzoic Acid Esters) by Hepatic Esterases and UDP-Glucuronosyltransferases in Man

    Suzanne Abbas;Hélène Greige-Gerges;Nancy Karam;Marie-Hélène Piet

  • An internal signal sequence mediates the targeting and retention of the human UDP-glucuronosyltransferase 1A6 to the endoplasmic reticulum.

    Mohamed Ouzzine;Jacques Magdalou;Brian Burchell;Sylvie Fournel-Gigleux

  • Regioselective and stereospecific glucuronidation of trans- and cis-resveratrol in human.

    Virginie Aumont;Stéphanie Krisa;Eric Battaglia;Patrick Netter

  • A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.

    M Pritchard;S Fournel-Gigleux;G Siest;P Mackenzie

  • Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation

    Yang Tan;Jin Liu;Yu Deng;Hong Cao

  • Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats

    Lang Shen;Zhongfen Liu;Jun Gong;Li Zhang

  • Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair.

    N. Venkatesan;L. Barre;A. Benani;Patrick Netter

  • Phosphorylation and Sulfation of Oligosaccharide Substrates Critically Influence the Activity of Human β1,4-Galactosyltransferase 7 (GalT-I) and β1,3-Glucuronosyltransferase I (GlcAT-I) Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans

    Sandrine Gulberti;Virginie Lattard;Magali Fondeur;Jean-Claude Jacquinet

  • Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4.

    T Pillot;M Ouzzine;S Fournel-Gigleux;C Lafaurie

  • A hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in offspring rats of IUGR induced by prenatal caffeine ingestion.

    D. Xu;Y. Wu;F. Liu;Y.S. Liu

  • In vitro N-glucuronidation of a novel antiepileptic drug, lamotrigine, by human liver microsomes.

    J Magdalou;R Herber;R Bidault;G Siest

  • Nicotine-induced over-exposure to maternal glucocorticoid and activated glucocorticoid metabolism causes hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic alterations in fetal rats

    D. Xu;G. Liang;Y.E. Yan;W.W. He

  • Presence of a Retinoid Responsive Element in the Promoter Region of the Human Cytochrome P4501A1 Gene

    F. Vecchini;M.C. Lenoirviale;C. Cathelineau;J. Magdalou

  • The glucuronosyltransferases: what progress can pharmacologists expect from molecular biology and cellular enzymology?

    Gérard Siest;Bénédicte Antoine;Sylvie Fournel;Jacques Magdalou

Frequent Co-Authors

Patrick Netter
Patrick Netter University of Lorraine
Hui Wang
Hui Wang University of Ulster
Brian Burchell
Brian Burchell University of Dundee
Jun Qin
Jun Qin Baylor College of Medicine
Bruce D. Hammock
Bruce D. Hammock University of California, Davis
Jean A. Boutin
Jean A. Boutin Institut de Recherches Internationales Servier
Philippe Gillet
Philippe Gillet École Polytechnique Fédérale de Lausanne
Michael W.H. Coughtrie
Michael W.H. Coughtrie University of British Columbia
Franz Oesch
Franz Oesch Johannes Gutenberg University of Mainz
Qibing Mei
Qibing Mei Air Force Medical University

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