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Risto Kostiainen

Risto Kostiainen

D-Index & Metrics

Chemistry

D-Index
71
Citations
14975
World Ranking
5684
National Ranking
25

Overview

Risto Kostiainen is affiliated with the University of Helsinki in Finland and has contributed extensively to research in the fields of Biochemistry, Genetics and Molecular Biology, as well as Chemistry. Their work bridges several subfields including Spectroscopy, Molecular Biology, Clinical Biochemistry, Neurology, and Epidemiology.

The primary focus of their research lies in Mass Spectrometry Techniques and Applications, supported by studies in Metabolomics and Mass Spectrometry, along with investigations into Metabolism and Genetic Disorders. Additional topics of their research include Neuroinflammation and Neurodegeneration Mechanisms, Autophagy in Disease and Therapy, Extracellular Vesicles in Disease, and Analytical Chemistry and Chromatography.

Risto Kostiainen has published in multiple scientific journals with varied focus areas. Frequent publication venues include:

  • Analytical Chemistry
  • Experimental Neurology
  • Journal of the American Society for Mass Spectrometry
  • Journal of Chromatography A
  • Journal of Proteome Research

Their recent research output includes the following papers:

  • Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF, 2020, Experimental Neurology
  • Sub-100 μm Spatial Resolution Ambient Mass Spectrometry Imaging of Rodent Brain with Laser Ablation Atmospheric Pressure Photoionization (LAAPPI) and Laser Ablation Electrospray Ionization (LAESI), 2020, Analytical Chemistry
  • Mass Spectrometry Imaging of Arabidopsis thaliana Leaves at the Single-Cell Level by Infrared Laser Ablation Atmospheric Pressure Photoionization (LAAPPI), 2021, Journal of the American Society for Mass Spectrometry
  • Multiplexed analysis of amino acids in mice brain microdialysis samples using isobaric labeling and liquid chromatography-high resolution tandem mass spectrometry, 2021, Journal of Chromatography A
  • Soft X-ray Atmospheric Pressure Photoionization in Liquid Chromatography-Mass Spectrometry, 2021, Analytical Chemistry

Collaborative work is a notable aspect of their research, with frequent coauthors including Jaakko Teppo, Juho Heininen, Tapio Kotiaho, Juha-Pekka Hieta, and Heikki Räikkönen. These partnerships have contributed to a range of studies in related disciplines.

Best Publications

  • A high-resolution mass spectrometer to measure atmospheric ion composition

    H. Junninen;M. Ehn;T. Petäjä;L. Luosujärvi

  • Effect of eluent on the ionization process in liquid chromatography-mass spectrometry.

    Risto Kostiainen;Tiina J. Kauppila

  • Liquid chromatography/atmospheric pressure ionization-mass spectrometry in drug metabolism studies.

    R. Kostiainen;T. Kotiaho;T. Kuuranne;S. Auriola

  • Quantitative determination of phospholipid compositions by ESI-MS: effects of acyl chain length, unsaturation, and lipid concentration on instrument response.

    Mirkka Koivusalo;Perttu Haimi;Liisa Heikinheimo;Risto Kostiainen

  • Atmospheric pressure photoionization mass spectrometry. Ionization mechanism and the effect of solvent on the ionization of naphthalenes.

    Tiina J. Kauppila;Tiia Kuuranne;Eduardo C. Meurer;Marcos N. Eberlin

  • Volatile organic compounds in the indoor air of normal and sick houses

    Risto Kostiainen

  • Desorption atmospheric pressure photoionization.

    Markus Haapala;Jaroslav Pol;Ville Saarela;Ville Arvola

  • Liquid chromatography/mass spectrometry in anabolic steroid analysis-optimization and comparison of three ionization techniques: electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization

    A Leinonen;T Kuuranne;R Kostiainen

  • Effect of eluent on the ionization efficiency of flavonoids by ion spray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization mass spectrometry.

    Jussi-Pekka Rauha;Heikki Vuorela;Risto Kostiainen

  • Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than the other UGTs and was purified as an active dimeric enzyme

    Mika Kurkela;J. Arturo Garcı́a-Horsman;Leena Luukkanen;Saila Mörsky

  • Desorption electrospray ionization mass spectrometry for the analysis of pharmaceuticals and metabolites.

    Tiina J. Kauppila;Tiina J. Kauppila;Justin M. Wiseman;Raimo A. Ketola;Tapio Kotiaho

  • Negative ion-atmospheric pressure photoionization-mass spectrometry.

    Tiina J. Kauppila;Tapio Kotiaho;Risto Kostiainen;Andries P. Bruins

  • Introduction to micro-analytical systems: bioanalytical and pharmaceutical applications

    Katri Huikko;Risto Kostiainen;Tapio Kotiaho

  • Anisole, a new dopant for atmospheric pressure photoionization mass spectrometry of low proton affinity, low ionization energy compounds.

    Tiina J. Kauppila;Risto Kostiainen;Andries P. Bruins

  • Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles.

    Hanna Valo;Leena Peltonen;Satu Vehviläinen;Milja Karjalainen

  • Electrospray mass and tandem mass spectrometry identification of ozone oxidation products of amino acids and small peptides.

    Tapio Kotiaho;Marcos N. Eberlin;Pirjo Vainiotalo;Risto Kostiainen

  • Rapid analysis of metabolites and drugs of abuse from urine samples by desorption electrospray ionization-mass spectrometry

    Tiina J. Kauppila;Tiina J. Kauppila;Nari Talaty;Tiia Kuuranne;Tapio Kotiaho

  • Comparison of Electrospray, Atmospheric Pressure Chemical Ionization, and Atmospheric Pressure Photoionization in the Identification of Apomorphine, Dobutamine, and Entacapone Phase II Metabolites in Biological Samples

    Helena Keski-Hynnilä;Mika Kurkela;Eivor Elovaara;Laurence Antonio

  • Electrospray and atmospheric pressure chemical ionization tandem mass spectrometric behavior of eight anabolic steroid glucuronides.

    Tiia Kuuranne;Mikko Vahermo;Antti Leinonen;Risto Kostiainen

  • Screening of free 17-alkyl-substituted anabolic steroids in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry.

    Antti Leinonen;Tiia Kuuranne;Tapio Kotiaho;Risto Kostiainen

  • Microchip technology in mass spectrometry.

    Tiina Sikanen;Sami Franssila;Tiina J. Kauppila;Risto Kostiainen

Frequent Co-Authors

Tapio Kotiaho
Tapio Kotiaho University of Helsinki
Sami Franssila
Sami Franssila Aalto University
Raimo A. Ketola
Raimo A. Ketola Finnish Institute for Health and Welfare (THL)
Moshe Finel
Moshe Finel University of Helsinki
Mikko Ritala
Mikko Ritala University of Helsinki
Jouni Hirvonen
Jouni Hirvonen University of Helsinki
Mario Thevis
Mario Thevis German Sport University Cologne
Seppo Auriola
Seppo Auriola University of Eastern Finland
Wilhelm Schänzer
Wilhelm Schänzer German Sport University Cologne
Tuulia Hyötyläinen
Tuulia Hyötyläinen Örebro University

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